The role of myocardial perfusion imaging in the screening of silent ischemia in diabetic patients

More than 70%of diabetes patients die from cardiovascular causes. Furthermore, consequences of coronary artery disease (CAD) are more severe, because myocardial ischemia is often silent in these patients. Selecting only patients who met American Heart Association guideline have failed to identify 41% of patients with silent ischemia. Pointing to the need to modify these guidelines, further better procurers to identify those who may benefit from screening are required. The sample size of this study was the articles indexed in pubmed, Elsevier, Tripdatabase, Embase, Black Cochrane, New spring link,Ovid and contained the terms “diabetes, cardiac perfusion scan, silent ischemia”. 698 articles were found that 68 articles were investigated for this issue. The results are discussed under the subtitle such as silent ischemia mechanism, myocardial perfusion imaging and clinical indeces; and also the efficacy of myocardial perfusion imaging in comparison with other modalities. In this summary, we tried to review the current literature about who will benefit from myocardial perfusion scan screening as well as the best individualized test and reach a comprehensive guideline for practical significance of this subject in routines practice