The Relationship between Air Pollution and Serum Level of Thrombomodu-lin and Tissue Factor in a Representative Sample of Adolescents Aged 10-18 Years in Isfahan, Iran
Message:
Abstract:
Background

Studying the effects of environmental factors on the early stages of development and progression of atherosclerosis process can serve as a guide for future studies and offer strategies for primary prevention of chronic diseases. This study aimed to assess the relationship of air pollution and plasma surrogate endothelial markers in the pediatric age group.

Methods

This cross-sectional study conducted in 2010 involving 118 children and adolescents aged 10-18 years randomly selected from different areas of Isfahan city, the second large and air-polluted city in Iran. The association of air pollutants’ levels with serum thrombomodulin (TM) and tissue factor (TF) was determined.

Findings

A significant relationship between TF and Pollution Standard Index (PSI) was found. This relationship was remarkable with PM level, although we could find this relationship more or less with other gasses as well. In this study, no significant relationship was found between TM and PSI.

Conclusion

The relationship of air pollution level with the inflammation system and subsequently coagulation factors can be an important factor in atherosclerosis development from early life. This finding should be confirmed in future longitudinal studies and must be given due attention in preventive policies.

Language:
Persian
Published:
Journal Of Isfahan Medical School, Volume:28 Issue: 109, 2010
Page:
425
magiran.com/p779095  
دانلود و مطالعه متن این مقاله با یکی از روشهای زیر امکان پذیر است:
اشتراک شخصی
با عضویت و پرداخت آنلاین حق اشتراک یک‌ساله به مبلغ 990,000ريال می‌توانید 70 عنوان مطلب دانلود کنید!
اشتراک سازمانی
به کتابخانه دانشگاه یا محل کار خود پیشنهاد کنید تا اشتراک سازمانی این پایگاه را برای دسترسی نامحدود همه کاربران به متن مطالب تهیه نمایند!
توجه!
  • حق عضویت دریافتی صرف حمایت از نشریات عضو و نگهداری، تکمیل و توسعه مگیران می‌شود.
  • پرداخت حق اشتراک و دانلود مقالات اجازه بازنشر آن در سایر رسانه‌های چاپی و دیجیتال را به کاربر نمی‌دهد.
دسترسی سراسری کاربران دانشگاه پیام نور!
اعضای هیئت علمی و دانشجویان دانشگاه پیام نور در سراسر کشور، در صورت ثبت نام با ایمیل دانشگاهی، تا پایان فروردین ماه 1403 به مقالات سایت دسترسی خواهند داشت!
In order to view content subscription is required

Personal subscription
Subscribe magiran.com for 50 € euros via PayPal and download 70 articles during a year.
Organization subscription
Please contact us to subscribe your university or library for unlimited access!