فهرست مطالب

مجله علمی پزشکی جندی شاپور - سال چهاردهم شماره 1 (پیاپی 99، 1394)
  • سال چهاردهم شماره 1 (پیاپی 99، 1394)
  • ویژه نامه 1394
  • تاریخ انتشار: 1395/01/20
  • تعداد عناوین: 12
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  • Mahmoud Jahangirnezhad, Saede Atarbashi Moghadam, Sepide Mokhtary, Ali Lotfi, Fateme Taghizade Page 1
    Background And Objective
    Head and neck squamous cell carcinoma is frequently associated with synchronous or metachronous malignancies. The development of a second malignancy is almost always fatal¡ thus careful screening programs and long follow up should be considered in these patients. This article describes a case of adenocarcinoma of lung that was discovered in a patient with oral squamous cell carcinoma.
    Keywords: Squamous Cell Carcinoma, Adenocarcinoma, Second Malignancy
  • Fatemeh Asareh, Mohammad Gachkooban, Ahmad Dastani, Maryam Zarei Page 9
    Background And Objective
    BCL-2 is the first gene involved in apoptosis and was regarded as a proto-oncogene that suppresses the cell death rather than stimulating cell proliferation. The present study was conducted to assess and compare the immunohistochemical expression of BCL-2 in selected benign (Pleomorphic adenoma) (PA) and (adenoid cystic carcinoma and polymorphous low grade adenocarcinoma) (ACC¡ PLGA) salivary gland tumors.
    Materials And Methods
    In this in vitro study seven ACC and three PLGA tumors were considered as malignant and 17 PA as benign tumors. The immunohistochemical staining procedure was performed using BCL-2marker¡ as directed by the manufacturer. Results were assessed in percentage of cells stained in 0-3 [0(negative)¡ 1(1%-30%)¡ 2(31%-70%)¡ 3(71%-100%)] scores.
    Results
    All malignant tumors showed a positive expression for BCL-2whereas only %58 of benign tumors was positive. Statistical significance was observed with regard to BCL-2expression in benign and malignant tumors. In findings of this study no relationship between BCL-2expression with independent variables such as age¡ sex¡ and the origin of the lesion was found.
    Conclusion
    According the results of the present study greater expression of BCL-2in malignant salivary gland neoplasm suggests a higher survival rate of tumor cells in malignant tumors. It seems that BCL-2 is not a suitable marker to differentiate various salivary gland tumors from each other.
    Keywords: BCL, 2, salivary gland tumor, Pleomorphic adenoma, immunohistochemical stain
  • Sanaz Sharifi Shoshtary, Maryam Khani, Aminollah Omidy Norabady, Negin Khosravi, Saghar Harandi Page 21
    Background And Objective
    Accurate working length determination of root canal is always considered by dentists. Radiographic techniques that commonly used in root canal therapy are periapical conventional techniques¡ but digital radiography has been of great interest in recent decades. This study aimed to compare the accuracy of conventional and digital radiography in measuring the working length of the canal.
    Materials And Methods
    This experimental in vitro study conducted on 58 individuals molar teeth of the maxilla. After selecting the teeth¡ mounting in acryl¡ cavity preparation and inserting k-file number 15 in the canal¡ conventional and digital periapical (PSP) radiography has been taken of teeth. Then¡ the values of the working length of the canal which were obtained from three methods¡ digital radiography¡ conventional radiography and real values were compared. Data analyses were performed using SPSS Ver.19.
    Results
    A significant difference was found between the working length which is measured by conventional method and the real working length (p 0.124). Also¡ there was a significant difference between the working lengths measured by conventional radiography versus digital radiography (p
    Conclusion
    Digital radiography had greater accuracy in estimating the working length of the canal versus conventional radiography.
    Keywords: Working length of the canal, Digital radiography, Conventional radiography
  • Arash Dabbaghi, Arman Feiz, Hojatollah Yousefimanesh, Maryam Robati, Hadis Yousefimanesh, Narges Ezati Givi Page 29
    Background And Objective
    The sinuses are empty holes that placed within the face bone. The internal surfaces of sinuses are covered with mucous membranes. The paranasal sinuses are approximate to anatomical proximity and its disease can spread to the cranial cavity. The purpose of this study was to evaluate the maxillary sinus floor mucosal thickening of patients referred for cone beam computed tomography (CBCT).
