GLYCOSYLATED HAEMOGLOBIN IN PATIENTS WITH ESSENTIAL HYPERTENSION

Message:
Abstract:
Introduction
In this study, we compared the level of glycosylated haemoglobin in patients with essential hypertension and healthy controls.
Method
70 non-diabetic patients with essential hypertension were recruited into the study along with 140 controls without any significant medical history. Persons with a history of metabolic disease, anaemia, renal disease, splenectomy, pregnancy, or on medication were excluded from the study. A blood sample was taken from each participant and immediately sent to the EEMRC laboratory, where fasting blood sugar and glycosylated haemoglobin levels were measured by the glucose oxidase and thiobarbituric acid (colorimetry) method, respectively. The unpaired t-test was used to compare means. A p-value of less than 0.05 was considered significant.
Results
Mean fasting blood glucose was 103.1±16.1mg/dl in the hypertensive group and 92±7mg/dl in controls (p<0.05). Mean glycosylated haemoglobin levels were 7.38±0.78% in the hypertensive group and 6.5±0.85% in controls (p<0.05).
Conclusion
People with essential hypertension have a higher level of glycosylated haemoglobin than healthy controls.
Language:
Persian
Published:
Iranian Journal of Diabetes and Lipid Disorders, Volume:1 Issue: 2, 2002
Page:
115
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