فهرست مطالب

Diabetes and Obesity - Volume:13 Issue: 1, Spring 2021

Iranian Journal of Diabetes and Obesity
Volume:13 Issue: 1, Spring 2021

  • تاریخ انتشار: 1400/01/22
  • تعداد عناوین: 8
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  • Siddharth S Mishra*, Vibha Dhotre Pages 1-9
    Objective

    Study aims to compare Auditory, Visual and Postural RT among middle aged type 2 diabetics and healthy individuals.

    Materials and Methods

    A Cross-Sectional Study which included 200 Participants that met inclusion and exclusion criteria, were divided into 2 groups. Diabetic group included 100 participants who were clinically diagnosed with type 2 Diabetes and healthy group insldued 100 healthy participants. Both the groups performed Auditory Reaction Time test (ART) and Visual reaction time test (VRT) using Inquisit 4.0 computer software, Ruler drop test (RDT), Wobble Board (WB) Test and Timed up and go test (TUGT) was performed.

    Results

    Statistical analysis (independent sample T-test) revealed a significant delay in VRT (P-value= 0.001), ART (P-value= 0.001), Wobble Board Test (P-value= 0.001) and TUGT (P-value= 0.001) among diabetic group compared to healthy group. There is no significant difference in Ruler drop test (P-value= 0.919) among both the groups.

    Conclusion

    There was is a significant delay in RT among middle aged type 2 diabetic participants when compared to healthy participants. This is associated with reduced sensory stimuli from various systems and resulting in late response in diabetic group

    Keywords: Middle aged, Reaction time, Postural balance, Healthy volunteers, Gait
  • Hamed Taheri, Roya Rafaiee, Raheleh Rafaiee* Pages 10-18
    Objective

    Academic health services play an important role in the prevention and control of diabetes mellitus (DM) in Iran. This study aimed at determining the prevalence of DM-related complications and the associated risk factors among patients with DM in a university-affiliated outpatient diabetes clinic of a referral hospital in Southeast of Iran, Zahedan.

    Materials and Methods

    This cross-sectional study was conducted from January to April 2019 in an academic diabetes clinic. A total of 334 patients with DM, whose characteristics (age, sex, family history of DM, and substance abuse), as well as laboratory and clinical information, were recorded in the baseline forms, were included. The relationship between variables were assessed by Pearson’s correlation coefficient at P-value< 0.05 and using SPSS version 20.0.

    Results

    The mean age of the participants was 54.27 (±11.57) years. In these patients, DM type 2 was estimated at 99.1%, and the mean duration of the disease was 8.98 (±6.93) years. The findings showed that 77.2% of the patients had poor glycemic control. Also, 85.4% of the patients had fasting blood sugar (FBS) level >126 mg/dL. There was a significant relationship between insulin-dependent therapy and drug abuse (P-value <0.001). The prevalence of hyperlipidemia (68.9%), hypertension (50.6%), retinopathy (29.6%), nephropathy (11.7%), and neuropathy (12.3%) was also determined.

    Conclusion

    The majority of the patients (77.2%) in this study had poor glycemic control, and 69.9% of them suffered from microvascular complications, macrovascular complications, or both. Therefore, frequent visits accompanied by patient education could help to better diabetes control

    Keywords: Prevalence, Diabetes, Laboratory parameters, Diabetic complication
  • Azam Erfanifar, Seyed Mahmoud Latifi*, Hajieh Shahbazian, Armaghan Moravej Aleali Pages 19-25
    Objective

    The data on the changes in the prevalence of obesity and overweight could help policy makers to make better plans for improving the health status of people; hence, the aim of his study is to evaluate the prevalence and incidence of overweight, obesity and abdominal obesity in Ahvaz during five years.

    Materials and Methods

    Cohort study was the method of choice in this survey, conducted on 605 people aged over 20 years who were selected among the people covered by health centers in Ahvaz. The participants weight, height, and waist circumferences were measured two times in 2009 and 2014. The incidence and prevalence of obesity, abdominal obesity and overweight were evaluated. The SPSS 22 statistical software was used to analyze the data, and paired T-test to compare the level of changes. The significant level for P-value < 0.05.

    Results

    Among 605 people aged over 20 years, the prevalence of overweight, obesity and abdominal obesity in 2009 and 2014 were respectively: overweight (40% and 38.50%), obesity (26.90% and 27.10%), and abdominal obesity (26.80% and 33. 90%).This prevalence increased from 11.70% to 14.90% in men and from 39.90% to 50.50% in women. The incidence of overweight, obesity and abdominal obesity were respectively 102.50, 22.50 and 76.5 per 1000 person’s year in Ahvaz people.

