Acute Fulminant Facial Cellulitis as the Presenting Sign of Acute Myelogenous Leukemia

To report a case of acute myelogenous leukemia (AML) presenting with periorbital cellulitis and progressing to facial and neck cellulitis. Case Report: A 17 year old male patient presented with periorbital cellulitis which progressed to the right hemifacial and neck area. He did not respond to regular antibiotic therapy. Peripheral blood smear showed leukocytosis with predominance of immature cells, thrombocytopenia and anemia. Bone marrow biopsy confirmed a diagnosis of acute myelogenous leukemia. Acute leukemia must be considered in the differential diagnosis of periorbital cellulitis.