Simultaneous Üse of Ültrasonography and TÇ99mSS Scan in the Diagnosis of Hyperparathyroidism Preoperatively

Background and Nowadays، studies on localizing hyperparathyroidism suggest a replacement of bilateral neck surgery of parathyroid with unilateral exploration. The purpose of this study was to survey the simultaneous use of Ültrasonography (ÜS) and 99TÇMSS to localize the hyper function of parathyroid gland preoperatively. Â descriptive، retrospective case-series study was carried out on 25 patients with hyperparathyroidism whose parathyroid adenomas localized by ÜS or 99TÇMSS and underwent surgery between 1999 and 2009. This study involves a retrospective collection of demographic، biochemical and imaging data as well as pathologic and surgical information. The results of imaging studies were compared with surgical and histological findings. The sensitivity of ÜS and SS were higher for adenomas (53% and 83%) than hyperplastic glands (50% and 66%). The sensitivity and PPV in simultaneous use of ÜS and SS to localize single adenoma were 84% and 100%، respectively. Çonclusion: Since even one parathyroid lesion was not solely identified using ÜS، there was not a statistically significant difference on the sensitivity of scintigraphy between 99TÇMSS and simultaneous use of ÜS and 99TÇMSS (P<0. 05). Therefore، 99TÇMSS is recommended if parathyroid localization prior to unilateral surgery is required.