فهرست مطالب

  • Volume:17 Issue: 9, 2016
  • تاریخ انتشار: 1395/08/05
  • تعداد عناوین: 5
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  • Zahra Yazdznpanahi, Zahra Beygi, Marzieh Akbarzadeh*, Najaf Zare Page 1
    Background
    Proper sexual function is an important factor that affects family strength. Recently, the issue of obesity and the influence of body mass index (BMI) on sexual function have received increasing research attention..
    Objectives
    This study aimed to investigate the relationship between sexual function and its domains with obesity and central obesity..
    Methods
    This cross-sectional study was conducted on 514 women aged 15 - 45 years who presented at Shiraz healthcare centers in 2014 - 2015. Simple random sampling was performed. Data were collected by applying the female sexual function index (FSFI), weight, and meter. The questionnaire consisted of 19 questions that evaluated six domains, as follows: sexual desire, arousal, lubrication, orgasm, satisfaction, and pain. Scores
    Results
    The mean age of the subjects was 30.9 ± 5.8 years. The mean score for BMI in people with sexual dysfunction was 25.5 ± 4.09, which was not statistically significantly different from those without sexual dysfunction. The mean score of central obesity was 0.75 ± 0.12 in people with sexual dysfunction; this was not statistically significant in comparison to those without sexual dysfunction. Among the female sexual function domains, only sexual desire (P = 0.05) and arousal (P = 0.02) had a significant correlation with BMI. There were significant relationships between waist-to-hip ratio (WHR) and sexual arousal (P = 0.04) and satisfaction (P = 0.02)..
    Conclusions
    The only significant relationships were found between sexual desire and arousal and BMI and between central obesity and sexual arousal and satisfaction..
    Keywords: Body Mass Index, BMI, Waist, to, Hip Ratio, WHR, Sexual Function, Women
  • Mahnaz Yadollahi, Asghar Razmjooei, Kazem Jamali, Mohammad Hadi Niakan, Zahra Ghahramani* Page 2
    Background
    Professional quality of life is the quality that everyone feels in relation to their work. Both the positive and negative aspects of doing a job influence the professional quality of life. The majority of people spend more time at work than they do anywhere else, doing anything else..
    Objectives
    The aim of this research was to study the relationship between professional quality of life and general health in the staffs of Rajaee trauma hospital..
    Methods
    This was a cross-sectional study, which was conducted at Rajaee trauma hospital of Shiraz during a 12-month period (2014). Participants were selected by systematic random sampling..
    Results
    We included 331 staff with mean age of 29.32 (5.1) years, amongst who there were 119 (36%) males and 212 (64%) females. Gender, marital status and education did not affect professional quality of life and general health, but emergency department personnel compared to other sectors had higher prevalence of depression and traumatic stress. In addition, the staffs were in good situation in terms of burnout, secondary traumatic stress, physical dysfunction, social dysfunction and severe depression and in moderate level in terms of compassion satisfaction and anxiety and sleep disorders..
    Conclusions
    The study findings confirmed a significant relationship between professional quality of life (ProQol) and general health questionnaire (GHQ)-28 dimensions. Reducing burnout and secondary traumatic stress as well as increasing compassion satisfaction had a direct impact on decrease in mental health problems in the staff..
    Keywords: Relationship, Professional, Quality of Life, ProQol, General Health, Iran
  • Mahboubeh Firouzkouhi Moghaddam, Tayebeh Rakhshani, Mohsen Khosravi* Page 3
    Background
    This study investigates the therapeutic effect of a combination of methylphenidate and a zinc, calcium, and magnesium supplement for the treatment of attention deficit hyperactivity disorder (ADHD) in a population of children from the city of Zahedan..
    Methods
    This clinical trial involved 40 patients with ADHD aged 6 to 12. Simple convenience sampling was conducted and the patients were randomly divided into two groups: a case group which received methylphenidate and a zinc, calcium, and magnesium supplement; and a control group which received methylphenidate plus a placebo. Numerical variables were presented as a mean (SD) and nominal and categorized variables were summarized by absolute frequencies and percentages. To compare the baseline measurements between the two groups, a chi-square test, an independent t-test, and a paired test were used. The data analysis was done using the statistical software SPSS, version 18.0..
    Results
    The mean age of the children in the case group was 9.6 ± 1.5 years and that of the children in the control group was 8.9 ± 1.6 years (P = 0.235). Of the children, 32 were boys (80%) and 8 were girls (20%) (P = 0.429). The mean for symptom severity in the case group was 40.4 ± 2.4 before treatment, and 19.5 ± 6.1 after 8 weeks of treatment (P
    Conclusions
    This study shows that a zinc, calcium, and magnesium supplement is effective in the treatment of ADHD..
    Keywords: Attention Deficient Hyperactivity Disorder, Methylphenidate, Magnesium, Zinc, Calcium
  • Rohollah Mousavidehmordi, Hossain Babaahmadi, Bita Shalbafan, Ghorban Mohammadzadeh, Mohammadreza Afsharmanesh, Alireza Kheirollah* Page 4
    Background
    Cholesterol homeostasis in the brain has been demonstrated in the pathogenesis of Alzheimer’s disease (AD). Experimental data support that brain cholesterol turnover can modulate central processes in AD pathogenesis. Excess cholesterol is eliminated from the brain via hydroxylation mediated by cholesterol 24S-hydroxylase (CYP46A1), a main mechanism of maintaining cholesterol homeostasis. The CYP46A1 gene has been suggested as a genetic risk factor for AD..
    Methods
    In this case-control study, we analyzed an intronic CYP46A1 gene single-nucleotide polymorphism (SNP) in 100 AD patients and 80 age- and sex-matched control subjects in the Iranian population..
    Results
    We found a significant difference in CYP46A1 TT-homozygotes genotype (χ2 = 5.06, df =1, P = 0.02) and T allele frequency (χ2 = 6.09, df = 1, P = 0.01) between AD patients and controls..
    Conclusions
    The results of our study indicate that intron T/C polymorphism of the CYP46A1 gene is associated with AD in the Iranian population, and that the CYP46A1 TT genotype or T allele frequency might be a genetic risk factor for AD and increase susceptibility to AD..
    Keywords: Alzheimer's Disease, CYP46A1 Gene, Single, Nucleotide Polymorphism, Brain Cholesterol Homeostasis
  • Nicola Ramacciati*, Laura Rasero Page 5