Study on Prevalence of TTV among Cirrhotic patients due to Hepatitis B & C in Ahwaz University Hospitals during the Years 2004-2005

Message:
Abstract:
Background And Aims
Recently, a novel DNA virus was isolated from the serum of a patient with post-transfusion non A-G hepatitis and named TT virus. The aim of this study was to determine the prevalence TT virus among cirrhotic patients due to hepatitis B & C in infection Ahwaz.
Methods
The prevalence of TTV infection was studied in 41 patients with liver cirrhosis. TTV DNA was detected by semi-nested PCR. The plasma samples were tested for marker hepatitis B & C by ELISA test.
Results
TT virus was detected in 17(41.46%) of the 41 patients with cirrhotic liver disease. There were no significant difference between the subject TTV DNA in relation to sex and age. TTV positivity in cirrhotic patient infected with hepatitis B (52.9%) was higher than in similar patients infected with hepatitis C (47.1%).
Conclusion
TTV infection was highly prevalence in patient with cirrhotic hepatitis, especially in those with hepatitis B virus infection.
Language:
English
Published:
Iranian Journal of Virology, Volume:3 Issue: 1, 2009
Page:
29
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