Evaluation of Frequency of Clinical and Pathological Findings in Lung Diseases in Shahid Sadoughi University of Medical Sciences of Yazd, during 2001-2006

Introduction & The pulmonary diseases which are the most common diseases are categorized into two groups of Non Neoplastic and Neoplastic diseases. Non neoplastic diseases are tuberculosis, pulmonary fibrosis, inflammatory lung diseases, vasculitis and pneumoconiosis. Neoplastic diseases are Bronchogenic carcinoma such as squamous cell carcinoma (SCC), adenocarcinoma (AC) and lung metastatic lesions. With high prevalence and similarity of clinical signs, histopatology is helpful in diagnosis of diseases. The aim of this study is evaluation of frequency of clinical and pathological findings in lung diseases in Shahid Sadoughi University. This study was descriptive and retrospective and it involed 400 lung samples (200 samples Non Neoplastic lesions and 200 samles of Neoplastic lesions) who referred to Shahid Sadoughi, Shahid Rahnemoon and Afshar hospitals of Yazd, Iran, in the time interval 2001-2006. The information including diagnosis by biopsy, age, sex, clinical signs and diagnosis before biopsy, were filled out and data was analyzed by chi-square. From 400 cases 273 were males (68.3%) and 127 females (31.7%), From 200 of Non Neoplastic lesions, TB was 39.9%, pneumoconiosis 27%, pulmonary fibrosis 23%, Vasculitis 6%, inflamatory lung diseases was 5% and of 200 Neoplastic lesions, primary lung Neoplastic lesions was 56.5% and lung metastatic lesions 12.5%. All lesions were more common in men than women and more common in ages over 60 years (except for vasculitis). The most clinical features were cough and dyspenica (except for vasculitis). The most common type of Neoplastic lesions were SCC (22.5%) and AC (23.5%). 1- All lesions were more common in men. 2- All lesions were more common in age more than 60 years except for vasculitis. 3- Cough and dyspenica were the most clinical findings. 4- The most common type of Neoplastic lesions were SCC (22.5%) and AC.