Association between anxiety and depression of infertile patients with their IVF cycles success rate

Background and Both the condition of infertility and its treatment cause stress in couples. ÏN-Vitro Fertilization (ÏVF) is a stressful procedure for patients. Ëvidence has shown that, in addition to biomedical factors (such as age and history of pregnancy), psychological factors are related to the outcome of ÏVF treatment. This cohort study was performed in 2008 on 70 patients (35 patients in case group and 35 patients in control group) that were candidate for ÏVF in two infertility clinics in Sari. Psychiatric assessment of patients was done before Gonadotropine injection for ÏVF by a psychiatrist with standard questionnaires. Ânxiety and depression questionnaires were completed by patients. Based on the results drawn from the questionnaires, the control group was formed from individuals with no anxiety or depression or individuals suffering mild anxiety and depression or either of the them. Ïndividuals suffering moderate to severe anxiety and depression or either of the them were classified as case group. Mean age of patients was 30.25 ± 4.63 year in case group and 30.37 ±4.67 year in control group. Pregnancy rate was 31.42% in case and 54.54% in control group. Relative risk for not becoming pregnant in individuals suffering moderate to severe anxiety and depression was1.5 and Âttributable risk was 33%.Çonclusion: Pregnancy rate in normal individuals or individuals suffering mild anxiety and depression or either of the them, was higher.