The roles of metabotropic glutamate receptors III (mGluRIII) in central regulation of food intake in broiler cockerels

In This study, the role of the metabotropic glutamate receptors (group III) on the regulation of food intake in 24h food-deprived broiler cockerels was investigated. In the 36 Broiler Cockerels with an implanted intraventricular cannula in the right ventricle of brain, intracerebroventricle injections of L-AP4 (a glutamate III receptor agonist) and UBP1112 (a glutamate III receptor antagonist) were performed. Food intake was measured by computer at 15, 30, 45, 60, 90, 120, 180, and 240 minute after injection. Both L-AP4 and UBP1112 produced nonsignificant effect on food intake when compared with control group. In conclution, the metabotropic glutamate receptors (type III) may not have any role in regulation of food intake in broiler cockerels.