مجله علمی پزشکی جندی شاپور
سال نوزدهم شماره 2 (پیاپی 125، خرداد و تیر 1399)

Systemic inflammation is one of the factors affecting insulin resistance. The aim of study was to investigate the effect of aerobic interval training and use of nettle supplement on Inflammation Level and glycemic control in men with type II diabetes.

A quasi-experimental study, 40 male patients with type II diabetes (Age: 42.08 ± 3.99 years; body mass index: 27.01 ± 1.62 kg /m2) were randomly selected and divided into four groups: training, supplement, training + supplement and control groups. The aerobic interval training program was performed three days a week for eight weeks. Nettle tea was consumed 10 grams daily, 15 minutes before the three main meals. For statistical analysis, paired sample t-test and one-way ANOVA statistical methods were used (P≤0.05).

There was a significant reduction was observed in FBS, HbA1C, IL-6 and CRP in training group and training + supplement compared to the control group. Also there was a significant decrease in FBS, IL-6 and CRP levels in supplement group compared to the control group (P <0.05). Also, HbA1C was significantly lower in the training + supplement group than the supplement group (P = 0.002).

Both interventional aerobic interval training and nettle supplementation seem to play a beneficial role in reducing inflammation and glycemic control, and the combination of the two methods is more effective in glycemic control in patients with type 2 diabetes.

The purpose of the present research was to study the effectiveness of cognitive behavior therapy with positive imagination of health on dysfunctional attitudes on primary hypertension in patients with dysfunctional attitudes and primary hypertension. Subjects and

The sample of the study included 40 subjects with primary hypertension (22 females and 18 males) who referred to specialist clinics in Ahwaz. They were matched of age, educational status and other criteria considered in this research, then randomly divided into two groups as experimental and control. We administered Beck and Wizeman Dysfunctional Attitudes Scale (DAS). Twelve sessions of cognitive behavior therapy with positive imagination of health for experimental group only. Finally, all subjects of two groups were assessed from dysfunctional attitudes and primary hypertension in posttest and follow up.

The results revealed that there was a significant difference between two groups in dysfunctional attitudes and primary hypertension at posttest and follow up (P<0.001). The rate of dysfunctional attitudes and primary hypertension in the experimental group were significantly decreased compared to the pretest and control group. These results persisted significantly during the follow-up period. Also, by controlling the duration of the disease, there was a significant difference between experimental and control group in terms of dysfunctional attitudes and primary hypertension, but in terms of primary hypertension, no significant difference was observed. This result suggests that the duration of the disease has no effect on the rate of dysfunctional attitudes, but does affect the primary hypertension of the groups in the follow-up period.

The results of this study suggest that cognitive behavior therapy with positive imagination of health significantly decreased the dysfunctional attitudes and primary hypertension, therefore using cognitive behavior therapy with positive imagination of health in high hypertension patients is recommended.

Asthma is a chronic and common medical illness in childhood. Chronic illnesses can be associated with mood disorders, anxiety, and behavioral disorders, as well as adversely affecting the clinical course of the underlying disease. The purpose of this study was to compare behavioral disorders in children with and without asthma referred to Masoumeh Hospital in Qom.

In this study, 67 asthmatic children as case group and 67 healthy children as control group were enrolled. The demographic and clinical information checklist and the Child Behavior Checklist (CBCL) were completed. Data were analyzed using t-test and chi-square test using SPSS 18 software.

The mean score of CBCL questionnaire in case group with 28.12 2 2.06 was significantly higher than control group with 17.33 9 9.7 (p = 0.01). Mean scores of social isolation subscales (case group: 5.83, control group: 1.18, p = 0.006), anxiety-depression (4.99 vs 2, p = 0.02), intellectual problems (8 Aggressive behaviors (5.5 vs 2.3, p = 0.003) were significantly higher in children with asthma than healthy children.

Behavioral disorders in children with asthma were significantly more than healthy children. The duration of asthma and the severity of asthma, in direct association, can predict behavioral disorders in children with asthma.

