Correlation of inflammatory and nutrient intake in Isfahan hemodialysis patients

Protein energy malnutrition and inflammation in hemodialysis (HD) patients often leads to the malnutrition inflammation complex syndrome or atherosclerosis malnutrition and inflammation related to the atherosclerotic cardiovascular disease. This syndrome occurs in patients undergoing dialysis for a long time and is accounted as an important factor of mortality among these patients.Considering that different studies showed different results about inflammation and malnutrition, we decided to investigate the relation of inflammatory and nutritional indices in HD patients. This research was done by cross-sectional method on 35 HD patients of Alzahra hospital being dialyzed for at least 6 months. Data were collected by a questionnaire containing personal and medical characteristics and clinical tests and food frequency questionnaire (FFQ). The persons being studied (20 men, 15 women) aged 51 on the average..Anthropometric characteristics including height and weight were measured using a seca scale and height meter and the blood samples of patients were taken and sent to the laboratory for the biochemical tests. Food frequency questionnaires including 192 questions were completed and the obtained results were analyzed by SPSS software. The relation between selenium and TG and CRP was meaningful (P=0.000) and about other investigated indices (albumin, cholesterol, calorie, protein, vitamins and minerals) no meaningful relation was observed. In this study CRP as the inflammatory index and albumin as the nutritional index were measured. 25.9% of people had albumin less than 3.5g/dl who were suffering from malnutrition or were prone to it, and 23.8% had CRP less than 1mg/dL which is indicative of the existence of inflammation in these people. There was no meaningful relation between CRP and albumin in many participants, probably because of being hemodialysed for short-term. Then, many participants in the study have not been involved in the inflammation-malnutrition cycle yet.