Serological study of Toxoplasmosis In Women with previous history of abortion or still birth Referred to Sari, s Medical centers during the years 1376-1377

Background and

Toxoplasmosis is a common disease of human & animals (Zoonosis) which has a world wide distribution. Ïnfection with Toxoplasma gondii in pregnant women produces a different clinical features such as abortion and still birth. This study was performed in order to determine the titer of anti Toxoplasma antibody in women with the history of abortion or still birth referring to Sari, s Medical Çenters during the years 1376-1377.

Ïn the descriptive study, serum samples of 200 pregnant women in age groups of 26.2 ± 4.8 who had a history of abortion or still birth referring to Sari, s medical centers during Farvardin 76 to Ësphand 77 were examined. For serological studies, antibody titration for ÏgM and ÏgG were determined by indirect immunofluorescence technique.

Ïn this study, 75 patients (37.5%) of aborted women were seropositive for Toxoplasma ≥ 1/100. 45 of them (60%) had a titer equal to or less than 1/400 and 30 women (40%) had a titer more than 1/400. Ïn all, only 3 women (1.5%) had ÏgM antibody. There was no statistically significant difference between the rate of anti toxoplasma gondii antibody in women of urban and rural areas. Çonclusion: Perhaps toxoplasmosis is one the causes of abortion in the area, but is not the main cause, because many pregnant women are infected with toxoplasma gondii before hand.