Clinical and laboratory findings of hospitalized older adults with covid-19 in Isfahan in 2021

The covid-19 pandemic has caused many injuries and increased mortality in older adults. Timely diagnosis and treatment is related to the reduction of mortality. The present study was designed and implemented by examining the clinical and laboratory findings before hospitalization of older adults with coronavirus disease, in order to find the relationship between these findings and the mortality risk of these patients.

During a retrospective descriptive-analytical study, the file information of 534 older adults patients admitted to Dr. Gharazi Hospital in Isfahan in the spring of 1400 with the diagnosis of covid-19 was randomly selected. The diagnosis of the disease was based on the findings of lung CT scan and PCR. Statistical analysis was performed by SPSS version 24 software using chi-square statistical tests, t-test and multinomial logistic regression.

Average age was 72.49 ± 8.76 years in the study. At the end of hospitalization, 124 patients (23.2%) died. The average age of deceased patients was significantly higher than other patients. In the analysis of the data, it was found that history of diabetes (Exp (B): 1.84, 95%CI: 1.032-3.284, P=0.039), decreased oxygen saturation (O2sat<90%) (Exp (B): 5.80, 95%CI: 5=15.37-2.19, P<0.001), increased absolute number of neutrophils (>8000/mcL) (Exp (B): 2.41, 95%CI: 1.36-4.29, P=0.003), increased C-Reactive Protein (CRP) ) (>150mg/dl) (Exp (B): 1.94, 95%CI: 1.10-3.41, P=0.021) were significantly predictive of death in older adults with coronavirus infection.

The present study showed that increasing age, diabetes, decrease in oxygen saturation, increase in neutrophils and increase in CRP are independent prognostic factors predicting death in older adults with Coronavirus infection. Which can reduce the mortality of older adult’s people with corona by identifying it in time.