    Conclusion

    The findings of our study showed that the prevalence of overweight, obesity and abdominal obesity in adult population in Ahvaz is high. Also, the prevalence of obesity and abdominal obesity in women is higher than men; therefore special attention must be paid to this issue in women. Also the age groups 35-64 years are higher risk

    Keywords: Overweight, Obesity, Abdominal obesity, Prevalence, Incidence, Ahvaz
  • Mahdi Abdolkarimi, Mohammadali Morowatisharifabad, Mohammad Asadpour* Pages 26-32
    Objective

    Regular physical activity (PA) is one of the most effective recommendations to prevent diabetic complications. However, the reported level of PA is low in this group. This study evaluates intervention based on the implementation intention (II) theory, to improve the level of PA and the health of patients with diabetes.

    Materials and Methods

    This randomized control study was conducted on 124 patients with type 2 diabetic. The participants were randomly assigned in to two groups. PA level was measured by using International Physical Activity Questionnaire (IPAQ). The Rockport test was used in order to measure Maximal oxygen consumption volume (vo2max). In the intervention group, Individuals were asked to identify details of the behavior of PA and their own strategies for removing the barriers of exercise. Post-tests took place 3 month later. Normal distributed data were analyzed using two independent and paired sample T-test. Wilcoxon, Mann-Whitney tests were used to compare PA level.

    Results

    The results showed that although the median level of PA after the intervention (396) had increased. This difference was not statistically significant (P-value= 0.12). Also, after three months vo2max score (19.91) was not significantly different from before (P-value= 0.30).

    Conclusion

    Intervention based on II had no significant effect on level of PA in patients with type 2 diabetes. Using multiple methods, as well as incorporating it with motivating interventions should be investigated to increase the level of PA in this group.

    Keywords: Implementation intention, Physical activity, Cardiovascular fitness, Patients, type 2 diabetes
  • Nader Moghaddam Dizaj Herik, Naimeh Moheb*, Abdol Ali Banaeifar, Nasser Agha Mohammadzadeh Pages 33-39
    Objective

    The aim of the present study was to examine the effectiveness of Acceptance and Commitment Therapy (ACT) combined with aerobic exercise (AE) on anxiety symptoms, insulin resistance (IR) and lipid profile in women with T2DMmellitus (T2DM).

    Materials and Methods

    In the present study, 60 T2DM women with a mean age of 33.5 (± 3.52) years were selected from the patients who were referred to the specialized clinic Petroleum Industry in summer 2020. They were randomly divided into four groups of ACT (n=15), AE (n=15), ACT combined with AE (n=15), and the control group (n=15). Intervention programs were performed for 10 weeks, and then indices were collected before and after the intervention using blood tests and Beck Depression Inventory.

    Results

    ACT led to a significant decrease in anxiety and LDL (P-value: 0.001). Moreover, AE significantly reduced the anxiety index and increased HDL (P-value: 0.001). In addition, the effect of ACT and exercise significantly reduced anxiety (P-value: 0.001) and LDL index (P-value: 0.03) and also increased HDL (P-value: 0.03). However, indices of blood glucose, insulin, insulin resistance, total cholesterol, and triglycerides did not indicate any significant changes in the intervention groups as compared with the control group (P-value<0.05).

    Conclusion

    According to the obtained findings, the use of psychological intervention along with AE could lead to a significant change in the symptoms of anxiety and some lipid indices in T2DM women. Also caused a non-significant improvement in glycemic index and can be regarded as a solution for diabetics

    Keywords: ACT, Aerobic training, Anxiety, Lipid profile, Diabetes
  • Ghasem Ahmadi Nasab, Reza Delavar*, Hamed Taheri Pages 40-47
    Objective

    Renal failure is a complication of diabetes. It can be the risk factor of cardiovascular disease. This study aimed to evaluate the effect of exercise course and Aloe-Vera supplementation on renal function and lipid profile in type 2 diabetes mellitus (T2DM) patients.

