The survey of abnormal glucose tolerance and insulin ‎resistace and incidence of diabetes type 2 in poly cystic ovary ‎syndrome patients in Shiraz

Polycystic ovarian syndrome is one of the most commen hyper androgenic ‎disorders affecting women, its prevalence being estimated at 5% – 10%. Our goal was to survey ‎abnormal glucose tolerance, insulin resistance and incidence of diabetes type 2 in patients with ‎polycystic ovary syndrome. This investigation is a descriptive – analytic study which is done to ‎survey abnormal glucose tolerance, insulin resistance and incidene of diabetes type 2 in polycystic ‎ovary syndrome (PCOS). This study included 150 patients with the diagnosis of PCOS. These ‎patients were chosen by target based sampling. Among the subjects, laboratory tests were ‎performed for 125 patients. Questionnaire, fasting blood suger test, fasting insulin and glucose ‎tolerance test by 75gr glucose, were used as data gathering tools. The results of the blood suger test ‎were interpreted using the WHO 1999 criteria. The results of oral and glucose tolerance test showed 14. 4 percent of the patients had ‎impaired fasting glucose and 4 percent of the patients had diabetes type 2 (FBS>126mg/dl). Insulin ‎resistance was seen in 9. 8 percent of the patients. 7. 2 percent of the patients had impaired blood ‎suger after two hours (140-199 mg/dl) and 0. 8 persent of patients had diabetes type 2 (200>mg/dl). level of fasting blood suger and insulin and ratio of fasting blood suger to fasting ‎insulin were good markers for diagnosis of insulin resistance. American diabetic association recommended for the care of young women with PCOS, screening ‎for impaired glucose tolerance and diabetes type2. ‎