Five Year's Retrospective Study of Oral and Maxillofacial Malignancies in Patients Referred to Oral Medicine Department of Mashhad Dental School-Iran

In spite of recent progresses in cancer treatment; the oral cancer is still one of ten most common causes of death because of late diagnosis (the reasons for that is similarity of clinical presentation with some of the benign lesions symptomless in early stages and variety of clinical manifestation…). Considering the role of cultural and geographical factors in oral cancer prevalence epidemiological studies are of great importance. The aim of this research is to determine five years prevalence of orofacial malignancies of the patients referred to Oral Medicine Department Mashhad Dental School Iran. A deh1ive and retrospective study was done using 44 medical files of patients whose oral and maxillofacial malignancy was histopothologically confirmed. (From November 2000 to November 2005) demographic clinical and histopathological data were extracted. We’ve used SPSS software to analyze data and drawing table and charts. Squamous cell carcinoma (SCC) was the most common malignancy (73%) followed by verrucous carcinoma (10%) and salivary gland carcinoma (7%). Male to female ratio was 0.9/1 and age average was 53.5217.66. The most common clinical feature of SCC was ulcer and exophytic lesion (%34) and other malignancy mostly appeared as exophytic lesion (%67). The most prevalent chief complains of oral SCC patients was ulcer (41%) and tongue was the most common site (30%). Although most of epidemiological patterns of oral SCC were similar to other researches but females had a higher incidence rate than males and surprisingly tobacco use was markedly low in comparison to other studies.