The effect of intra peritoneal injection of foeniculum vulgare seed alcoholic extract on Epididyms and deferens and Epidiymal Sperm Rasevr in male wistar rate
Message:
Abstract:
Always population increase is assumed one the basic problems of society and population control with chemical drugs are one of the most human concerns. Side effects of use these drugs drive human to use of vegetable drugs. Foeniculum vulgare is one of them witching this current study addressed to survey the effect of its seed alcoholic extract on Epididyms and deferens Epidiymal Sperm Rasevr (ESR). In this study is used the male rat of wistar race 2-3 month aged. (with the approximated weight of 190 ±10 gr). Animal was classified to four experimental group and one control groups. Four experimental group for 15 days was received the doses of 35,70,140, 280 μlit of fennel seed alcoholic extract. At this time was inject the physiology serum to control group intra peritoneal (IP). In 15th day rats in each group have been unconscious with a mixture of 2% zayelzin and 10% ketamine)100 mg/kg (Then their stomach were swelled. And genital organ Epididyms and deferens were exited and weighted with digital scale. After weighting Epididyms was placed in 1ml solution of physiology serum with the temperature of 37C. Tail of Epididium has been cut and After wear away monotonousness solution from it was been prepared sperms was counted. Comparison between weighting Epididium and deferens have been shown that is a significant decrease difference in 140, 280 μlit experimental group than control group. (p?0.05).But in remainder experimental group as compared with group and between of groups is not a significant difference.(p?0.05). In addition to the results are shown that measure sperm rasevr (ESR) in experimental group with 140,280 μlit as compared with control group have significant decrease difference. (p?0.05). But in remainder experimental groups as compared with control group and among of groups are not a significant difference in ESR.(p?0.05). Significant decreases in sperms rates for decrease weight of Epididium and deferens and ESR rates are indicator of effect of alcoholic extraction of fennel seed in decrease the activities of male reproduction. It is maybe depended with material of feenel for example Anothol and Comarine and …or also depended with changes of hormonoes. Cheeping and having suitable flavor are some benefits and advantages of this vegetable. It is worthy in order to determination of does that which in produce of sperm was stop entirely and considering its lateral effects require more studies.
Language:
Persian
Published:
Journal of Veterinary Microbiology, Volume:6 Issue: 2, 2011
Page:
169
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