Journal of Basic Research in Medical Sciences
Volume:2 Issue: 3, Summer 2015

To examine the hypothesis that diffusion weighted imaging (DWI) in lumbosacral region could reveal sciatic nerve course swelling that lead to lower extremity pain. The aim of present article was to find and evaluate the diffusion weighted coefficients (b-values) for scrutinizing sciatic nerve tract changes in lumbosacral region.

Lumbar area was imaged in 30 patients with lower extremity pain in one side (left or right) at 1.5 T MR with routine protocols and DWI. Two stages for processing images were generated. Distance of sciatic nerve fibers between all patients In terms of Gray level average (GLA) and Contrast average (CA) on each side were calculated by MATLAB software. An appropriate statistical test such as Paired T test was used and. P<0.05 was considered as significant

In the first stage of image processing there was no significant result in affected side rather than normal side. In the second stage, the mean b-value was significantly correlated with affected side that represent nerve swelling and the mean ADC was positively related to affected side. In b-value images, the diameter of affected side is greater than the healthy side and P<0.001 showed significant results. The CA of affected side is greater than healthy side and P<0.001 illustrated significant results. For GLA, statistics showed the greater values for affected side in comparison to healthy side and P<0.001 was significant.

Based on the results of present study, neurography is possible way to visualize early changes, such as nerve indentation and swelling, and to qualitatively evaluate affected lumbar nerves course in patients with lower extremity pains.

The main purpose of donor selection is not only the donor protection from blood donation complications but also the blood recipient not be expose to blood- transmitted diseases. This study aimed to determine the reason for exemption from donors among blood donor's who refer to Ilam Blood Transfusion Organization.

This is a retrospective and descriptive study. That all information recorded in Ilam Blood Transfusion Center in 2010-2011 (including age, gender, occupation, marital status and the exemption) were collected and data were analyzed by using SPSS software.

Research results showed that of 4005 participants, 2349 persons were exempt from blood donors. 1241 persons (31.1%) after reading message of Iranian Blood Transfusion Organization and awareness about blood donation criteria, have found that their blood is not suitable for donation. 1061 patients (26.5%) were exempted from history and physical examination, 41 (1%) After tests have been diagnosed with viral diseases and were exempt from donating blood. 1656 (41.4%) donors were healthy. The most common causes of exemption included, drug use (23.7%), hypertension (21.8%), anemia and blood disorders (15.5%), bloodletting (11.9%), cold (7.3%) and behavior risky (4.9%), respectively.

In present study, there are several causes for deferrals which most of them are temporary and they are disappear after education and proper training, these individuals could be donors.

GTPase regulator associated with focal adhesion kinase (GRAF) is a recently identified GTPase activating protein that has the tumor suppressor properties. However, the expression level of GRAF in leukemia had received less attention. The main purpose of this research was the evaluating of the expression level of GRAF in patients with acute myeloid leukemia (AML).

Ninety people participated in the research (45 patients with AML and 45 healthy persons). RNA was extracted from their blood samples and cDNA synthesized. The expression levels of GRAF mRNA were determined by QRT-PCR method.

The expression levels of GRAF mRNA were significantly lower in AML samples than the control groups. WBC count was high in down-regulated samples than up-regulated ones (P< 0.05). There was any significant difference between two groups in other laboratories parameters.

In spite of rare studies on GRAF gene expression level in patients with AML, was shown that it's down-regulated in people with AML.

Macro-ergonomics is an important factor that affects behavior, favorable performance and personnel’s efficiency that can cause conformity of employees by increasing labor and efficiency and in result decreasing employees’ stress amount. The aim of the present study was to investigate relationship between Macro-ergonomics and occupational stress in employees working in one casting industry in Isfahan.

This study was analytical-descriptive and of the type sectional that was conducted on 100 employees. To determine Macro-ergonomics status score, the Macro-ergonomics status evaluation questionnaire and the standard questionnaire of occupational stress (HSE) was used. Data were analyzed using SPSS software, version 20 and using Pearson correlation tests and regression analysis and couple-t.

Pearson correlation test showed that there was negative relation between Macro-ergonomics score and occupational stress (r= -0.62, P<0.05). Also results showed that there was adverse relation between occupational stress with all of Macro-ergonomics areas (r= -0.598, P<0.05).

According to the results, Ergonomic factors have important role in occupational stress among employees. The more effect on decrease of occupational stress was observed when using suitable strategies and correction of this aspect of the organization.

