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Zahedan Journal of Research in Medical Sciences - Volume:19 Issue: 12, Dec 2017

Zahedan Journal of Research in Medical Sciences
Volume:19 Issue: 12, Dec 2017

  • تاریخ انتشار: 1396/11/15
  • تعداد عناوین: 5
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  • Farahnaz Farzaneh *, Mahdi Mohammadi, Abbasali Niazi, Arezoo Eamaeilzadeh, Soodabeh Rezaei Page 1
    Background
    To compare efficacy of pipelle biopsy as an office biopsy method with dilatation curettage (D&C) for women referring Ali Ebn e Abitaleb hospital of Zahedan university of medical science in 2015 - 2016.
    Methods
    In this cross sectional study, 200 patients with Abnormal Uterine Bleeding (AUB) who had referred to gynecology clinic of Ali Ebn e Abitaleb Hospital of Zahedan University of medical science, were selected. The patients were randomly allocated to the two groups based on permuted block design method. In 1th group (n = 100), pipelle biopsy was performed as office biopsy and 2th group (n = 100), dilatation curettage (D&C) was performed in operation room. Sampling was done by the same surgeon and was interpreted by the same pathologist.
    Results
    The samples were adequate in 1th group (n = 88), 88% and in 2th group (n = 98) 98%. Fisher test was used for statistical analysis. It reported statistical significant difference between pipelle biopsy and dilatation curettage (D&C) in terms of histopathology and samples efficacy (P = 0.01).
    Conclusions
    Obtained results demonstrated that efficacy of pipelle biopsy is high. Totally this procedure is safe and cost-effective with low complications. However, we should be careful to alternate pipelle biopsy instead of dilatation-curettage (D&C) in AUB approach.
    Keywords: Keywords: Abnormal Uterine Bleeding, Pipelle Biopsy, Dilatation, Curettage
  • Khadije Meghrazi *, Mojtaba Soleymani Sabet, Fateme Kheradmand, Masoomeh Akhgar Page 2
    Background
    The measurement of trace elements in human body has proved to be of great use in the evaluation of human health and the diagnosis of various diseases. No light, however, has been shed on these elements where they concern the human intelligence.
    Objectives
    The goal is to make a comparison between the students with a lower IQ and those having an ordinary IQ in terms of the amount of zinc and copper as two trace elements.
    Methods
    This is a case-control study and the subjects as the patients were chosen from mentally retarded students having no particular diseases. The sample size for the patient and control was 30 for each. The hair samples of the experimental group and the ordinary students (the control group) were digested with concentrated HNO3 after being washed with water and acetone. After being digested, the values of zinc and copper in the samples were measured with atomic absorption spectroscopy. The obtained data were analyzed using SPSS-15 via two independent sample tests of significance tests.
    Results
    The levels of zinc in the hair of students with lower IQ was shown to be 141.70 ± 88.56 µg/g and 198 ± 90.90 µg/g for that of the ordinary students (P = 0.01). The copper level for the samples of the experimental group was 11.90 ± 3.97 µg/g and 13.23 ± 3.97 µg/g in that of the control group, indicating no significant difference (P = 0.18) between the two groups.
    Conclusions
    The findings suggest that improving nutrition with zinc supplements may help enhance the development of learning and education in the students with lower IQ.
    Keywords: Trace Element, Hair, Lower IQ, Copper, Zinc
  • Masumeh Babayi, Mohammed N. Ashtiani * Page 3
    Background
    Consumption of hot substances may harm the surrounding bone around a dental implant. High temperatures at the bone-implant interface (BII) interferes with local cellular activities involved in the osteointegration.
    Objectives
    The present study was aimed at calculating the temperature distribution through the BII and the jaw bone under application of a transient cyclic thermal load.
    Methods
    In this numerical simulation, finite element method was employed in a commercialized dental implant model drawn by computer-aided design tools based on CT data to find the temperature in superficial and deep bone regions near the BII. The heat load was applied cyclically during the intake time.
    Results
    Results showed that the highest temperature was occurred at the top regions of the interface by magnitude of 48 C. Removal of the thermal loads also was followed by rapid decrease in the bone temperature.
    Conclusions
    Routine beverages of a hot liquid can increase the temperature of the bone beyond the biological thresholds of the bone cells vitality or remodeling functionality, specifically in the delayed loading types of implantation.
    Keywords: Dental Implant, Thermal Analysis, Finite Element, Bone Remodeling
  • Alireza Amirzadegan, Kaveh Hosseini, Ehsan Sekhavati Moghaddam, Younes Nozari, Masih Tajdini * Page 4
    Background
    Cardiovascular disease is a worldwide great burden on the health care syste early diagnosis and treatment of CAD can reduce the mortality and morbidity. We aimed to determine the association between upright T wave in lead V1 and coronary artery disease (CAD) in patients who presented with chest pain or positive non-invasive tests in emergency department.
    Methods
    In this retrospective cross sectional design we reviewed the clinical and coronary angiography data of patients who had normal ECG. Presence of coronary artery disease was compared between patients with and without upright T waves in V1.
    Results
    Data of 100 patients with upright T wave more than 1.5 mm in V1 was compared with 100 patients with completely normal ECG. Male patients with coronary artery disease (CAD) were dominant in upright T wave group. However, other traditional cardiovascular risk factors were not statistically different between groups. Based on the multivariate logistic regression model and after adjustment for confounding factors (i.e. gender, dyslipidemia and smoking), presence of upright T wave in the V1 and male gender were still associated with greater risk of coronary artery disease, Odds ratio 4.6 CI 95% (3.1 - 6.3) and 3.4 CI 95% (2.2 - 4.8), respectively.
    Conclusions
    In patients with chest pain and unremarkable ECG, presence of upright T wave in lead V1, is an early diagnostic tool for CAD. Male patients with chest pain and upright T wave in lead V1 probably have significant CAD.
    Keywords: Electrocardiography, Coronary Artery Disease, Coronary Angiography
  • Korosh Khanaki, Mahmood Abedinzade *, Moslem Mohammadi Page 5
    Background
    Diabetes mellitus is defined by hyperglycemia. Antidiabetic effects of Urtica dioica have been shown. Lamium album or nonstinging nettle is known to have useful impacts such as antioxidant and cytoprotective properties.
    Objectives
    The aim of the present study was to evaluate the serum concentration of insulin-like growth factor 1 (IGF-1) in diabetic rats given U. dioica and L. album extracts to distinguish any relationship between IGF-1 level and these plant extracts administration.
    Methods
    In this experimental study, 32 male rats divided into four groups; normal, diabetic, diabetic treated with U. dioica (100 mg/kg/daily), diabetic treated with L. album (100 mg/kg/daily) for 28 days. Fasting blood sugar (FBS) and IGF-1 concentrations were measured. One way ANOVA followed by the Tukey post hoc test was used for comparison between groups. In each group, FBS level among different times was compared using repeated measure ANOVA. Analysis was done using SPSS software version 22.
    Results
    FBS level significantly increased in diabetic rats compared with control rats (P
    Conclusions
    L. album and U. dioica might increase the level of serum IGF-1 in diabetes; with regard to insulin like activity of IGF-1, this might be viewed as a further support of positive influence of these plant extracts on this disease.
    Keywords: Diabetes, Lamium album, Insulin, Like Growth Factor 1, Urtica dioica