فهرست مطالب

Traditional and Integrative Medicine - Volume:1 Issue: 1, 2016
  • Volume:1 Issue: 1, 2016
  • تاریخ انتشار: 1395/01/09
  • تعداد عناوین: 8
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  • Hossein Rezaeizade Pages 1-2
  • Malihe Safavi, Mohammad Reza Shams, Ardakani, Maryam Sadat, Seyedbagheri, Alireza Foroumadi Pages 3-17
    Peptic ulcer and gastritis are common and universal disease which affect up to 50% of the world’s adult population. Helicobacter pylori is a major cause of chronic-active gastritis and primary duodenal ulcers, and is strongly linked to gastric cancer. H. pylori induce chronic gastritis in virtually all infected patients. Chronic gastritis induced by H. pylori increases the risk for a wide spectrum of clinical outcomes, ranging from peptic ulcer disease and atrophic gastritis to gastric adenocarcinoma and gastric mucosal lymph proliferative diseases. Extracts of several plants including Cinnamomum zeylanicum, Coriandrum sativum, Malus domestica, Phyllanthus emblica, Pistacia lentiscus, Portulaca oleracea, Punica granatum, and Terminalia chebula have been used in Iranian traditional medicine as therapeutic agents for gastritis and peptic ulcer diseases. The information on all of these remedies was derived from all available old sources such as traditional books. According to new database the mechanisms of action for some of these plants are known. For example T. chebula causes improvement in the secretory status of Brunner’s gland and also, aqueous extracts of this plant have anti-bacterial activity against H. pylori. The information of more recent studied Iranian folk medicinal plants such as Camellia sinensis, Geum iranicum, Rheum ribes, Salvia mirzayanii, Sambucus ebulus, Stachys lavandulifolia, Stachys setifera, Trachyspermum copticum, and Zataria multiflora are presented in this review. The medicinal properties of these folk plants are attributed mainly to the presence of natural anti-oxidants and potent anti H. pylori activity. It is suggested that an evaluation of the effects of these plants on different aspects of gastric disorders should be performed and further studies are necessary on the other traditional and folk medicinal plants of Iran.
    Keywords: Traditional Medicine, Gastritis, Peptic Ulcer, Helicobacter pylori, Iran, Medicinal Plant
  • Nastaran Ebadi, Fatemeh Masoomi, Maryam Yakhchali, Seyedenargess Sadati, Lamardi, Mohammadreza Shams, Ardakani, Omid Sadeghpour, Azadeh Raiesdana, Farid Ramezany Pages 18-27
    Similar to other traditional medicines, Traditional Persian Medicine (TPM) applies its special terms for description of drug functions. Among these functions, convoy (Mobadregh) medicines are unique, mainly due to the interaction of them with the pharmacokinetics of other herbal medicines. These interactions suggest the potential herb-herb and herb-synthetic drug interactions with convoy medicines that necessitate the study and precise definition of them. For this purpose, old Persian medical texts and pharmacopeias were searched and investigated for the name of convoys, their target organ(s), primary qualities, and other functions. Relationships among convoy and other functions based on notes on the texts and statistical analysis were considered. Based on the old resources, the convoys were defined as modifiers (of drug actions), which facilitate access of drugs and foods to whole body or organs. The concept of targeting in some convoys was also implied as well as other disciplines such as Traditional Chinese Medicine and Ayurveda. Descriptive analysis of the available data showed that most of the convoys contain warm and dry primary qualities. Anti-blockage and thin consistencies are main characteristics of this class of drugs. Statistical analysis also showed diuretic activity is another major characteristic of them. Other functions such as discutient, attenuant, and tonic are capable to assist convoying by thinning of humors and organs. Analysis of TPM literature shows the presence of a logic approach in the formulation of compound drugs. Owing to the potential influence of convoys on the pharmacokinetic profile of other herbs and synthetic drugs, it is necessary to conduct future studies to evaluate these interactions in TPM and modern medicine.
    Keywords: Traditional Persian Medicine, Materia Medica, Herbal Drug Interactions, DrugFunctions, Drug Targeting, Bioavailability
  • Bahram Delfan, Mahmoud Bahmani, Hossein Kazemeini, Arman Zargaran, Mahmoud Rafieian, Kopaei, Majid Asadi, Samani, Somayeh Shahsavari Pages 28-34
    In the recent decades, hyperlipidemia has considerably increased with the development of machine life. It has been accompanied by diseases such as hypothyroidism, liver and kidney diseases, diabetes, chronic kidney disease, as well as obesity and can cause complications such as atherosclerosis, hypertension, increased risk of stroke, and fatty liver disease. Lorestan province in the west of Iran has an ancient history in traditional medicine and abundance of medicinal plants. So, this study aimed to identify effective medicinal plants for hyperlipidemia in this province and report its effects on the treatment of hyperlipidemia and the related diseases. This study was conducted during 2008-2010 by 11 trained health volunteers with the cooperation of Food and Drug Chancellor, Razi Herbal Medicine Research Center, and Health and Treatment Networks of Khorramabad, Dorud, Poldokhtar, Boroujerd, Aleshtar, Aligoodarz, Kouhdasht, and Noorabad. Questionnaire method was used, and a specific questionnaire was designed to gather information on traditional herbal therapy, which has been used to reduce hyperlipidemia in this province. The results of the questionnaire analysis indicated that in lorestan province, nine species of medicinal plants from eight plant families were used for treating hyperlipidemia. Leaves were mostly used plant part (42%) and predominantly used herbal preparations were raw plants (46%). Summer with 38% of frequency was the most reported season for collecting medicinal plants effective for hyperlipidemia in this province. Cichorium intybus was the most frequently used medicinal plant (73.33%). Novel scientific studies support the ethnomedicinal use of some of the mentioned plants in the lorestan province of Iran for the treatment of hyperlipidemia. However, further clinical investigations are needed to confirm their efficacy and safety.
