فهرست مطالب

  • Volume:6 Issue:3, 2018
  • تاریخ انتشار: 1397/04/12
  • تعداد عناوین: 3
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  • Satiya Jinendra Bhuiyan Nadir Kalidindi Venkat Pages 29-31
    Acute promyelocytic leukemia represents a medical emergency with a high rate of early mortality. It has a high predilection for disseminated intravascular coagulation and in the absence of treatment, can be rapidly fatal. Without treatment, the median survival is less than 1 month.The coagulopathy in APL is complex and can be attributed to a combination of thrombocytopenia, disseminated intravascular coagulation and hyperfibrinolysis. White blood cell count at presentation is an important predictor of early hemorrhagic death. With the discovery of all-trans retinoic acid and arsenic trioxide, acute promyelocytic leukemia has transformed from a devastating disease into one of the most curable malignancies.Patients should be monitored for the development of differentiation syndrome, seen in 25 % of patients within 2-21 days of initiation of treatment. Early death is still a key issue, particularly in the elderly population, reiterating the importance of rapid diagnosis and treatment.We report the case of a 48 year-old-male diagnosed with the microgranular variant of acute promyelocytic leukemia M3 subtype and treated with all-trans retinoic acid and arsenic trioxide who achieved complete hematological remission.
    Keywords: acute promyelocytic leukemia, microgranular variant, fluorescence in situ hybridization, all-trans retinoic acid, arsenic trioxide
  • de Assis Pereira Hansen Cristiano Pages 32-35
    Chronic urticaria is a commom health problem. Though not a rare disease, only part of these patients are correctly diagnosed and even fewer of them evaluated and treated in a proper way. Herein described, a case report of an old female with such diagnosis since 8 years ago. She suffered from multiple episodes of diffuse and itching hives and plaques evaluated by dermatologists and allergy specialists along these past years. Skin lesions of long lasting nature and pettechial appearance made this diagnosis reappraised and a skin biopsy was ordered. Vasculitis was shown. The bottom line: leukocytoclastic vasculitis mistaken for chronic urticaria is something to be considered when evaluating an apparent simple case of chronic idiopathic urticaria.
    Keywords: urticaria, cutaneous leukocytoclastic vasculitis, differential diagnosis
  • Kangsaputra Ferdy Bangun Praba Barry Arief Windya Pages 36-38
    The management of high-grade renal trauma remains debatable in various education centers, especially the cases of patients with stable hemodynamics This paper reports the case of a 24 year old man with grade IV renal trauma due to blunt injury in the left waist. The patient had stable hemodynamics, and was given a conservative management followed by 3 months of post trauma treatment. In this case, the conservative management has resulted in a satisfactory outcome, confirming that conservative management is an appropriate alternative treatment for patients with similar cases. This paper also shows the radiology test and the implementation of the conservative approach in the treatment of life-threatening renal trauma.
    Keywords: high-grade renal trauma, conservative management, isolated renal trauma