Study of the Effect of Fumariaparviflora AlcoholicExtract on Spermatogenesis in Male Rats

Aim and Background. Spermatogenesis is a process In which spermatozoids Is produced Whose defectin each stepany defect in each step can Can result result in infertility. F. parviflora contains isoquinoline andprotopine alkaloids and has antioxidant activity. F. parviflora has been used in folk medicine for its pharma-ceutical properties. One of the most important effects of this plant is increasing sexuality.The aim of this study is to investigate the effect of the F. parviflora alcoholic extract in spermatogenesisprocess.Materials and Methods.Wistar male rats (230 ± 5) are divided into 2 groups: control and experimental. The control group received distilled water whereas the experimental group received 250 mg/kg w.b. F. parviflora alcoholic extract through oral gavage for 5 days. After 15 days rats were anesthesized and sacrificed andthe Testis were removed. The volume and weight of the testis were measured and the tissues were fixed. Thepreparation of tissue sectioning was accomplished by H&E staining. Germinal cell lines cells were countedwith light microscope. Statistical analysis was performed with One Way Anova using SPSS for Windows.P ≤0.05 was considered statistically significant.Results. The analysis of the results indicated there were no significant difference in weight and volume oftesticles but significant increase in the number of spermatogonia, spermatocytes, spermatozoid and Leydigcells were observed in experimental group compared to the control group (P<0.001).Conclusions.The results indicated positive effect of F. parviflora alcoholic extract on male reproductivesystem Since the number of number of sexual cells increased significantly.