Investigating the Response and Adaptation of Interleukin- 15 to Resistance Training of Untrained Young Men

Scientific findings show that interleukin-15 is a key factor in muscular hypertrophy and is known as a factor stimulating the growth of skeletal muscles. The purpose of this study was to determine the response and adaptation of interleukin-15 to resistance training of untrained young men. In order to conduct the study, 20 young men were randomly chosen and divided into two groups of experimental (n=12, weight of 65.2±10.71 kg) and control (n=8, weight of 59.8±11.4 kg). The experimental group performed resistance exercise 3 times per week for 8 weeks. This program consisted of 8 exercises, 3 sets, and each set 10 repetitions with 70% 1RM. The first blood sample was obtained before training and after 12- hour fasting. In order to assess the response, the second and third blood samples were obtained immediately one hour after the completion of the first resistance exercise session whichwas performed once with 70% 1RM. The last blood sam- ple was obtained after 8 weeks of exercise to assess the adaptation of the exercises applied to both experimental and control group with the same condition. The Data was analyzed by Kolmogrov-Smirnov test, repeated measure, post hoc tests of least significant difference (LSD) and t test. The results showed that there was not significantly difference between experimental and control groups regarding critical and delayed response of IL-15 on resistance training (p≥ 0.05).There was also no significantly difference between experimental and control group regarding the adaptation in resistance training(p≥0.05). But after 8 weeks of resistance training the strenght average of the experimental group increased significantly from that of control group(p≤0.05), and the cause of this increase probably could be related to biochemical adaptation and nervous system and it had nothing to do with changes in plasma levels of IL-15.