Study Of C-Reactive Protein Effect on Outcome After Coronary Artery Bypass Surgery
Message:
Abstract:
Background
Nowadays atherosclerosis phenomenon is considered as an inflammatory phenomenon.Not only CRP is a response to the acute phase but also it is sign of atherosclerosis.
Methods
In this analytic study 454 volunteer patients for coronary artery bypass graft(CABG)operation have been observed. Before being admitted to the hospital they have gone through CRP test based on mg/dl. Then All of the patients have been under CABG operation by on pump method. The surgeon, method of operation; anesthesia and treatment in ICU were the same for all of the patients. After the operation, the patients files were used to get some information regarding death, the use of balloon pump, the use of inotrop at the end of operation, ICU stay, pump time, aortic clump time and other parameters. The statistics considering any relationship between these factors and pre operation CRP level and death were analyzed.The patients have no sign of pre operation infection, inflammation and documented malignancy.
Results
For analysis correlation between pre operation CRP level and study parameters pierson and zero test was done. From the statistical point of view the correlation between addition of death,New York Heart Association (NYHA) class, pre operation MI and diabet,addition of post operation neurologic complication,pre operation EF, the use of balloon pump,addition of pump time, aortic clump time to addition of CRP level have been considered. No significant relationship was seen. But in old patients, women and somebody that had length ICU stay or uses inotrop at the end of operation CRP was high.
Conclusion
The level of pre operation CRP can be a good statical predictor for ICU stay, urgency, using Inotrop at the end of operation. But no significant correlation was observed betweendeath, pre operation EF, MI and diabet to pre operation CRP.
Language:
Persian
Published:
Journal of Medical Council of Iran, Volume:29 Issue: 2, 2011
Page:
136
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