The relationship between hemoglobin and hematocrit in the first trimester of pregnancy and preeclampsia
Message:
Abstract:
Background

Preeclampsia is one of major reasons of mortality in mother and child and its early diagnosis is one of the most important parts of health care during pregnancy. The current study was done to find the relationship between hemoglobin and hematocrit in the first trimester of pregnancy and the incidence of preeclampsia in women referring to Milad Hospital in Tehran in 2009-2010.

Materials And Methods

This prospective cohort study was conducted on 700 pregnant women in the first trimester of pregnancy, selected by convenience sampling. Prenatal tests were run in Milad Hospital and the results were recorded. Then samples were monitored for preeclampsia until delivery. Data were analyzed by SPSS version 18 (P < 0.05).

Results

The highest percentage of research groups suffering from preeclampsia was in hemoglobin ≥12/5% g/dl and hematocrit of ≥38% group. There was a significant relationship between hemoglobin and hematocrit levels during the first trimester of pregnancy and preeclampsia (P<0.001, P=0.002). Hemoglobin of ≥ 12.45 g/dl presented a sensitivity of 85%, the specificity of 43.04%, positive predictive value of 9.63%, and negative predictive value of 97.57%. Hematocrit of ≥ 38% presented the sensitivity of 77.5%, the specificity of 50.71, the positive predictive value of 10.1%, and the negative predictive value of 96.93%.

Conclusion

The presence of high hemoglobin and hematocrit in the first trimester of pregnancy can be a predictive factor for diagnosing preeclampsia

Language:
Persian
Published:
Journal of Arak University of Medical Sciences, Volume:14 Issue: 4, 2011
Pages:
1 to 9
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