مجله دانش و تندرستی در علوم پایه پزشکی
سال یازدهم شماره 2 (تابستان 1395)

Post traumatic growth comes in some individuals that several psychological factors can affect in formation it. So because post traumatic growth in hepatitis B has not been studied, this study concerned with investigation of the causal relationship between personality traits and post traumatic growth with mediating role of cognitive emotional regulation in patients with hepatitis B.
The statistical society of this research was patients with hepatitis B in research center of Shiraz Namazi hospital. 165 patients with hepatitis B randomly selected and cloninger personality, garnefski cognitive emotional regulation and post traumatic growth questionnaire were used. Software SPSS and AMOS and path analysis were used for data analysis.
Results indicated that personality traits of reward dependency, self-transcendence, self-directedness, cooperativeness, persistence, and cognitive emotional regulation have significant and direct effect on post traumatic growth that Beta coefficient related to these variables are in turn 0.082, 0.074, 0.064, 0.451, 0.081, and 0.380. Also results indicated that novelty seeking, harm avoidance, reward dependency, and cooperativeness effect on post traumatic growth via cognitive emotional regulation that Beta coefficient related to these variables are in turn 0.084, 0.067, 0.086, 0.141.
Personality traits in addition direct effect on post traumatic growth, effect on post traumatic growth via cognitive emotional regulation.

Daphne mucronata has anti-oxidant and anti -inflammatory properties and it can have a quick effect on the recovery of the skin wound and bruises. The purpose of this research was to study the effects of Daphne mucronata on the cure of rat skin.
This study included 45 male rats, which were treated in four different random methanol essences groups and a control group. They were treated for twenty two days. A circular cut was produced in the neck of the rats. The samples on the third, seventh, fourteenth and twenty second days after treatment were collected for microscopic analysis. The data were analyzed using Kruskal-Wallis and freedman by the SPSS software.
From a macroscopic point of view and based on the measurement of the surface of the scratches and wounds in the groups under study, the healing trend of the scratches and wounds was increased considerably, so that in the fourteenth day of the treatment, a full recovery of the wounds was obtained, and on the twenty second day, the cuts and bruises were fully cared. The results of this study also showed that on the fourteenth and twenty two days, there was a significant difference between the control and treatment groups (P The results of this research showed that the methanol essential made from the flower, stem and leaves of daphne mucronata is effective in the recovery of the skin wound and speed of the process of healing the skin bruises.

Helicobacter pylori is a well-known bacteria; it produces multiple and serious gastrointestinal diseases. Studies in Iran, The prevalence of Helicobacter pylori infection is Variable between 7. 7-80% in pregnant women. The present study aims at assessing the prevalence of Helicobacter pylori infection among Iranian pregnant women using a meta-analysis method.
According to purpose study, published articles in national and international journals were examined about prevalence of H. pylori infection among Iranian pregnant women. To achieve the related documentation, national and International databases include: Magiran, Iran medex, IranDoc, SID, Medlib, Embase, Scopus, Web of Science, Pubmed, Science Direct, Cochrane and the Google Scholar search engine no time limit to 2015 were searched by using standard keywords. Search, data extraction and quality assessment were independently carried out by two researchers. The data were combined using Random Effects Model through Meta-Analysis method by Stata software.
1605 subjects were studied in 22 studies. The prevalence of H. pylori infection among Iranian pregnant women was estimated as 45.9% (95% CI: 39.4- 52.5). Minimum and maximum of this range were related to the West (36.2%) and the South (61.5%).
The prevalence of H. pylori infection among Iranian pregnant women is high and similar Iranian general population, the preventive strategies should be carried out to control this infection.

The prevalence of obesity among children and adolescents around the world alarmingly are increasing. Regular exercise can reduce fat tissue and improve body composition. The aim of this study was the effect of the high intensity interval training (HIT) on plasma levels of TNF-a, IL-6 and lipid profile in overweight children.
The present study was semi experimental research that performed in Tehran at 2014 year. In this study, 32 overweight students 8 to 11 divided in the experimental (n=16) and control (n=16) group. High intensity interval training including 30 seconds with maximum speed and 5.1 minutes rest was performed for 8 weeks and 3 sessions per week. The six HIT workouts in the first week increased to 10 to last week. Blood samples were collected from venous blood of right hand 48 hours last session. ANCOVA test performed for compared of variable mean (α=0.005).
The results of the present study showed that 8 weeks HIT significantly reduced level of IL-6 (P=0.001), TNF-a (P=0.001) and lipid profile. On the other hand, there was insignificantly change in TG (P=0.777), LDL (P=0.071) and HDL (P=0.693).
The findings of this study showed that 8 weeks HIT reduces the plasma level of TNF-a and IL-6. Therefore, perform of high intensity interval training with observed necessaryw55 caution in obese children can have positive effects.

Umbilical cord derived mesenchymal stem cells (MSCs) are one of the best sources for cell-based therapies. MSCs reveal the neuronal morphology and expression of neuronal marker in differentiation conditions. The aim of the present study was to differentiate of MSCs into neuron-like cells using Activin A and nicotinamide.
Umbilical cords were cut close to the placenta and smaller pieces (2-4 cm) of umbilical cords prepared and Wharton's jelly extracted. MSCs were isolated by an explant culture method and surface phenotype of cells analyzed by Dako flow cytometry and the FlowJo software. MSCs were then induced for osteogenic and adipogenic differentiation. Cells were exposed to neuronal differentiation condition and treated with 20 μg / ml Activin A and 0.1% FBS for 3 days in RPMI,then with 10 mMnicotinamide, 2% B27 and 0.1% FBS for 7 days.
spindle-shaped MSCs were observed after 7-10 days of explants culture. Immunophenotype of cultured MSCs were positive for mesenchymal markers such as CD105 and CD90 but negative for hematopoietic markers such as CD34 and CD45. After MSCs differentiation to the osteogenic or adipogenic lineage, lipid droplets and calcium deposition were observed. The differentiated neural-like MSCs were appeared as pyramidal nerve-like cells with neuritis.
Some of th cells. During neuronal differentiation, axon and dendritic like process wereosbserved in some of Bipolar and mulipolarmulipolar cells. Furthermore direct synaptic like contacts were observed between cells.
The present study showed that Activin A and nicotinamide could induce differentiation of MSCs into neural lineage.