Cardiac intensive care unit patients are at risk for mental disorders such as anxiety and depression. This study aimed to evaluate the effect of lavender aromatherapy on anxiety and depression in patients with acute coronary syndrome admitted to the cardiac intensive care units. Subjects and

This randomized clinical trial was conducted on patients with acute coronary syndrome admitted to the cardiac intensive care of Namazi Hospital in Shiraz in 2014. A total of 110 patients were randomly assigned to either the Aroma or the placebo group. Before and after the intervention, the anxiety and depression levels of the patients were measured. Data analyzed by descriptive and inferential statistics using SPSS version 16.

Patients receiving the aroma showed a significant reduction in depression (P-value = 0.01) and anxiety (P-value = 0.099) compared to placebo group. Also, the effect of size on depression and anxiety was 0.52 and 0.54 respectively, which indicates a high amount of effect.

Based on the findings, aromatherapy with lavender can reduce anxiety and depression in patients with acute coronary syndrome.

This study aimed to evaluate the frequency of estrogen receptors in prostate carcinoma cells in order to better understand the relationship between estrogen receptors in malignant cells and their pathological significance.

In this descriptive cross-sectional study, tissue paraffin blocks of excised prostate samples taken from patients diagnosed with prostate adenocarcinoma and benign prostatic hyperplasia, considered as control, were studied. These patients referred to teaching hospitals of Ahvaz Jundishapur University of Medical Sciences. Clinical and demographic data of patients were extracted from hospital records. Immunohistochemical staining was performed using Anti ER monoclonal antibody.

Thirty prostate tissue specimens were found which included 20 specimens with prostate carcinoma and 10 specimens with benign hyperplasia. The mean age of patients was 69.65 yr. Estrogen receptor marker was expressed in only 25% of malignant samples. In contrast, 100% of benign samples showed ER marker expression. ER marker expression was significantly correlated with Gleason score (P =0.039).

Overall, the findings of this study indicate that the estrogen receptor is decreased in prostate malignancies and is more pronounced only in higher grade tumors.

The aim of this study was to evaluate the expression of COX2 protein in patients with colorectal carcinoma in order to better understand the pathophysiology and behavior of inflammatory factors in this disease.

In this cross-sectional descriptive study, tissue paraffin blocks of patients referring to Imam Khomeini teaching hospitals with pathological diagnosis of colorectal cancer were evaluated. Clinical and demographic data of patients were extracted from hospital records. Anti Cox2 monoclonal antibody was used for immunohistochemical staining.

In this study, 31 patients with colorectal cancer (mean age 65.1 (range 33 to 89)) were evaluated. Most tumors had grade G2 (54.8%). Tumor stage pt3 was also seen in more than half of cases. Lymph node involvement was observed in 29% of cases. The mean staining area was 34.6% (range 2 to 78%). More than half of the patients showed moderate marker expression and 6.5% had a strong positive reaction. However, 16.1% of patients were negative for Cox2 marker. We have failed to find any significant correlation of stage, grade and lymph node involvement with Cox2 expression status.

The findings of this study indicate that more than 70% of colorectal malignant tissues express Cox2 marker. However, Cox2 marker expression had no significant association with pathologic variables such as tumor grade, stage and extent of metastasis to the surrounding lymph nodes.

The purpose of the present study was to investigate the changes of malondialdehyde, dopamine and glutathione peroxidase in the hippocampus of rats with Parkinson's disease: a comparison of two types of continuous and interval aerobic exercise.

In this study, 30 male Wistar rats weighing 250 to 350 g were used. Subjects were treated with reserpine for Parkinson's disease and divided into 6 groups and 5 rats each. Then the exercises were performed for 6 weeks. At the end of training, rats were anesthetized using ketamine and xylazine, hippocampal tissue was isolated, and malondialdehyde, dopamine, and glutathione peroxidase (GPX) were measured. The results were analyzed using one-way ANOVA and Bonferroni post hoc test.

The results of this study showed that 6 weeks of interval aerobic exercise showed a significant decrease in the levels of malondialdehyde in Parkinson's model rats (p ≤0.05), but continuous exercise did not show a significant decrease (p ≥0.05), as well as continuous and interval aerobic training significantly increased dopamine levels (p ≤0.05). They showed no difference between the two types of exercise (p ≥0.05). Intermittent aerobic exercise increases glutathione peroxidase levels in parkinsonian rats (p ≤0.05). But continuous training did not have a significant effect (p ≥0.05).