    Keywords: Persian Medicine, Hyperlipidemia, Medicinal Plants, Ethnobotany, Lorestan, Iran
  • Masumeh Mobli, Ismaeil Haririan, Gholamreza Amin, Mohammad Kamalinejad, Mannan Hajimahmoodi Pages 35-39
    Myrtus communis L. is a medicinal herb that widely used in Iranian traditional medicine. Myrtle leaves extracts have been studied and a variety of products made from myrtle leaves in Iran and other countries, but only recently, the berries have been the object of scientific interest. In this study, we prepared herbal syrup from myrtle berries aqueous extract and standardized based on total phenols (Folin-Ciocalteu method) and gallic acid (Rhodanine assay) content. Stability tests including phytochemical assay and microbial limit tests were conducted during 3 months of the storage period and pH and viscosity variation of the product were recorded. pH and viscosity of syrup have not been significant changes during 3 months of storage. Evaluation of polyphenol and free gallic acid in myrtle berries syrup was investigated showing that myrtle syrup is microbially and phytochemically stable in the initial 3 months of the storage period.
    Keywords: Myrtus communis, Myrtle, Phenolic Compounds, Gallic Acid, Syrup, Traditional Medicine
  • Kolavanahalli Pillegowda, Smitha, Kuruba Srinivas, Kulashekar, Thotlaganahalli Krishnappa, Pavithra, Bagepalli Srinivas, Ashok, Kumar, Gopi Setty, Saran Pages 40-43
    Sitopaladi Churna is an ayurvedic formula, traditionally used as anti-inflammatory, carminative, sedative, expectorant, anti-infective, and various respiratory disorders. The aim of the present study is to screening for alpha amylase (α-amylase) inhibition activity of aqueous extract of Sitopaladi Churna. In vitro α-amylase inhibition activity of Sitopaladi Churna was screened by the 3,5-dinitrosalicylic acid method. Sitopaladi Churna showed potent (α-amylase) inhibitory activity with an IC50 - 46.38 µ g/ml. Thus, Sitopaladi Churna may consider as a remedy for diabetes and other insulin resistance-related diseases; however, animal and human studies are needed to confirm this activity.
    Keywords: Sitopaladi Churna, Ayurvedic Formula, Diabetes, Alpha Amylase, Dinitrosalicylic Acid
  • Nassim Rahmani, Zohreh Heydarian Pages 44-46
    Salicornia is one of the halophyte plants that grow in salt marshes and beaches. The aim of the present study is to evaluate the in vitro antifungal activity of Salicornia iranica, an endemic species of Iran, in two fungal species, including Aspergillus niger and Candida albicans. For this purpose, S. iranica 70% of ethanolic extract was prepared and mixed in plates with agar medium containing A. niger and C. albicans separately and allowed to gelatinize. Fungal samples were placed on each plate by the sampler. After absorption of microbial suspension into the agar plates, all of them were incubated at 25 °C for 72 hours. The results showed that S. iranica has no inhibitory effect on tested fungi. Since the antimicrobial activity of Salicornia have been attributed to fatty acid methyl esters, negative antifungal activity may be due to the lack of this compound in ethanolic extract, degradation of them through extraction, or the resistance of tested fungal species to the related compounds.
    Keywords: Salicornia Iranica, Antifungal Activity, Ethanolic Extract, Aspergillus Niger, Candida, Albicans
  • Soodabeh Bioos, Esmail Nazem, Mansoor Keshavarz, Marziehbeigom Siahpoosh, Farnaz Sohrabvand, Hamid Sohanaki, Fatemeh Nejatbakhsh Pages 47-51
    Infertility is defined as the inability to conceive after 12 or more months of regular intercourse without contraception. Sperm abnormalities are introduced as 20-47% of infertility etiology. Idiopathic male subfertility is common (40-50%). In the Iranian traditional medicine, many natural drugs are used for enhancing fertility. This case series was an effort to understand the role of an Iranian traditional formulation in conception. For this purpose, 13 men with infertility and idiopathic oligoasthenoteratospermia were treated by 10 g Majoon-e Loboob twice daily. 11 (84.6%) of their wives became pregnant after 4.8 ± 2.0 months. In men with severe oligoasthenospermia (
    Keywords: Iranian Traditional Medicine, Male Infertility, Majoon, e Loboob, Sperm Parameter, Natural Remedy