مجله دانشگاه علوم پزشکی سبزوار
سال بیست و ششم شماره 5 (پیاپی 106، آذر و دی 1398)

Firefighting is due to high physical demand and activities such as running, rising, and responding quickly to a variety of different situations, endure high mental workload And these sudden make changes in work situations will put a lot of psychological stress on the firefighters. The purpose of this study was investigating the level of mental health in firefighters.

This cross-sectional study was conducted on 65 randomly selected firefighters in Khorasan Razavi Province. The data were collected using the NASA Task Load Index (NASA-TLX), stress and quality of life questionnaire. Data analysis was performed in SPSS, version 20, using descriptive statistics, Pearson correlation coefficient, ANOVA, and independent samples t-test.

The results of stress, NASA-TLX and quality work life demonstrated that the mean scores of were 169.2, 66.4 and 84.3 respectively, stress and mental workload were at a high level and quality of work life was low. A significant relationship was found between stress, mental workload and quality of work life(p

Considering the adverse effects of synthetic antioxidants, anticancer drugs and antibiotics on human health, in this study, bioactivities of Mentha longifolia essential oils collected from Marivan and Qaza An were examined and compared with each other for identification a natural alternative of synthetic antioxidants, anticancer drugs and antibiotics.

Essential oil of M. longifolia leaves and stems collected from Marivan and Qaza An was prepared using solvent-free microwave extraction method. The essential oil components were identified by gas chromatography/mass spectrometry. The antioxidant and cytotoxicity activity of the essential oils were determined via β–carotene bleaching assay and brine shrimp lethality test, respectively. The antimicrobial activity of the essential oils was evaluated by the agar well diffusion method and by determination of minimum inhibitory concentration.

The main components of M. longifolia essential oil collected from Marivan were pulegone (81.45%) and isopulegol (8.39%) and the main components of M. longifolia essential oil collected from Qaza An were pulegone (48.29%) and piperitenone oxide (23.53%). The inhibition of linoleic acid oxidation by M. longifolia essential oils collected from Marivan, Qaza An and BHT were 80.02%, 78.59% and 95.50%, respectively. The LC50 of the M. longifolia essential oils collected from Marivan, Qaza An and vincristine sulfate were 53.47μg/ml, 55.96 μg/ml and 0.751 μg/ml, respectively. M. longifolia essential oils had good antimicrobial activity, especially against gram-positive bacteria.

M. longifolia essential oils have significant antioxidant, antimicrobial and anticancer activity and can be introduced as alternatives of synthetic antioxidants, antibiotics and anti-cancer drugs.

This study was implemented in order to study the role of neurosis and mindfulness in predicting the quality of life of diabetic patients in Delfan.

The research is a descriptive-correlational study. The study population included all diabetic patients, 945 individuals, in Delfan in second half of year 2015. Accordingly, using Cochran formula, 197 people were selected using simple cluster random sampling. To measure the variables of research, the mindfulness questionnaire (Bauer and colleague, 2006), quality of life questionnaire (WHO, 1996), and NEO questionnaire of neurosis (Casta and Maccarry, 1992) were used. Data were analyzed using Pearson correlation and stepwise multiple regressions.

The results showed that there is a significant positive relationship between mindfulness with quality of life. Also, there is a significant negative relationship between neuroticism with quality of life. Regarding the amount of beta of non-judgment (Beta= 0.249), neuroticism with beta coefficient (Beta = 0.588), conscious action with beta coefficient (Beta = 0.286) and observation with beta coefficient (Beta = 0.151) are the most powerful variables to predict the quality of life of diabetic patients.

According to research findings, it seems that improving the mindfulness in diabetic patients, will increase the quality of life and decrease the neurosis.

In this study, the synthesis of nanoparticles of manganese-zinc oxide and zinc iron oxide by chemical co- precipitation method performed and investigation of structural and morphological properties of related nanoparticles using Fourier Infrared spectrum, X-ray diffraction and Transmission electron microscopy were carried out. Antimicrobial effects against shigella flexneri (PTCC 1234) determined by inhibitory diameter zone method. Synergistic effect of nanoparticle with hydrogen peroxide and hypochlorite sodium also assessed by calculation of the fractional inhibitory concentration (FIC) index. Structural analysis of Mn- ZnO and Fe- ZnO nanoparticle revealed that co- precipitation is a suitable method for synthesis of these nanoparticles. Results of antimicrobial tests showed that Mn- ZnO nanoparticles has more antibacterial effect against shigella flexneri than Fe- ZnO nanoparticles. Inhibitory zone diameter of Mn- ZnO and Fe- ZnO were 25 and 14 mm, respectively. In addition, both doped nanoparticle exhibited more antimicrobial effect than zinc oxide nanoparticle so, doping cause increasing antimicrobial effect of zinc oxide nanoparticle. Furthermore, combination of nanoparticles with hydrogen peroxide and hypochlorite sodium showed synergistic effects which was complete synergistic at high concentration and partial synergistic at low concentrations.