Major depressive disorder is a common mental condition associated with substantial morbidity and economic burden. Approved by the FDA in September 2013 for treatment of episodes of major depressive disorder, Vortioxetine is one of the newer options available in this important area of therapeutics.

A comprehensive literature search (PubMed, the Cochrane library, Scopus, CRD and HTA Database in January 2015) was performed, containing controlled clinical trials that vortioxetine 10 mg/d versus placebo in adults with major depressive disorder.

Six controlled clinical trials were included in this meta-analysis. There was a significant difference between the vortioxetine 10 mg/d versus placebo in the Montgomery–Åsberg Depression Rating Scale (MADRS) (P value <0.00001). The results of pooled analysis for diarrhea, dry mouth, dizziness, headache and nausea were also significant (P value <0.00001). Vortioxetine 10 mg/d versus placebo showed a significant difference for nausea, but no significant differences were observed for the other five adverse effects.

Therapy with vortioxetine was significantly associated with reduction in depression symptoms from baseline compared to placebo.

Reality therapy is a particular approach in adolescent development and independence that repeatedly emphasized on the disagreeable relationships and self-control to encourage personal growth. Unfortunately, we could not find any study in the context of effectiveness of training reality therapy concepts on parent-child conflicts and self-efficacy. Therefore, this study were done with the purpose of considering the effectiveness of training reality therapy concepts on parent-child conflict father-son and self-esteem in adolescents in Ilam province.

This study was a semi-experimental research which its statistical community consisted of all first and second grade students of Motahari and Shahriari high schools in Ilam province during 2014-2015. Nearly, 30 students were selected by a random sampling method, and assigned into intervention and control groups. To appraise dependent variable, the Murray Strauss Parent-child conflict (father-son version) questionnaire of self-concept as well as the Coppersmith self-respect questionnaire were used in the study.

The results of multivariate analyses of covariance revealed that the posttest scores of parent-child (father-son) conflict were considerably reduced in the experimental group compared with the control group (P<0.05), and the self-esteem scores in the experimental group was significantly increased than in the control group (P<0.01).

Reality therapy training program caused to diminish parent-child conflicts and escalating self-esteem in adolescents and therefore, it is recommended that this program be used to reduce parent-child, father-son conflicts and increase self-esteem in the educational, psychological and educational levels along with other programs.

Parasitic diseases could be one of the common problems of human society in any time in every place. The animals can passed this infection to human as zoonotic disease. Cats are one of the most important animals that living and eating long with human in society. Therefore feline parasitic zoonosis is threatened human health and cause death and serious disease. For the reason, the present study evaluated the current status of major canine parasitic zoonosis in this region.

Fifty stray cat, road accidentally, were collected from different location of Ilam city. Within the period of one year, their internal spacemen were checked for agent parasitic and their tissues proceeds for histopathological study.

Out of 50 stray domestic cats, 14 (28%) male and 36 (72%) were female. Ten species of internal-parasite like helminthes in majority and protozoan in minority were detected in the examined cats. Overall 48 cats (96 %) were infected with at least one of the parasites. The major parasites were as follow: Nematode (Toxocara cati 32.4%, Toxocara leonina 6.2% and Physaloptera praeputialis 4.5%), Cestoda (Dipylidium caninum 27.10%, Mesocestoides lineatus 14.2%, Taenia taeniaformis 6.2%, Joyeuxiella echinorhyncoides 8.3% and Taenia hydatigena 1.1%), and Protozoa (Isospora felis 21.2%, Haemobartonella felis 2.34%). There was no significant difference in infection rate between male and female cats.

Our result indicates that for controlling and preventing of zoonosis disease, more attention should be given to these feline infections.

A rare case of squamous cell carcinoma ex pleomorphic adenoma in maxillary sinus is presented. The patient is a 50-year-old woman presenting with a slow-progressive swelling in left side of her face that she has noticed 2 years earlier. The lesion was not painful and caused asymmetry and mild exophthalmos. Microscopic examination revealed that the tumor was composed of two components partly of a pleomorphic adenoma and partly of a squamous cell carcinoma. Immunohistochemical examination for Ki-67 and SMA and mucicarmin staining were also done and confirmed the diagnosis of carcinoma ex pleomorphic adenoma. There is no evidence of recurrence 12 months after operation.