Effects of anti-nociceptive and anti-inflammatory component of limonene in herbal drugs

Nature has served a rich repository of medicinal plants for thousands of years and impressive numbers of modern drugs have been isolated from natural sources، notably of plant origin. In this research anti-nociceptive and anti-inflammatory effects of Limonene have been been investigated. Anti-nociceptive activity was investigated using formalin test method. Anti-inflammation activity was investigated using xylene test method and for limonene production decantation method was used. For investigation of anti-nociceptive activity، limonene was injected to mice in three different doses as 20، 30 and 50 mg/kg. The results showed 50 mg/Kg injection had the maximum anti-nociceptive and anti-inflammatory effect.