An empty nest syndrome is a kind of mental wilting, which is felt in the parents after the emptying of the house from their children and their absence along with parents, since the occurrence of this syndrome in middle age and ages Higher socially in this age group can have a special effect on the overall health of the community. Therefore, the present study aimed to determine the efficacy of a group therapy based on acceptance and commitment on the quality of life of the elderly with nasal syndrome.

A quasi-experimental research was carried out with a pretest-posttest design with control group. The statistical population consisted of all elderly people referred to the Mashhad Mashhad Psychiatric Center in 2018. In this voluntary and voluntary sample population, 30 elderly as a sample were randomly assigned to two groups of 15 experimental and control groups. The experimental group underwent eight sessions of 90 minutes of treatment based on acceptance and commitment, and the control group did not receive any treatment. Both groups responded to the quality of life questionnaire (IRQOL) at the beginning and the end of treatment. Statistical analysis of data was done with SPSS-22 software and inferential statistics (covariance analysis) (p

Evidence suggests that considering the type of heart disease diagnosis, people's quality of life can be different; Therefore, the aim of this study was to compare the quality of life in patients with acute myocardial infarction, heart failure and normal in 2014. Martials and

This descriptive study was which 100 patients with heart disease - cardiovascular (50 patients with acute myocardial infarction and 50 patients with heart failure) and 50 normal people who were matched in terms of demographic characteristics of patients In 2014 the sampling were selected. Information collected by (QOL) questionnaire at a significant level of 0.05 and univariate analysis of variance were analyzed using SPSS version 20.

According to the findings, among heart patients and normal subjects there is a significant difference between quality of life (P=0.001); so patients with acute myocardial infarction and heart failure have lower scores in terms of quality of life than normal people. Also, no significant differences was observed in quality of life with acute myocardial infarction and heart failure (P=0.670).

Due to differences in the quality of life for heart patients and normal people, education and awareness of heart disease in these categories seem to be necessary

Attention deficit / hyperactivity disorder is the most common childhood that can affect the child's social and educational life. Considering that different therapies have been used to relieve the symptoms of this disorder, the purpose of this study was to investigate the effectiveness of cognitive-educational teaching on verbal self-learning on social interactions, anxiety and autonomy of these children.

This is a semi-experimental research. The statistical population of this study was all children with attention deficit / hyperactivity disorder, of which 30 were selected from clients referring to Sabzevar Counseling and Psychology Clinic and completely Randomized in both experimental and control groups. Data were collected from the children's spence anxiety questionnaire, Social Interactions, Kearsam and Elliot (1990), and Michael King's Self-Defense Questionnaire and for attention deficit / hyperactivity disorder recognition. The Convergs Questionnaire (1960) was used for parents' form, for data analysis, statistics Descriptive, mean standard deviation and inferential statistics of multivariate covariance analysis were used and data were analyzed using spss22 software.

Findings showed that the effect of verbal self-learning on the social interactions of children with attention deficit / hyperactivity disorder was positive and significant (P

Quality of Working Life is a critical concept with great importance in the life of an employee which shows an appropriate balance between work and personal life, ensuring or organizational productivity and employee’s job satisfaction. The purpose of this study was to determine the effect of group training of assertiveness on improvement in the quality of work life of Khatam-ol-Anbia hospital staff.

The method of this study is terms of purpose was applied and in term of data collection method was pseudo experimental and designed was pretest-posttest with control group. The sample of the study included 30 employees who were voluntary selected and randomly divided into control and experimental groups (each of them 15 people) .assertiveness skills were applied as the independent variable on the experimental group. The data collection tool was the Walton Quality of Work Life questionnaire. The Data were analyzed with analysis of covariance.

