فهرست مطالب

International journal of basic science in medicine
Volume:2 Issue: 4, Dec 2017

  • تاریخ انتشار: 1396/10/30
  • تعداد عناوین: 8
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  • Mohammed Al-Thani, Al-Anoud Al-Thani, Walaa Al-Chetachi, Hammad Akram * Pages 161-165
    Overweight and obesity is a major public health issue worldwide impacting millions. The prevalence of increased body weight among children and adolescents is becoming a global phenomenon. The similar trend has been observed among residents of countries in the Persian Gulf region. The State of Qatar is also experiencing effects of obesity pandemic among adults and younger population. In order to examine obesity and overweight parameters, a literature review was carried out by using key scientific database systems. The results showed that the obesity is indeed a major public health issue among youth in Qatar. Furthermore, this mini-review examines the selected factors that could be associated with obesity and overweight situation among children and adolescents living in Qatar.
    Keywords: Qatar, Obesity, Overweight, Children, Adolescents, Epidemiology
  • Mehrdad Khatami, Mohammad Reza Aflatoonian*, Hakim. Azizi*, Ahmad Hooshmand, Farzad Augustino Minab, Mansour Khatami Pages 166-169
    Background
    Due to the useful applications of metal oxide nanoparticles in medicine, in this study iron oxide nanoparticles were biosynthesized using bioresource to evaluate its antibacterial activity against Escherichia coli.
    Methods
    The iron oxide nanoparticles were synthesized using bioresource as previously described. Macrodilution method of calculating the lowest concentration prevent the growth of bacteria (MIC); also, the lowest concentration that destroyed all bacterial cells were calculated (MBC).
    Results
    The lowest concentration of iron oxide nanoparticles that inhibited the growth of E. coli considered as a minimum inhibitory concentration (MIC) was recorded at the concentration of 250 µg/ml, but the minimum bactericidal concentration (MBC) of iron oxide nanoparticles was calculated at the concentration of 500 µg/ml.
    Conclusions
    The iron oxide nanoparticles were synthesized by green and eco-friendly, simple and inexpensive method. The biogenic iron oxide nanoparticles have impressive antibacterial properties. The results showed the inhibitory effect of the iron oxide nanoparticles of E. coli at 250 µg/ml. The iron oxide nanoparticles are effective antibacterial agents.
    Keywords: MICs, iron oxide nanoparticles, Antibacterial
  • Saeid Tanoorsaz, Naser Behpoor*, Vahid Tadibi Pages 172-177
    Introduction and aim: Cardiac apoptosis is one of the most important cardiovascular effects of diabetes. The aim of this study was to investigate changes in cardiac levels of caspase-8, Bcl-2and cardiac wall stress after 4 weeks of aerobic exercise in male rats with diabetes.
    Methodology
    40 adult male rats were randomly assigned to healthy control, Diabetes, healthy exercise and exercise瘦魺힬. Diabetic was induced by intraperitoneal injection of Streptozotocin solution (55 mg / kg). Two weeks after injection, fasting blood glucose levels were measured. After determining the induction of diabetes, the exercise program was performed for 4 weeks (5 sessions per week) at a speed of 18-15 m/min and 25-44 min. 48 hours after the last training session, the subjects were anesthetized and the heart muscle was removed. Caspase-8, Bcl-2 and NT-proBNP levels were measured by ELISA method.
    Results
    The induction of diabetes in the control group resulted in a significant increase in Caspase-8, NT-proBNP levels and insignificant Bcl-2 levels (p
    Conclusion
    The results of this study showed that diabetes increases the pre-apoptotic and cardiac cell wall stress levels and reduces the anti-apoptosis agent and possibly 4-weeks regular aerobic exercises can be used as a non-pharmacological strategy to reduce the complications of apoptosis in diabetes mellitus Cardiomyocytes.
    Keywords: Apoptosis, NT, proBNP, Streptozotocin, Wistar rats
  • Faegheh Golalizadeh Bibalan, Fatemeh Shobeiri *, Akram Ranjbar, Pooran Hagian Pages 178-183
    Background
    One of the health system concerns is connected with the use of labor pain relief medication and its side effects. Therefore, the aim of this study was to investigate the effect of labor pain relief by using the epidural spinal anesthesia (combined anesthesia) on labor outcome and satisfaction of pregnant women.
    Methods
    In this Randomized Controlled Trial study, included 80 nulliparous women who had been admitted in Fatemieh Hospital due to spontaneous onset of labor (2015-2016), and randomly assigned into two groups of 40 people in combined analgia (CA) group and normal vaginal delivery (NVD) group. Data collected by using of Demographic questionnaire, satisfaction questionnaire, baby truck scales. Data analyzed by descriptive and analytical statistic in SPSS version 16.