    Materials And Methods
    This retrospective study performed on 161 patients tomography (80 females and 81 males) referred to a specific radiographic center for taking CBCT imaging tomography for treatment including implant insertion at maxillary sinus site and situation that sinus were seen evaluated. All evaluation registered by two examiners in a monitor and same position. Chi-square test was used to investigate the relationship between two variables.
    Results
    The highest percentage of patients referred to radiographic center was aged 51-60(64.5%) and the lowest percentage was 7180 years old (3.7%). A total of 64.6 % of samples had bilateral increase mucus and 11.2 had unilateral increased mucus. The prevalence of thickening sinus mucosa in men were more than women (P=0.016). According to the CBCT images the highest prevalence of maxillary sinus floor mucosa increase was observed in May (17.4%) and the lowest increase was observed in December (5%).
    Conclusion
    The increase of maxillary sinus floor mucosa was associated with age¡ sex¡ and monthly visit.
    Keywords: Cone beam computed tomography, Maxillary sinus, Increase of mucosal thickness
  • Mahmoud Jahangirnezhad, Bizhan Keikhahi, Hojatollah Yousefimanesh, Gholamhossein Taheri, Mina Zaheri Abdehvand Page 37
    Background And Objective
    Hemophilic patients in Ahvaz have received minimal dental treatment and they need required consideration. The purpose of present study was to assess and compare periodontal and dental status of patients with hemophilia A of Ahvaz Shafa hospital in 2011-2012.
    Materials And Methods
    The present study was a case control study carried out on patients with hemophilia A of Ahvaz Shafa hospital. Following clinical examinations¡ the plaque index indicators¡ DMFT and CPITN index were recorded for case and control groups. In addition¡ a questionnaire including personal information was completed.
    Results
    In the present study there was a significant difference between patients and control group in DMFT. The decayed¡ filled and extracted teeth in hemophilia patients were significantly higher than the control group.
    Conclusion
    According to the results of the present study it seems that preventive and therapeutic dental services for patients with hemophilia A of Ahvaz Shafa hospital is far from optimal level. Thus¡ the results of this study could be used in the preventive and therapeutic principles planning.
  • Nasim Shams, Arash Dabbaghi, Sanaz Sharifi Shushtari, Soheila Bayati, Azam Moazampur Page 43
    Background And Objective
    Nowadays¡ the use of CBCT is expanded due to its benefits to conventional radiographies in evaluation of maxillofacial region. The aim of this study was the evaluation of appearance¡ location and course of the mandibular incisive canal with Cone Beam Computed Tomography (CBCT).
    Materials And Methods
    This retrospective study included 100 CBCT examinations. The examinations were taken using the planmeca promax 3D unit and exposure setting of 84 kVp¡ 12mA. The acquired images were processed with the Romexis software (version 2.8.1). Three oral radiologists evaluated the visibility of the incisive canal¡ independently. The distances of the incisive canal to the buccal¡ lingual and lower border of mandible and canal length were measured in right and left side in origin and terminal point of incisive canal. Data were analyzed by t-test¡ chi square test and Cohen’s kappa correlation.
    Results
    The mandibular incisive canal was definitely visible approximately in 84% of the CBCT images. The mean distances from the buccal¡ lingual and inferior border of the mandible in original point of canal were 2.02mm¡ 4.04mm and 8.96mm¡ respectively. These were 3.02mm¡ 3.68mm¡ 7.86mm in terminal point of canal¡ respectively. The mean length of the canal was approximately 8.7mm. The canal was running from the mental foramen toward the symphyseal region in downward and lingual direction.
    Conclusion
    CBCT imaging is recommended for evaluation of mandibular incisive canal in anterior region of mandible before surgical procedures such as insertion of implants and bone graft.
    Keywords: Cone Beam Computed Tomography, Mandibular, Anterior, incisive canal
  • Mohammad Yazdizadeh, Ali Rezaee, Ali Jahangirnezhad Page 53
    Background And Objective
    Gutta percha is a common material used filling root canal and recently made with various tapering. The aim of present study is evaluating the effects of tapering of master cone on marginal adaptation of curvature canal prepared using nickel- titanium rotary instruments.