Step test is one of the indirect methods of measuring the maximum aerobic capacity. The stairs are designed with constant height in more step tests, that the biomechanical differences of height can cause a bias in the results. This study was conducted to determine the validity and reliability of the height adjustable step to step test.
The minimum and maximum step height, according to the relationship in the Francis step test method was determined, and then the step was made. Intra-class Correlation Coefficient (ICC) was used to evaluate the reliability of step, after testing in 2 times, with an interval of one week on a single group. Also the Pearson correlation coefficient was used to assess the validity of the step. All analyzes were performed using SPSS software in significant level of 0.05.
The results of the reliability test, with an ICC correlation coefficient equal to 0.886, has confirmed the reliability of the researcher made step. Also the validity of step has been approved (P˂0.001 and r=0.737).
The results showed that the researcher made step has a good reliability and validity to measure the amount of VO2max. These findings indicate that this tool can be used for measuring VO2max in different people.

The number and quality of published articles in scientific journals is one indicator of evaluation of faculty members and the research output of universities of medical sciences. This study was designed to evaluate the quantity and quality of published articles in the Journal of Knowledge and Health.
This descriptive study was conducted by census sampling. Twenty-three articles from the years 1386 - 1391 were investigated. A researcher-made checklist including: authors and titles, introduction, methods, results, discussion, references, overviews, abstract, cohort study and clinical trial were designed. Descriptive statistics and test methods were used for data presentation and comparison.
One hundred and seventy one articles were evaluated, and the average number of articles per issue was 7.5 ± 2 articles. The average time spent from receiving a paper until its acceptance is 4 months. All articles had been obtained from the original research work, and no review article or letters to the editor was found on the issues. There were ten randomized clinical trial studies. The most complete part of articles were titles and references also were most correct unit, while the weakest part of the them was discussion.
Results obtained from the study of journal of Knowledge and Health indicated that the journal has progressed in terms of quality over the years, but there were some shortcomings. Therefore, a set of recommendations is provided to improve the journal.

Happiness and joy as one of the most important human psychological needs, has always occupied the human mind, because of its effect on formation of human personality and in generally on the whole of human life and creation of cheerfull organization is a strategic need for its long term success. The aim of the study was to investigate the relation of happiness and performance of employees at Shahrood Medical Sciences University.
In this research, happiness in 10 key dimensions, including organizational learning, Self- disclosure, participation, organizational justice, positive thinking, flexible structure, meaning ful work, interesting work, security and interaction with colleagues, has been studied with the oxford happiness and hersey and gold smith questionnaire. Pearson correlation coefficient and multi linear regression statistical analysis is used for data analysis at software SPSS 19.
Results showed that there are significant correlation between organizational performance with participants with the correlation coefficient equal 0.87, interested in working (0.79), organizational learning (0.78) and justice whith (0.75), respectively, and the next rank is for happiness (0.73).
According to the results, managers must look for practical and functional strategies to increase the level of gappiness of employees in which their performance will be imprived.

Shoulder impingement syndrome is one of the causes of shoulder pain and improve of range of motion in muscles of scapula and rotator cuff have great importante in the treatment of this syndrome. Therefore the purpose of this study was to investigate the effect of 8 weeks selected exercise training on range of motion of the shoulder impingement syndrome. In this study, 24 non-athletes aged 35 to 55 years voluntarily participated and randomly divided into two experimental and control 12 person.
The experimental group participated in eight weeks training program (three sessions per week). While the control group did their daily activities. Descriptive statistics were used to calculate the mean and standard deviation. For determining the extent of changes within the group and between groups, was used dependent and independent t-test (P The results of study showed that selected exercises in the experimental group significantly increased range of motion in the shoulder and the pain was reduced compared to the control group.
The results indicate that the use of the exercise therapy can be an effective way for improve range of motion and decrease of pain in patients with shoulder impingement syndrome.

Pay attention to the psychological aspects of diabetic patints, especially self-efficacy, important and can be very usefull in the process of treatment of them. Peer education has many effects in facilitating and creating an environment atmosfere. This study was conducted to evaluate the effect of peer education on diabetes self-efficacy.
In this randomized control trial study, 70 diabetic patients who were in Firoozgar hospital in Tehran were recruited using the convenience sampling method. The patients were assigned randomly into two control and intervention groups. Patients in the intervention group were trained by peers during the two sessions, but the patients in the control group received only routine education. Data were collected by demographic questionnaire and diabetes management self-efficacy scale. Patients self efficacy were measured before the education and 2 months after the intervention. Descriptive and inferential statistics were used to analyze data by SPSS.
Mean diabetic self efficacy in both groups had no statistically significant difference in days of hospitalization (P: 0.2). Also differences in mean diabetic self efficacy between the groups two months after the intervention were statistically significant (P Peer education to patients who are hospitalized, can increase diabetic self efficacy. Therefore, it is recommended that, this educational approach used in ward.