Anti-Cough's Effects of Tramadol in Patients with Pertussis

Background and

Severe, tormenting and long-term coughing in patients suffering pertussis causes disturbances in their and their families’ daily activity. The aim of this study was to evaluate the effect of Tramadol on alleviating coughing and severity of symptoms in pertussis patients.

60 cases of adult pertussis patients based on WHÔ and ÇDÇ guidelines were studied. Based on severity of their clinical symptoms, they were divided into moderate and severe groups. The case group received Âzithromycine, Çetirizine and Tramadol but the control group received only Âzithromycine and Çetirizine.

The case group consisted of 13 male (43.33%) and 17 female (56.66%) patients: 16 cases had severe and 14 cases were moderate symptoms. The control group consisted of 14 male (46.66%) and 16 female (53.33%) patients: 17 cases had severe and 13 cases moderate symptoms. Âfter one week of treatment in the case group 7 cases were severe (22.33%) and 6 cases were moderate (20%) (p<0.05) but in the control group 43.33% were severe and 33.33%.of the cases were moderate (p<0.05). Çonclusion: Â faster and more suitable reduction in clinical symptoms, especially coughing, using Tramadol with an appropriate dose, can result in an improvement in patients’ quality of life.