    Materials and Methods

    This is a clinical trial double blind with pre-test and post hoc test analyses with a control group. The studied population included a group of T2DM diagnosed patients among whom 24 men (40-60years) were selected voluntarily and purposefully and were classified into three groups by balanced block randomization method, exercise(E), exercise + supplement (E+S), and control (C), (n=8/group). Combined exercise was planned in two 12-minute repetitive sets with 70% 1RM. Then the participants ran for two 10- minute sets with 70-75% maximum heart rate intensity on treadmill. E+S participants consumed 500 mg/day Aloe Vera for 6 weeks. Obtained data by SPSS-19 software were analyzed using co-variance analysis method with Bonferroni post hoc test (P-value<0/05).

    Results

    Results showed that E and E+S significantly improved GFR (P-value=0.011) and E with or without Aloe-Vera consumption decreased creatinine levels (P-value=0.042) and increased HDL levels (P-value˂0.001). The results demonstrated that LDL and TG levels showed no significant difference in reaction to the combined exercise and supplementation.

    Conclusion

    Combined exercise along with Aloe-Vera supplementation has had significant effect on improving renal factors and lipid profile of T2DM diagnosed patients

    Keywords: Combined exercise, Type 2 diabetes, High density lipoprotein, Low density lipoprotein, Creatinine
  • Parisa Homayounpour, Mohammadreza Seirafi*, Sahar Ghare Pages 48-56
    Objective

    The growing worldwide prevalence of overweight and obesity, despite treatment strategies remain the health problem. Over the past decade, increasing attention has been paid to psychological factors and a potentially comprehensive, multimodal skills-based treatment. The purpose of this study was to evaluate the efficacy of dialectical behavior therapy (DBT) on weight loss in obese women with emotional and behavioral disorders.

    Materials and Methods

    In this quasi-experimental study, statistical population from convenience sampling consisted of 42 obese women with body mass index (BMI) more than 29.9 kg/m2 divided in 3 groups, behavioral, emotional and control. Descriptive and analytic statistics were computed according to demographic information, emotional eating scale and Dutch eating behavior questionnaire. Intervention included 13 sessions of 1.5hr group therapy, DBT-skills training from April to September 2019. Mixed-effect modeling ANOVA with repeated measurements was performed by statistical analyses, IBM SPSS version 24 to study changes in variables over time.

    Results

    The results demonstrated that the emotional such as anger, anxiety and depression, significantly decrease during the study period. (P-value<0.001) As well as behavioral eating demonstrated significant improvement in restrained eating and decrease in emotional and external eating behaviors right after the end of intervention while trial group experienced significant weight loss.

    Conclusion

    The present study provides some evidence that DBT-skills training can be effective in decreasing problematic eating behaviors, emotion dysregulations, decreasing BMI

    Keywords: Dialectical behavior therapy, Obesity, BMI, Behavior eating, Emotional eating
  • Maryamalsadat Hashemi Taklimi, Saeedeh Shadmehri* Pages 57-64
    Objective

    Mitochondrial content and function are important determinants of oxidative capacity and metabolic efficiency of skeletal muscle tissue. The aim of this study was to investigate the changes in mitochondrial dynamic factors (mfn2 and drp1) following high intensity interval training (HIIT) and moderate intensity continuous training (MICT) in obese male rats.

    Materials and Methods

    In this experimental study, 40 male wistar rats after inducing obesity with high fat diet (for 10 weeks), eight rats from the high-fat diet group (O) and eight rats of the standard dietary group (C) were sacrificed and other obese rats were randomly divided into three groups: obesity control (OC), MICT and HIIT groups. The HIIT protocol includes 10 bouts of 4-minute activity with intensity of 85-90% vo2max and 2-minute active rest periods and MICT protocol with intensity of 65-70% VO2max with covered distance was matched to that of HIT protocol for 12 weeks and 5 sessions per week. Protein levels of mfn2 and drp1 soleus muscle were measured by Western blot. For analyzing the data, One-way ANOVA and Tukey post hoc with SPSS–23 and the significance level was P-value≤ 0.05.

    Results

    Induction of obesity was associated with a significant decrease in soleus muscle mfn2 and drp1 (P-value= 0.001). The intervention of HIIT and MICT significantly increased of mfn2 and drp1 compared to control group (P-value= 0.001). Also, mfn2 and drp1 were significantly higher in HIIT compared to MICT group (P-value= 0.001).

    Conclusion

    It seems that HIIT and MICT increase the mitochondrial dynamic factors in skeletal muscle, and the effects of HIIT are significantly higher

    Keywords: High intensity interval training, Moderate intensity continuous training, Mitochondrial dynamic, Obesity