Coenzyme Q10 may be effective in the treatment of non alcoholic fatty liver disease (NAFLD)
Abstract:
Nonalcoholic fatty liver disease (NAFLD) represents a spectrum of disorders characterized by predominantly macrovesicular hepatic steatosis that occur in individuals even in the absence of consumption of alcohol in amounts considered harmful to the liver. At present, there is no standard recommended treatment for NAFLD. Treatment currently focuses on gradual weight loss through diet and regular exercise. Insulin sensitizers such as thiazolidinediones and metformin show promise, and several studies have explored the role of lipid lowering agents and antioxidants. Coenzyme Q10 (CoQ) is a powerful antioxidant and has an important role in respiratory metabolism, as a mobile electron and proton carrier in the mitochondrial electron transport chain. However, to date, there is no published clinical trial on CoQ in NAFLD. We postulate the hypothesis that CoQ might be effective in the treatment of NAFLD.
Language:
Persian
Published:
Journal of Medical Hypotheses and Ideas, Volume:2 Issue:2, 2008
Page:
7
magiran.com/p524115  
روش‌های دسترسی به متن این مطلب
اشتراک شخصی
در سایت عضو شوید و هزینه اشتراک یک‌ساله سایت به مبلغ 300,000ريال را پرداخت کنید. همزمان با برقراری دوره اشتراک بسته دانلود 100 مطلب نیز برای شما فعال خواهد شد!
اشتراک سازمانی
به کتابخانه دانشگاه یا محل کار خود پیشنهاد کنید تا اشتراک سازمانی این پایگاه را برای دسترسی همه کاربران به متن مطالب خریداری نمایند!