Development and Internal Validation of a Multivariable Prediction Model for the Sexual Function of Cervical Cancer Survivors

Article Type:
Research/Original Article (دارای رتبه معتبر)
Background & Objective

Sexual dysfunction is the symptom with the greatest negative impact on the quality of life of cervical cancer survivors. However, the evaluation of sexual function is challenging, and there is ongoing debate concerning its determinants. We aimed to identify predictive variables for sexual function after cervical cancer treatment.

Materials & Methods

One hundred and four cervical cancer survivors participated in a prospective cohort study that we carried out employing FACT–Cx v.4.0 and FSFI questionnaires.


We developed a beta generalized linear model with a predictive accuracy of 78% (C–index=0.78) and based on vaginal shortening (Cx4) (P=0.077), age (P=0.0002), and ovarian preservation (P=0.01) as risk factors, and functional well–being (P<0.0001) and follow–up duration (P=0.015) as protective factors.


To the best of our knowledge, we may have created the first reliable and internally validated prediction model for cervical cancer survivors based on predictors like vaginal shortening, age, ovarian preservation, functional well–being, and follow–up duration that significantly affect female sexual function as targets for potential intervention.

Journal of Obstetrics, Gynecology and Cancer Research, Volume:9 Issue: 2, Mar-Apr 2024
201 to 211  
دانلود و مطالعه متن این مقاله با یکی از روشهای زیر امکان پذیر است:
اشتراک شخصی
با عضویت و پرداخت آنلاین حق اشتراک یک‌ساله به مبلغ 1,390,000ريال می‌توانید 70 عنوان مطلب دانلود کنید!
اشتراک سازمانی
به کتابخانه دانشگاه یا محل کار خود پیشنهاد کنید تا اشتراک سازمانی این پایگاه را برای دسترسی نامحدود همه کاربران به متن مطالب تهیه نمایند!
  • حق عضویت دریافتی صرف حمایت از نشریات عضو و نگهداری، تکمیل و توسعه مگیران می‌شود.
  • پرداخت حق اشتراک و دانلود مقالات اجازه بازنشر آن در سایر رسانه‌های چاپی و دیجیتال را به کاربر نمی‌دهد.
In order to view content subscription is required

Personal subscription
Subscribe for 70 € euros via PayPal and download 70 articles during a year.
Organization subscription
Please contact us to subscribe your university or library for unlimited access!