مجله دانشکده پزشکی اصفهان
پیاپی 487 (هفته سوم شهریور ماه 1397)

Epilepsy is one of the most common diseases of central nervous system (CNS). In Iran, about1,200,000 people suffering from this disease are living; many of them are drug-resistant to whom neurosurgeryfor removing the epileptic zone is suggested. For doing so, a series of preoperative assessments should be doneto identify the epileptic zone. Since for each such patient, a wide variety of data are gathered, it is necessary tostore and compile the data.
In 2005, the Isfahan Comprehensive Epilepsy Center (ICEC) was formed as the first in Iran. Since
then, until 2015, about 1673 patients with drug-resistant epilepsy were admitted in this center.
Findings: For these patients, brain magnetic resonance imaging (MRI) and 24-hour electroencephalography(EEG) monitoring were done. 709 patients were referred for further neuropsychiatric assessments. Epilepsymeeting was made to analyze and decide the method of treatment for these patients, and the data gathered during
these processes were reviewed. About 330 patients were treated surgically, and others left the process. The most
visible outcome of this program was the fact that all the data of all the patients were kept and gathered, 500 items
for each patient.
This data center is of the most comprehensive data centers in Iran. This data center received a greatattention in Iran, and is confirmed by Iranian Ministry of Health and Medical Education as a referral center. Itcan be an infrastructure for a mega-datacenter in future in Iran to be used to study the pattern of brain andbehavior relations.

Mental health is one of the most significant aspects of health in adolescence, to which, if we do
not pay attention, may lead to complications in teenager's life. Therefore, it is necessary to find a way to increase
mental health in this period. This study aimed to compare the effect of mental health education by two methods,
role playing and small group discussion, on boy teenagers’ mental health.
This was a study on 183 boy students selected randomly from 4 random schools in one of areas of
education and training in Isfahan City, Iran (92 boys in small groups of discussion and 91 in play a role group).
Evaluation of the intervention was carried out prior to Goldberg questionnaire, two months after the intervention.
Findings: The education led to a significant decrease in the overall mental health score in both the methods, but
in the role playing group, the effect was more (11.57 ± 8.74) than small groups of discussion (14.58 ± 10.52)
(P 0.001) and physical symptoms (3.13 ± 2.32 vs. 4.01 ± 3.26, P = 0.011) were significantly
less in role playing group, too.
Regarding the effect of role playing method in improving public health, it can be used effectively to
promote boy students’ mental health.

Cognitive impairment is one of the most common, severe, and life-threatening complications aftersurgery that understanding the factors affecting it, reduces the incidence of this complication. Therefore, the aimof this study was to investigate the prevalence of cognitive impairment after anesthesia in patients over 60 yearsof age, and determination of risk factors.
The study included 384 patients older than 60 years of age undergoing surgery. Mini mental state
examination (MMSE) questionnaire was used to assess demographic and cognitive impairment before, and one and three days after the surgery. To compare quantities and qualitative data, t, chi-square, and Mann-Whitneytests were recruited.
Findings: The frequency of mild and moderate cognitive impairment was 21.6 and 1.8, 38.8 and 12.5, and 46.6a nd 5.2 percent before, and one and three days after the surgery, respectively. The high prevalence of cognitive
impairment after surgery had significant correlation with older age, female gender, low education levels, being
single, smoking and alcohol consumption, general anesthesia, and longer hospitalization (P Based on these findings, we can say that the prevalence of cognitive impairment in the elderly was
high after surgery. Moreover, we found that older age, female gender, low education, single people, history ofsmoking and alcohol consumption, general anesthesia, and length of stay in hospital increased cognitiveimpairment in patients over age 60 years of age.

Restless legs syndrome (RLS) is a sensory-motor disorder in which, a person experiences leg
discomfort, and tries to improve it by leg motion. Pregnancy is among the factors that primarily causes or
secondarily exacerbates restless legs syndrome. In this study, we assessed the incidence of this syndrome among
pregnant women, and its association with preterm delivery.
This was a cross-sectional study on 172 pregnant women with preeclampsia in 2015-2018 selected
based on a census method. Restless legs syndrome diagnostic questionnaire and its severity based on
International Restless Leg Syndrome Study Group rating scale (IRLS) were evaluated and compared in patients.
Moreover, demographic information including age, smoking, body mass index (BMI), number of gravities,
number of abortions, age of pregnancy, type of delivery, neonate's weight at the time of delivery, and neonates'
gender were recorded and compared.
Findings: There was no association between restless legs syndrome and mother's age, body mass index,
smoking, number of gravities, number of abortions, and time of delivery (P > 0.050 for all). Duration of
pregnancy was 33.43 ± 3.87 and 32.22 ± 4.26 weeks in patients with and without restless legs syndrome,
respectively. 85.7% of patients with restless legs syndrome had preterm delivery. Severity of restless legs
syndrome was 17.47 ± 6.11 and 12.5 ± 3.98 in patients with preterm and term labor, respectively, but no
significant association (P = 0.063).
Based on findings of the current study, although restless legs syndrome among the women with
preeclampsia was accompanied with preterm labor, and also was more severe among them, no statisticalassociation was found in these regards. Further studies are recommended.