مجله دانشکده پزشکی اصفهان
پیاپی 560 (هفته چهارم اسفند 1398)

Studies has shown that the time-of-day of exercise can have different effects on inflammatory parameters. The aim of the present study was to compare the acute responses of some of inflammatory indicators [C-reactive protein (CRP), tumor necrosis factor-α (TNF-α), and interleukin 6 (IL-6)] to acute bouts of circle resistance exercise at different times of the day (morning vs. evening) in obese men.

In the quasi-experimental study, 15 healthy obese men with mean age of 23.84 ± 1.64 years and mean body mass index (BMI) of 31.31 ± 0.20 kg/m2</sup> performed circle resistance exercise in the morning (8 am) on one day; after two weeks, they performed the same circle resistance training session at evening (5 pm). Blood samples were collected to determine CRP, TNF-α and IL-6 at pre-exercise, immediately post exercise, and 2 hours post exercise. Repeated measures analysis of variance (ANOVA) was used to analyze the data.

In both morning and evening, the concentrations of CRP, TNF-α, and IL-6 were significantly increased immediately after exercise (P < 0.010). Concentrations of CRP, TNF-α immediately and 2 hours after resistance exercise were significantly higher in the morning than the evening (P < 0.050). There was no significant difference in IL-6 concentrations responses between morning and evening exercise.

The findings of the present study showed that a bout of circle resistance exercise in the morning compared to evening time significantly increased post-exercise CRP and TNF-α parameters, but there was no difference in IL-6 response to exercise between the two conditions.</div>

The most important genes that exacerbate urinary tract infection are the siderophore genes, iroN and irp2. The aim of this study was to investigate the prevalence of siderophore genes irp2 and iroN in order to provide a suitable solution for the management of the bacteria carrying the mentioned gene as well as the preparation of a vaccine.

This experimental study was done in Boroujerd Branch, Islamic Azad University, Iran. 100 samples were obtained from clinical laboratories in Boroujerd City. After identification of DNA extraction by boiling method, polymerase chain reaction (PCR) was performed using specific primers.

Frequency of siderophore genes in the studied samples showed that 58 (58%) had irp2 gene, 28 (28%) had iroN gene, 4 (4%) had two genes, and 10 (10%) of both genes were negative.

The results of our study showed that the prevalence of both siderophores irp2 and iroN genes was high in the cultured samples, but siderophores irp2 had higher prevalence. Moreover, given the high prevalence of these genes in women on the one hand, and the high prevalence of broad-spectrum antibiotic-resistant bacteria on the other hand, it is likely that this and other similar studies could be a prelude to vaccine preparation for bacterial surface antigens of Escherichia coli.

Previous studies has proved that psychological factors could affect treatment adherence, in spite of this, the role of illness perception in treatment adherence is unclear. Current study was conducted in order to investigate the relations between personality characters and treatment adherence and also the role of the illness perception as mediating factor between these two.

In this cross-sectional correlation study, 87 in-patients with acute myocardial infarction, who was admitted to cardiology wards in hospitals in Isfahan City, Iran, were enrolled into this study using consecutive selection method. Questionnaire of demographics information and brief-illness perception, NEO five-factor inventory and general and specific treatment adherence were completed for the study group, and was analyzed using path analysis.

Analysis of data path showed a significant relation between conscientiousness (r = 0.263), neuroticism (r = -0.214), extraversion (r = 0.245), and openness to experience (r = 0.167) with general treatment adherence, as well as the extraversion (r = 0.309) with specific treatment adherence. Moreover, with considering the mediating role of illness perception, it showed that extraversion had strong and meaningful relation with general (r = 0.154) and specific (r = 0.139) treatment adherence.

It seems that illness perception as mediating factor could affect the relation of personality characters and treatment adherence in patients with acute myocardial infarction. So in psychological interventions, a special attention should be given to strengthen and reform of illness perception that could improve compliance among the patients.