    Results
    Average maternal age (mean ± SD) in the intervention group was 34.4 ± 94.26 and in the control group was 18.5 ± 89.25, respectively. There was a significant difference between the two groups in terms of length of second stage of labor (P=0.001) , headache (P=0/04), Apgar score (1th minute) (P=0.001). Chi-square test show a significant difference between the two groups in terms of satisfaction with the childbirth (P=0.004)
    Conclusion
    In this study, labor pain relief by using the spinal - epidural anesthesia (combined) increased the satisfaction with the delivery method and was associated with some maternal and neonatal complications such as: headaches, length of third stage of labor, low Apgar score. It seems that the use of this method for painless delivery requires further studies.
    Keywords: Labor Pain, Patient satisfaction, Analgesia, Labor, Epidural spinal
  • Fatemeh Yousefnasab, Mohammad Reza Hajinezhad *, Hadi Hashemi, Abdolhossein Miri Pages 184-188
    Fenugreek (Trigonella foenum-graecum L) and Cordia myxa are widely used as antidiabetic herbal drugs in Iranian Traditional Medicine. We compared the effects of Trigonella foenum graecum seed aqueous extract (TE) with Cordia myxa fruit aqueous extract (CE) on diabetes-induced cognitive dysfunction through the use of passive avoidance learning (PAL) and memory task. We also determined the level of brain lipid peroxidation as a possible mechanism. In this experimental study, rats were randomly allocated into four groups (n=12/group) as the following: Group 1: Healthy control rats; Group 2: Diabetic control rats; Group 3: diabetic rats that received TE (870 mg/kg BW) for 30 days; Group 4: diabetic rats that received CE (500 mg/kg BW) for 30 days. Diabetes was induced by alloxan (120 mg/kg BW ip).
    Result
    Diabetes caused cognition deficits in passive avoidance learning and memory task. Cordia myxa fruit extract and Trigonella foenum graecum seeds extract significantly reduced serum blood glucose (P
    Conclusion
    Aqueous extract of fenugreek seeds is more effective in preventing diabetes-induced lipid peroxidation and memory loss compared to aqueous extract of Cordia myxa fruit. :
    Keywords: Trigonella foenum, graecum, Cordia myxa, Diabetes
  • Reza Shirazinia *, Dariush Saadati, Elyas Zeinali, Abolfazl Panahi Mishkar Pages 189-193
    Introduction
    Tuberculosis (TB) is a chronic disease. that spreads throughout respiration, food and direct contact and it makes lesions in lung or other organs. The most usual kind of tuberculosis is pulmonary TB. The high incidence rate of tuberculosis in east neighbor countries surrounding sistan has increased the prevalence of this disease in the Sistan region, the recent research was conducted to determine of incidence and epidemiology of TB in sistan region.
    Methods
    In this survey, data of all suspected and certain tuberculosis patients in Zabol city during 2010-2013 were collected from their profiles in the health care centers with contribution of TB center of Zabol. The prevalence of disease between urban and rural areas and between men and women was compared using Chi-square test. Trend of the disease was identified during these years using the regression line.
    Results
    In this period of time 458 cases (27%) were from urban areas and 1315 cases (73%) were from rural areas. The statistical analysis showed that incidence rate in rural areas is significantly more than urban areas (p
    Conclusion
    Dust storms in this area because of successive droughts and other living condition can make the circumstances suitable for spreading tuberculosis. So, people in the sistan region, especially in rural areas, should be given sufficient education to prevent tuberculosis. Keywords: Epidemiology, Sistan, Tuberculosis, Rural area
    Keywords: Epidemiology, Sistan, Tuberculosis, Rural area
  • Zohreh Afsharmand, Mojtaba Eizadi *, Maryam Farbod, Nader Shakeri Pages 194-199
    Introduction
    Obesity is closely associated with the development of systemic inflammation and cardiovascular disorders. The aim of our work was to evaluate the effects of aerobic training in absence to control diet on serum interleukin-6 (IL-6) and cardiovascular risk factors in obese women.
    Methods
    Physically inactive, non-trained obese women matched for age (38 ± 5 years of old) and BMI (30 ≤ BMI ≤ 36 kg/m2) that voluntarily participated in the study were randomly divided into exercise (moderate aerobic training, 6 weeks, 3 days/weekly, n=13) and control (no training, n = 13) groups. Pre and post training of anthropometrical markers, fasting serum IL-6 and cardiovascular risk factors were measured in 2 groups. Comparisons within groups were performed by paired Student’s t test and between groups by Student’s independent t test.
    Results
    Exercise group obtained significant decreases in body mass, BMI, body fat % and abdominal obesity as anthropometrical markers (p 0.05). However, aerobic training resulted in significant increase in low density lipoprotein-cholesterol (HDL) and decrease in TG/HDL and LDL/HDL (p
    Conclusion
    Despite a pharmacological property on cardiovascular system, short-time aerobic training does not appear to have an influence on circulating serum IL-6 as inflammatory cytokine in obese females.
    Keywords: Aerobic training, cardiovascular risk factor, Inflammation, Obesity