    Materials And Methods
    in this in vitro study 45 mandibular molar teeth selected with two canals and separated apical foramen while curved more than 20 degree based on using (%2¡%4¡%6) master cone taper¡ then divided in three experimental groups of 15. After preparation with %6 of rotary files to 30 apical areas¡ the root filled by cold lateral condensation technique and AH plus sealer¡ and from each sample¡ four section of 1mm were cut from the apex by sectioned instrument and used SEM for investigation. The data were analyzed using variance analysis (ANOVA) and Kurskal- Wallis test in significant level P
    Results
    After observation under SEM¡ the mean area of space in group A filled with %2 taper found significant difference between sections where the smallest in the first section and the largest space was in the third section¡ and difference in group B filled with %4 taper were significant between sections where the largest area of space was in the second section and smallest in third one. The difference in group C filled with %6 taper was not significant: the largest area of space was in the second section and smallest in first one.
    Conclusion
    According to the finding of present study using various taper of gutta percha for filling including %2 taper gutta percha is superior to marginal fitting in the end of apex required apical seal.
    Keywords: Rotary instrument, Marginal adaptation, Gutta percha, Sealer
  • Fatemeh Asareh, Hojatollah Yousefimanesh, Maryam Robati, Fatemeh Salehi Ghale Sefid, Peyvand Taherzadeh Page 63
    Background And Objective
    Wound healing is influenced by many internal (pathophysiological) and external (microorganisms and drugs) factors. The purpose of this study is the histological comparison of the effect of using edible honey and phenytoin in healing the hard palate wounds in rats through a pilot study.
    Materials And Methods
    A total of 45 Wistar rats with an approximate weight of 200± 10 were randomly divided into three groups. The surface of the hard palate was cut transversely with dimensions 6 × 4 mm under general anesthesia. Treatment was started the day after surgery¡ so that the first group received oral phenytoin and the second one honey and the third group was considered as control. For histopathological studies on days three¡ seven¡ and 14 after surgery¡ 3 groups out of 3 categories were killed and biopsied and then slides were prepared from the wound site. Then¡ the size and persistence of newly formed epithelium¡ number of newly formed vessels¡ lymphocytes¡ neutrophils and collagen levels were investigated.
    Results
    The maximum amount of neutrophil (acute inflammation) on the third day in edible honey group had statistically significant difference compared to the seventh day (P = 0.010). Also¡ the maximum level of lymphocytes (chronic inflammation) on the third day had statistically significant difference compared to fourteenth day (p = 0.005). The highest rate of collagen was on day 14 in edible honey group. The maximum vascularization had been on the seventh day in phenytoin group¡ but this process was declining from the7th to 14th day¡ but the difference was not statistically significant. Quantities and qualitative data were analyzed by ANOVA and Kruskal Wallis¡ respectively.
    Conclusion
    The oral honey can be effective in wound healing by reducing inflammation¡ increasing the tissue collagen and increasing re-epithelialization. However¡ it seems that the use of oral phenytoin has no significant impact.
    Keywords: Histological comparison, Honey, Phenytoin, Wound healing, Hard palate
  • Tavakol Khanizadeh, Saeed Shirafkan, Amirali Badri, Babak Javidi, Mahshid Razavi, Vahid Noorolahi Fard Page 79
    Background And Objective
    The management of orbital fractures is one of the most interesting areas in facial trauma. No consensus exists on the choice of implants which is used for orbital floor reconstruction. Here we present the short term results of the outcome of ramus autogenous graft versus alloplastic materials in a randomized prospective clinical trial.
    Methods and
    Methods
    A total of 22 patients with orbital floor fracture were entered to our study in two groups¡ randomly. Patients of first group were treated by autograft of lateral cortex from mandibular ramus¡ and the patients of second group by titanium mesh as an alloplastic material. All patients were followed for six months and enophthalmos¡ diplopia¡ cheek paresthesia and infection rate were assessed.
    Results
    There were no significant difference between two groups (P value = 0.66). Both mandibular ramus and alloplastic titanium mesh can be used in orbital floor reconstruction regardless of size of defect.
    Conclusion
    Both mandibular ramus autograft and alloplastic titanium mesh are reliable and successful techniques to address the orbital floor fracture. Ramus region provides an appropriate volume of bone with vascularization¡ low extrusion rate and inert¡ but donor site morbidity and more time-consuming are disadvantages. Highly biocompatibility¡ minimal resorption potential¡ wellrecognized osseointegration and contouring¡ no donor site morbidity and less time consuming are advantages of titanium mesh¡ but its disadvantages include the risk of graft extrusion or anticipated difficulty while insertion and removing the material if needed because of fibrous ingrowth and also additional cost requirement .
