مجله علوم پزشکی پارس
سال شانزدهم شماره 3 (پیاپی 45، پاییز 1397)

Metered Dose Inhalers (MDIs) are the most common drugs for the control of asthma. This study was conducted to evaluate usage patterns, satisfaction with and concerns about MDIs for children with asthma and the related factors from the viewpoints’ of their parents. This cross-sectional study was conducted on children with asthma who referred to asthma and allergy clinics in two teaching hospitals of Kerman University of Medical Sciences in Iran. The mean and SD of age of the patients were 7.58±4.01 years. More than 95% of the patients were taking anti-asthmatic drugs at the time of the study. Of the patients who used anti-asthmatic drugs, 86.6% were using MDIs alone or in combination with oral anti-asthmatic drugs. Of patients who took MDIs, 73.7% were using a combination of bronchodilator and corticosteroid, 22% bronchodilator alone, and 2.3% corticosteroids alone. More than 91% of the parents were satisfied and 95.9 % of them were concerned about the usage of MDIs. Dependence to MDIs (90.1%) and high costs of MDIs (81.3%) were the most frequent causes of concern about MDIs usage. Despite high satisfaction of parents with MDIs for control of asthma in children, concerns of parents about MDIs usage can cause the deprivation of children from these highly effective drugs. Proper education can correct attitudes of patients or parents and decrease their concerns about MDIs usage.

Diabetic foot ulcers, which are complications of diabetes mellitus, can be accompanied by an infection in the wound, which can increase the risk of amputation or even death. E coli bacteria, which have been reported to be present in diabetic foot ulcers, can lead to worsening of the condition of the wound. The aim of this study was to detect β-lactamase genes in Escherichia coli isolated from diabetic foot ulcer by Multiplex PCR in Jahrom city. Determination of antibacterial sensitivity of Escherichia coli isolated using disc diffusion method. The detection of strains producing ESBL enzymes was performed using Double disk synergy test. In order to detect carbapenem resistant organisms in the TSF, the concentration of 0.5 McFarland was used. To isolate and identify MBL-producing strains, the Etest MBL (AB BioDisk, Solna, Sweden) tapes was used according to the manufacturer's instructions. In a multiplex PCR assay, using specific primers, the presence of genes encoding beta-lactamase enzymes including blaTEM, blaSHV and blaOXA-1 was studied.

Introduction and Aims: Type, intensity and duration of exercise, determining the effect of exercise on haematological indexes. The aim of this study was comparison of the effects of acute moderate-and high-intensity aerobic exercise on some hematological parameters and exercise-induced thrombocytosis in female college futsal players. Eleven female futsal player of Jahrom University who had at least six months futsal training, voluntarily participated in this study. Subjects, runs on the track and field piste for 30 min at 65 % maximal heart rate in first week and in second week run with 80% maximal Heart rate. Blood was drawn immediately before and after exercise. The results showed that blood platelets (P=0.02), hematocrit (P=0.001), the mean corpuscular volume (P=0.01) was significantly increased after moderate-intensity exercise. Also, blood platelets (P=0.001), the mean corpuscular volume (P=0.01) increased significantly and hemoglobins (P=0.001), and the mean corpuscular hemoglobin concentration values (P=0.001), was significantly reduced after high intensity exercise. There was significant difference in hemoglobins (P=0.007), mean corpuscular hemoglobin (P=0.004) and the mean corpuscular hemoglobin concentration (P=0.002) values between moderate-and high-intensity exercise. Based on the findings of this study, acute exercise with different intensity can have a significant effect on some blood parameters in female futsal academic.

Health promotion behaviors are one of the key determinants of health. By determining the type locus of control of people, the sense of efficiency increases in individuals. The aim of this study was to compare health promotion behaviors and health locus of control in two groups of medical and non-medical students. Material and method: This cross-sectional study was carried out on 500 medical students and non-medical students with quota-based sampling. The data collection tool was a Demographic Information, Health Promotion Lifestyle Profile II and Walton Questionnaire.
Statistical analysis was performed by using Chi-square, independent t-test and Multiple linear regression in SPSS software version 18 at a significant level of 0.05. Results showed a significant difference in health responsibility P<0.001, physical activity P=0.007, nutrition P<0.001, spiritual growth P<0.001, interpersonal relations P=0.01, and stress management P<0.001 structures and also a significant difference in internal health locus of control P=0.03 and the external health locus of control P<0.001 in medical and non-medical students. The results show that health promotion behaviors in medical students are in a better position than non-medical students. In the future, studies are needed to consider the various factors that can be effective in determining the health locus of control.

