The Comparative Effects of Platelet-Rich Plasma and Polycaprolactone-Hydroxyapatite Zeolite Nanocomposites on Wound Healing After Tooth Extraction

Post tooth extraction type of wound healing is a convoluted process that helps wounds reform. This study aims to evaluate the impact of polycaprolactone-hydroxyapatite zeolite nanocomposites on the healing processes of mucosa overlying post-extraction alveolus.

Fifteen healthy cats with premolar lower tooth involvement were selected for tooth extraction. The biopsy sampling from the mucosa of the alveolus was performed on the 10th postoperative day. The cats were grouped as control, plateletrich plasma (PRP), and nano polycaprolactone-hydroxyapatite zeolite.

The histopathologic analysis showed that contrary to controls and PRP, the nano group had a lower presence of inflammatory cells, a complete irregular thick epithelium, more granulation tissue, and more fibrosis. So, nano polycaprolactonehydroxyapatite zeolite accelerated the healing process after tooth extraction.

Nanocomposite containing nano zeolite can improve wound healing after tooth extraction.