The results suggested that there is a difference between experimental and control groups after performing the intervention. In other words, the use of group training assertiveness has enhanced quality of work life among the employees in the post-test (p< 0.05).

It seems quality of work life is an important issue in the Workplace. Organizations can use group training assertiveness and self-expression in order to improve the quality of work life and increase employees’ satisfaction.

Backgrand: The relationship between job satisfaction and organizational commitment is as most important factor in the management science. One of the basic factors influencing commitment is employee's job satisfaction. The purpose of study was investigate the relationship between job satisfaction with organizational commitment and its influential factors in staff working in Sabzevar University of Medical Sciences. This cross-sectional study was carried out on 288 employees from different fields. The instrument was a Demographic information, Job Satisfaction Questionnaire (JDI) and organizational commitment of Allen & Meyer. The collected data were analyzed by descriptive statistics, Spearman, Naparametric Test and with SPSS24. Results showed that job satisfaction and organizational commitment of employees in all dimensions were higher than the average level. The highest level of job satisfaction was observed in the dimension of the co-worker and the highest organizational commitment of the employees in emotional dimension. There was a positive and significant relationship between job satisfaction and organizational commitment of employees.(r=0.32-p

The genus Mycobacterium is a group of acid fast bacteria with DNA G+C content of 61-71% and the cell wall containing mycolic acid. According to growth physiology, mycobacteria grouped into two divisions: rapidly-growing and slow-growing mycobacteria. Three groups of mycobacteria exist based on pigment production: nonpigmented (nonphotochromogens), photo-chromogens and scotochromogen. Both human obligate pathogens (M. tuberculosis and M.leprae) and opportunistic species exist in mycobacteria genus. There is different kind of mycobacterial infections such asrespiratory infections, lymphatic node and skeletal involvement, dermal and disseminated infection. Spread of HIV virus and immunodeficiency in recent years makes the mycobacterial infections one of the most dangerous infections. Acid fast staining, biochemical tests and cell wall mycolic acid and fatty acid analysis are used for detection of mycobacteria. Different molecular tests including different PCR basedmethods; hybridization and sequencing tests are used for diagnosis and also verifying phenotypic and biochemical tests. Clarithromycin, rifabutin, ciprofloxacin, rifampin and ethambutol currently were used for treatment of slow growing mycobacterial infections. Whereas macrolides, cephalosporins and fluoroquinolones are used for rapidly growing treatment. For rapidly growing mycobacteria, disk diffusion method, disk elution method and broth micro dilution method are more appropriate. Radiometric methods and broth micro dilution method are choice methods for slow growing mycobacteria drug susceptibility test. Moreover molecular methods like PCR single-strand conformational polymorphism (PCR-SSCP), Sequencing, PCR-RFLP and Multiplex-PCR are developed for drug susceptibility determination in mycobacteria. According to non-tuberculosis mycobacteria clinical significance, clinical laboratories and health care team most take attention to diagnosis of these bacterial infections.

Vitamin D is a fat-soluble vitamin, which has been well known for its role on calcium and phosphate homeostasis since many years ago, but several studies in recent years have shown that vitamin D is involved in a variety of other processes which can be included its role on the immune system and the related diseases. In this article, the most recent findings about the role of vitamin D in the immune system and a number of immune-related diseases have been investigated. Reviewing the articles shows that vitamin D and its receptor have an important role in the function of the body immune system. It seems that screening of vitamin D levels in the society can play a useful role not only in the preventing certain diseases and cancers but also in reducing the severity of the disease and better responding to common treatments.

Collagen synthesis can help to heal wounds, especially Large wounds. Any treatments that can stimulate collagen synthesis in fibroblasts can accelerate wound repair, so it has clinical value. Stem cells secrete some macromolecules and signals that can have different effects in other cells.

In this study, human mesenchymal stem cells were cultured and their medium supernatant was harvested as a medium containing the signal. After determining concentration, they were exposed to mouse fibroblasts. The cell viability was examined and then in the molecular section, by designing specific primers, three The collagen gene was evaluated by Real-Time PCR.

The results indicated a growth-promoting effect using the amount of 20 μg /ml of stem cells conditioned media in the culture medium of fibroblast cells. It was also found in the molecular section, that this concentration could increase the expression of all three selected collagen genes.Discussion and

The results of this study fully confirmed the initial goals, indicating the high power of mesenchymal stem cells in the induction of collagen synthesis, and thus could be a very good candidate for clinical studies.