Deleterious effects of lipid accumulation in non-adipose tissues are known as lipotoxicity. The prevalence of cardiovascular disease due to lipotoxicity has been dramatically increased worldwide. Based on available reports, palmitic acid induced lipotoxicity in several cell type like cardiomyocyte and hepatocytes while oleic acid could prevent the lipotoxicity in rat hepatocytes because Unsaturated fatty acids may counteract the lipotoxicity associated with saturated fatty acids. This study aimed to investigate the effects of combination of linoleic acid with linoleic acid on the induced lipotoxicity by palmitic acid in adult rat cardiomyocyte. Ventricular heart muscle cells were isolated and seeded into 24-well-plates. Cells were treated with palmitic (0.5 mM), linoleic acid (0.25 mM)+linolenic acid (0.5 mM), palmitic+ linoleic acid+linolenic acid (0.5 mM+0.25 mM+0.5 mM) or left as control. Triacylglycerol (TAG), diacylglycerol (DAG), DNA fragmentation and percent of viability were measured at 24, 48 hours. Findings: Result showed that linoleic acid+linolenic acid decreased DAG and DNA fragmentation and increased TAG and cell viability when co-administrated with palmitic in comparison with palmitic alone (p<0.05). In conclusion, combonation of linoleic+linolenic acid would improve the lipotoxicity indices of palmitic acid in primary adult rat cardiomyocytes culture.

The Accident is an event that causes damage to be detected. Increasing in traffic accidents threaten the community health promotion. Physical, financial and psychological disadvantages of accident are essential to invest a public health priority. This study evaluated the epidemiology of accidents and injuries of motorcycles and bicycles riders in Jahrom city. In this cross-sectional study, 14111 accidents accidents motorcycles and bicycles Jahrom emergency census registration statistics were extracted from 89-93 years. The data gathered by a check lists of 115 emergency care. Data were analyzed with descriptive statistics and logistic regression by software version 14. 62.7 % were facing urban accidents. 57.9 % and 61.4 % of injury of accidents on the day in children under 30 years old. 1.3% of fatal accident and others were injury. Most accidents occurred in the 12 to 2pm and 18 to 20pm. Most prevalent trauma, a blow to the organs (41.2%) and head trauma (28.9 %). Car-motorcycles (50.3%) and motor reversal (32.9%) were the most vehicle accidents involved. Occupants died at the crash area (OR= 2.77), season (OR= 1.15), age (OR= 0.624) and sex (OR= 2.065) were associated. Fatal accident motorcycle riders, are mostly outside the city and daylight, those occurred in early age and men and most commonly injuries are a blow to the organs and head trauma. Therefore, educational planning necessary to inform people about accident risks and use of helmets. On the other hand, emergency activities focus in suburban accidents and timely on scene presence.

Adolescence is a critical period of life characterized by changes and rapid growth, Behavioral changes in this period are effective on person's health. The aim of study was to estimate the prevalence of health risk behaviors among high school students of Qom. This research is descriptive-cross sectional. the sample consisted of 800 high school students in Qom (400 girls and 400 boys) that were selected by randomly multistage sampling.The research instrument was a demographic questionnaire and a standard questionnaire. Data were analyzed using descriptive statistics by SPSS24 software. Findings showed that use of hookah was the most popular in girls and boys (59%) as compared with cigarette smoking (54.13%), drug use (33%), and alcohol consumption (44.25%). The prevalence of physical violence in and outside the school in one year, carrying weapons to school in a month, cigarette smoking in the school in one month, smoking hookah, and alcohol and opioid use during one month were more frequently observed in boys than girls. The use of the seat belt was more common among girls than boys, and the total prevalence of using the seat belt was very low( 4.1 %). Due to high incidence of High Risk Behaviors in high school students, there is a need for strategic plans and scientific interventions in this age group Which are the future makers of country.