Clinical and radiographic evaluation of the effect of bovine-derived hydroxyapatite (Bio-Oss®) and a synthetic HA/β-TCP (Osteon®) in the treatment of class II furcation defects in mandibular molars

Background and aims. There are some studies comparing bone replacement grafts. The aim of this study was clinical evaluation of the effect of Osteon® (as a new bone material) and Bio-Oss® (Bovine-derived hydroxyapatite) in the treatment of mandibular molar class II furcation defects in humans.Materials and methods. Eleven patients (10 females and 1 male, age range of 27-59 years; mean age of 45.5±11.8 years) who had at least 22 mandibular class II buccal or lingual furcation defects were treated either with Osteon (as the case group) or Bio-Oss (as the control group). Each defect was randomly assigned to either the case group or the control group. Clinical parameters and the soft tissue and hard tissue measurements, including plaque index (PI), gingival index (GI), gingival recession of furcation area (GR), pocket depth (PD), clinical attachment level (CAL), horizontal defect depth (HDD), vertical defect depth (VDD) were recorded at baseline and six months after surgery. Data were analyzed using t-test or Wilcoxon's test.Results. Similar healing results were observed for both treatments. The results showed significant probing depth reduction (case group: 0.77 mm and control group: 0.84 mm) and HDD reduction (case group: 0.51 mm and control group: 0.8 mm) and PI reduction. There was not statistically significant difference between the groups in all soft and hard tissue parameters.Conclusion. The results of this study showed that the effect of using Osteon as a bone graft material is the same as that of Bio-Oss in the treatment of mandibular class II furcation defects.