|تاریخ چاپ: 1399/09/04|
|Mean Platelet Volume and Red Cell Distribution Width as a Diagnostic Marker in Acute Appendicitis|
|Author(s):||Ceren Sen Tanrikulu، Yusuf Tanrikulu، Mehmet Zafer Sabuncuoglu، Mehmet Akif Karamercan، Nezih Akkapulu، Figen Coskun|
BackgroundAcute appendicitis (AA) is one of the most common causes of emergent surgeries. Many methods are used for its diagnosis.
ObjectivesThis study was conducted to investigate the diagnostic value of MPV and RDW in acute appendicitis.Patients and
MethodsThis study was a retrospective multi-center cross sectional planned study. The study included 260 patients operated for AA and 158 patients as the control group. Groups were compared in terms of MPV, RDW, white blood cell count (WBC), neutrophil predominance (NP) and platelet count (PC).
ResultsMPV was significantly lower in AA group, compared to the control group (P < 0.001). The best cut-off level for MVP in AA was ≤ 7.3 fL and the sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and overall accuracy ratio were 45%, 89.2%, 87.3%, 49.6% and 61.7%, respectively. There was no significant difference between the two groups in terms of RDW and platelet values.
ConclusionsMPV is a routinely measured parameter in complete blood count (CBC) and requires no additional cost. It significantly decreased in AA, having a greater sensitivity and NPV when combined with WBC and NP.
|Keywords:||Appendicitis، Erythrocyte Indices، Blood Platelets|
|Published:||Iranian Red Crescent Medical Journal, Volume:16 Issue: 5, 2014|
|Full text:||PDF is available on the website.|