According to the findings of this study, it can be concluded that interval aerobic exercise can be used to improve MDA and GPX and continuous and interval exercise to improve dopamine in Parkinson's patients.

This study was conducted to determine the relationship between maternal age during pregnancy and maternal hematological parameters and anthropometric status in neonatal.

In this study, 32 mothers aged 35 years and older (case group) and 292 mothers aged 20-35 years (control group) were examined. Maternal age and hematologic parameters were evaluated before delivery. The weight, height and head circumference were measured in infants. The relationship between prenatal age of mothers and infant’s anthropometric indices were calculated using the Pearson correlation coefficient.

The comparison between the two groups showed no significant difference in the type of delivery, history of abortion, systolic and diastolic blood pressure and hematological parameters. In addition, there was no significant difference between the two groups in the sex, weight, head circumference and height of the infants. A significant negative correlation was observed between prenatal age of mothers with the number of monocyte (Mid) cells (P <0.05), number of red blood cells (P<0.05), number of white blood cells, and granulocytes (P<0.001) in mothers. Also, a significant correlation was observed between the prenatal age of mothers with number of low birth weight (LBW) (Positively, P<0.01), weight (Negatively, P<0.01), head circumference (Negatively, P<0.001) of infants.

The results of this study showed that the number of infants with LBW increases with increasing mother's age. Also, maternal age can significantly associate with some maternal hematological parameters and the anthropometric indices of infant.

Tropical Disease Research of World Health Organization has classified cutaneous leishmaniasis as an emerging and uncontrolled disease. The aim of this study was to evaluate the epidemiology of this disease in Dasht-e- Azadegan County. Subjects and

This retrospective study was conducted in Dasht-e-Azadegan County in 2015-2019, based on patient data collection (sex, age, occupation, number and location of wounds, geographical area and season of outbreak). Data were analyzed by SPSS software version 20.

The number of patients with cutaneous leishmaniasis in the 5-year period was 1320 person, of which 720 of them were male (54.54%) and 600 of them were female (45.46%). The highest number of diseases was seen in the age group of 10-19 (23.78%) and 20-29 (23.63%) respectively. In addition, 61.74% of patients were urban and the rest were rural. Significant differences were observed between the geographical area, occupational group, and season with cutaneous leishmaniasis. About, 59.54% of patients had one wound and the most involved member was hands (28.78%). The highest seasonal prevalence was in winter and in January and February. During the period under review, the highest incidence of the disease was observed in Abu-Hamiyzeh, and overall the incidence of the disease had been decreased during these five years.

Due to the endemic nature of the disease and the prolonged activity of Phlebotomus papatasi in this county, education of high risk individuals is essential to reduce the incidence and prevent the disease.

The resilience in mothers having children with attention-deficit hyperactivity disorder (ADHD) and the factors influencing on it is an important issue which requires a comprehensive study. Apart from point of views about the negative and positive effect of having children with ADHD ,the question is why some mothers with ADHD children have much more successful performance than the others? The purpose of present study has been to identify those factors involved in resilience in mothers having children with ADHD.

In this content analysis qualitative research. Twenty three experienced resilience mothers were selected by targeted sampling through a semi-structured interview until the data were completely saturated.

By analyzing the data, four main categories and twelve sub-categories were obtained. The category of personal and psychological factors was divided into sub-categories of self-feeling, self-efficiency, sense of purposefulness, skill of problem-solving and attitudinal factors; the category of family factors was included husband support and the other family members; the category of social factors was included the interpersonal skill, social support and social awareness, spiritual powers was involved the religion belief and descriptions of Islam.

The results of this research help the professionals as well as healthcare and educational centers to formulate the necessary programs related to the mothers having children with ADHD given the identified factors to receive the required skills. Training those factors to the mothers having ADHD children will contribute to increase the mothers' resilience and to avoid experiencing any failures in their life.