    Keywords: Orbital floor fracture, Autograft, Alloplast, Ramus
  • Mahmoud Jahangirnezhad, Morvarid Mafi, Peyman Zia, Rahil Mirzaei, Erfan Safikhani Page 89
    Background And Objective
    Periodontitis is an inflammatory disease that destructs the dental attachment apparatus. Interleukin18 is an effective pro-inflammatory cytokine in destruction of periodontium. Since smoking is an important risk factor for periodontitis¡ this study was designed to evaluate the effect of smoking on levels of salivary IL-18 in smoker and non-smoker individuals with either healthy periodontium or periodontitis.
    Materials And Methods
    A total of 18 individuals referred to dental clinic were divided into four groups (n=20) (Non-smoker with healthy periodontium¡ non-smoker with periodontitis¡ smoker with healthy periodontium¡ and smoker with peridontits). Bleeding on probing¡ clinical attachment loss¡ probing pocket depth and plaque index were registered for each group. Salivary sampling was performed and levels of IL-18 were measured by means of an enzyme-linked immunosorbent test. Data were analyzed by one way ANOVA¡ Tukey test¡ t-test and chi-square test. P
    Results
    The results showed a significant differences in the above mentioned clinical parameters and levels of salivary IL-8 among groups (P
    Conclusion
    According to the present study it seems a significant increase occurs in levels of salivary IL-18 in individuals with periodontitis¡ but the effect of smoking on IL-18 levels is minor and non-significant.
    Keywords: Chronic periodontitis, Interleukin, 18, Smoking, Saliva
  • Mahmoud Jahangirnezhad, Morvarid Mafi, Peyman Zia, Hojatollah Yousefimanesh, Hadis Jalalvand Page 99
    Background And Objective
    The traditional diagnosis methods have been considered efficient to distinguish between active and non-active states of Periodontitis. These indicators will provide information about the severity and extent of disease rather than on the current activity of the disease. The present study was a guideline to determinate the effect of elastaese in salvia before and after treatment of periodontal disease.
    Materials And Methods
    This clinical trial study was performed on the chronic periodontitis. Full-mouth bleeding on probing (BOP)¡ probing depth (PD)¡ Plaque index (PI)¡ clinical attachment loss (CAL) and salivary elastase were recorded from all patients before and after six weeks of treatment (first phase of periodontal therapy). The levels of elastase were determined by an enzyme-linked immunosorbent assay.
    Results
    The results demonstrated significant differences in the above mentioned clinical parameters and levels of salivary IL-8 among study groups (P
    Conclusion
    The levels of elastase in saliva before treatment were higher than post treatment. Therefore¡ periodontal disease seems to be related to higher levels of elastase in saliva.
    Keywords: Chronic periodontitis, Elastase, Scaling root planning, Salvia
  • Soheyla Bayati, Negin Khosravi, Mastoreh Yosefi, Maryam Khani, Makan Dadollahi Sarab, Paarastoo Jafari Page 107
    Background And Objective
    Removal of third molars in dental surgery is one of the most common practices and knowledge of the pattern of impaction and associated pathology which can help to prevent some specific problems. The purpose of this study was to evaluate the status of third molar impaction and associated pathology in panoramic radiography in patients referring to the Radiology Department of Ahvaz dental school in 2013-2014.
    Materials And Methods
    descriptive and cross sectional study was performed on the 503 third molar of 252 patients with impacted third molar referred to the radiology department. Panoramic machine (Sordex) was used for All of the panoramic radiographs and panoramic were evaluated by one observer on the monitor. SPSS ver. 20.0 and Chi-square test were used for data analysis.
    Results
    The prevalence of impaction in patients was 40% in men and 60% women. 54% of the impacted teeth were in the mandible¡ and 46% in maxilla. 20/4% of the teeth had lesions (48/54% in males and 51/46% in females). 69% of lesions were in the mandible and 31% in the maxilla.
    Conclusion
    The Prevalence of impaction was more prevalent in women and there was a significant relationship between gender and impaction. Type of impaction and the level of impaction were significantly associated with the prevalence of involved jaw. The prevalence of impaction was not associated with its location. The type of pathology is not associated with the age and gender.
    Keywords: Third molars, Impaction, Prevalence, Pathology