Efficacy of Propolis-Based Mouthwash on Generalized Chronic Gingivitis: A Randomized Controlled Clinical Trial

This study aimed to investigate the effect of propolis-based mouthwash on the gingival parameters of generalized chronic gingivitiscasesin a randomized controlled clinical trial.

A total number of 69patients with generalized chronic gingivitis were randomly assignedinto three groups(N=23): propolis, chlorhexidine, or placebo mouthwash. The gingival and bleeding indices were evaluated before and after two weeks of mouthwash use.Data analyses were performed usingKruskal-Wallis test, one-way analysis of variance, and paired t-test at p<0.05.

The average gingival index in the chlorhexidine group was significantlyhigher than in the propolis group (p=0.005), but there was no significant difference between the placebo and propolis mouthwash groups (p=0.080). Moreover, the average plaqueindex was significantly higher in the chlorhexidine group than the propolis group (p<0.001). However, no significant difference was observed between the placebo and propolis mouthwash groups (p=0.742). However, the average bleeding index in the chlorhexidine group was significantly lower than the propolis group (p=0.012), with no significant difference between the placebo and propolis mouthwash groups (p=0.134).

The present results showed that scaling and propolis mouthwash consumption significantly improved the bleeding on probing and the gingival indicescompared tothe placebo group. Therefore, this mouthwash can beuseful for treating chronic generalized gingivitis.