فهرست مطالب

Dermatology - Volume:22 Issue: 3, Autumn 2019

Iranian Journal Of Dermatology
Volume:22 Issue: 3, Autumn 2019

  • تاریخ انتشار: 1398/06/10
  • تعداد عناوین: 7
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  • Golnaz Mehran, Saba Sepasgozar, Masoomeh Rohaninasab, Azadeh Goodarzi, Mohammadreza Ghassemi, Mahrokh Fotooei, Elham Behrangi * Pages 87-91
    Background
    Microneedling has been shown to be a clinically effective and safe treatment for comedonal acne vulgaris. The aim of the present study was to compare the clinical effectof microneedling and the most commonly used topical drug, tretinoin, in the treatment of comedonal acne.
    Methods
    Patients with comedonal acne (n = 82) were randomized to receive topical tretinoin (n = 41) or 6 sessions of microneedling (n = 41) over a period of 3 months. Objective assessments suchas changes in acne severity score by global acne grading system (GAGS) and patients’ subjective satisfaction were investigated at the baseline, at the end of the treatment period, and at the3-month follow up.
    Results
    GAGS was significantly reduced in both microneedling (7.8±3.8 to 3.5±2.6) and tretinoin (8±3.8 to 6.6±3.2) groups at the end of the treatment course compared with the baseline. Theoverall acne severity index reduction in microneedling group was significantly higher than that of the tretinoin group (P<0.001). Improvement in acne severity was also more permanent bymicroneedling. The severity of acne in tretinoin recipients was increased to 8.2±3.2 at the follow-up visit, while it remained nearly unchanged in the microneedling group. (3.3±2.4). Patients’subjective assessment concerning acne improvement was significantly more satisfactory in microneedling group (P<0.001). 
    Conclusion
    Compared with tretinoin, microneedling seems to be a more effective, permanent and satisfactory treatment in the treatment of comedonal acne.
    Keywords: Acne, comedone, microneedling, Tretinoin
  • Robabeh Abedini, Vahideh Lajevardi, Maryam Nasimi *, Zahra Hallaji, Mahtab Darvish Pages 92-96
    Background
    The role of smoking and alcohol consumption in the pathogenesis of psoriasis is well-known; however, certain published studies have focused on the relationship between substance abuse and psoriasis. The present study was conducted to evaluate the prevalence of tobacco smoking, and substance and alcohol use in patients with psoriasis.
    Methods
    Patients with a definite diagnosis of psoriasis at ages of 15 or more were recruited and general information of patients and their smoking behavior, alcohol consumption and substanceabuse were further collected.
    Results
    203 patients (103 men and 100 women) with psoriasis were included in this cross-sectional study. There were 76 smokers (37.45%) and 49 patients (24.1%) who consumed alcohol. Smoking, opium and alcohol consumption were significantly higher in men with psoriasis compared with women (P-values = 0.0001, 0.003, 0.002, respectively). Tranquilizer use was higher in married patients (P = 0.002), and those with joint involvements (P = 0.009). Hookah use was considerably high in female psoriatic patients, although not statistically significant (P = 0.37). Moreover, patients older than 40 years, and with nail disease (odds Ratio = 3.8) weremore prone to hookah use. 
    Conclusion
    Our study revealed that the prevalence of smoking, opium and alcohol consumption is higher in men with psoriasis. Moreover, tranquilizer use is higher in married patients, and those with joint involvements. These findings should prompt public health workers to consider the modifiable habitual risk factors in patients with psoriasis.
    Keywords: Psoriasis, smoking, alcohol, hookah, Substance abuse
  • Azadeh Goodarzi * Pages 97-106
    There are many patients with inflammatory acne vulgaris who are not compliant or eligible to consume acne medications, such as oral antibiotics or isotretinoin. PubMed and Medline databases were searched for all related articles. All finding were summarized and chronologically presented in the tables. Nonmedical device-based therapies largely improve the treatment of active inflammatory acne vulgaris, especially in patients who are not compliant or eligible to consume acne medications, do not respond to these drugs over a specified period of time, or do not sustain in the remission phase.
    Keywords: Acne Vulgaris, Laser, radiofrequency, microneedling, photodynamic therapy (PDT)
  • Daniel Henry *, Adarshlata Singh, Bhushan Madke, Palak Kedia Pages 107-109
    Tinea corporis is a superficial dermatophyte infection. This is a case report of a 45-year-old female presenting with a history of erythematous raised lesions with itching all over the body since one year ago. Based on clinical findings, the lesions were diagnosed as tinea corporis. A KOH smear was carried out and results were negative probably due to application of steroids, and a histopathological examination was done. On histopathological examination, the patient was proved to have dermatophytosis caused by Trichophyton mentagrophytes. The patient was successfully treated with oral itraconazole 200mg once a day and griseofulvin 250 mg once a day along with 2 % ketoconazole for topical application.
    Keywords: Tinea corporis, itch, Dermatophyte
  • Armaghan Gharehaghaji Zare, Faranak Ghasemi *, Asal Sadri, Ghazal Sadri Pages 110-114
    Progeroid syndromes, one of which is metageria, are characterized by signs of premature aging with multiple systemic and skin symptoms. Here we describe an 8-year-old girl with no historyof specific underlying disease in her family, no hair growth at the scalp since she was born, and taller and thinner than her peers. We noticed diffuse subcutaneous fat atrophy. The patientwas referred to Sina Hospital, Tabriz because of the appearance of pseudomilia lesions throughout the body following pulse corticosteroid therapy. Proper and timely diagnosis of progeroid syndromes is important in preventing undesirable side effects. Introducing this case is important as it prevents other patients from undergoing corticosteroid therapy due to misdiagnoses, such as alopecia areata.
    Keywords: acrogeria, metageria, progeroid syndromes, Werner syndrome
  • Kang Nien How *, Ikmal Bakrin, Norashikin Shamsudin Pages 115-119
    Granuloma annulare (GA) is an idiopathic benign skin disease, characterized by annular dermal plaques or papules. Much is still unknown concerning its aetiology, association, and pathogenesis.We report two patients with generalized GA (GGA), with different age of presentation, co-morbidities, and disease morphology. Herein, we report two patients with GGA with different clinical features, disease morphologies, and histology patterns. We also illustrate the treatment used in our patients and the outcome. GA is a self-limiting disease and can regress spontaneously. GGA tends to be more persistent and usually requires treatment for symptomatic or cosmetic reasons. Expert consensus on treatments recommends topical corticosteroid, psoralen and ultraviolet A (PUVA), and antimalarial drugs.
    Keywords: generalized granuloma annulare, pallisade, interstitial, hydroxychloroquine, Diabetes Mellitus
  • Fahimeh Abdollahimajd *, Zeinab Bizaval, Mohammad Shahidi Dadras, Mohammad Nikvar Pages 120-122