فهرست مطالب

Razavi International Journal of Medicine - Volume:4 Issue: 3, Summer 2016

Razavi International Journal of Medicine
Volume:4 Issue: 3, Summer 2016

  • تاریخ انتشار: 1395/04/11
  • تعداد عناوین: 8
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  • Kambiz Kamyab, Mahtab Rahbar *, Ali Ghannadan Page 1
    Background

    Spitz Nevus is an infrequent acquired melanocytic nevus. There is still a challenge for dermatopathologists in dis- tinguishing spitz nevus from malignant melanoma particularly in adults since there is no immunohistochemistry or molecular markers which differentiate Spitz Nevus frommelanoma.

    Objectives

    The aim of this study is to make clear what clinico-histopathological features of Spitz Nevus are in order to reduce malpractice due tomisdiagnosis.

    Methods

    In the present study, a series of twenty two patients have been reviewed who were diagnosed with Spitz Nevous based on proved histopathology features between the years 2009 - 2013. The patients were evaluated for demographic parameters like age, sex, clinical differential diagnosis, cutaneous location of tumor, tumor diameter, subtype, symmetry,maturation, upper cleft- ing of melanocytic nest, shoulder phenomena, epidermal hyperplasia, type, kamino body,mitotic rate , inflammatory infiltration, pagetoid spread and regression.

    Results

    In our study, 45% of patientswere younger than 10 years old. The average age of patientswas 1411.37. Male to female ratio was 1.44. The commonest location was head and neck. Spitz nevus was the first clinical differential diagnosis in 20% of patients. The commonest variant type was conventional type and then polypoid and desmoplastic types. The mean size of nevi was 0.81  0.59mm. About 59% of nevi shows epithelioid cytologic features. Other histologic parameters fromthemost to the least frequency were symmetry (100%), maturation (100%), epidermal hyperplasia (77.3%), kamino body (68.2%), subtype (compound 68%), mitotic rate (63.6%), clefting (59%), inflammatory infiltration (54.5%), pagetoid spread (18.2%), shoulder (37.5%) and regression (9.1%).

    Conclusions

    We tried to hifhlight some clinical and histopathological features which are distinguishing Spitz nevus from other melanocytic nevi evenmalignantmelanoma.

    Keywords: Spitz Nevus, Clinical Findings, Histopathologic Findings
  • Leila Bigdelu, Golsa Tabatabaei Yazdi, Fariba Alizadeh Sani, Azra Izanloo, Zahra Rezai Yazdi, Afsoon Fazlinezhad * Page 2
    Background

    Pulmonary arterial hypertension (PAH) is a leading cause of death in systemic sclerosis (SSc) patients. Early detection of systolic failure in SSc patients will facilitate early treatment and improve the survival rate of these patients.

    Objectives

    In this study, besides studying the RV function in SSC patients, attempts have beenmade to find a new possible nonin- vasive echocardiographic test for early diagnosis of systolic failure as a PAH complication.

    Methods

    30 patientswith at least a 2-year history of diffuse SSc confirmed by an expert rheumatologistwere enrolled in this study. All the patients underwent transthoracic echocardiography by an echocardiologist. Fractional area change (FAC) of the right ven- tricle (RV), tricuspid annular plane systolic excursion (TAPSE), RV lateralwall strain and strain rate (Base,Mid, Apex), RV-EDD and RV pressure with respect to inferior vena cava (IVC) diameter as well as Left Ventricle’s Ejection Fraction (LVEF) were evaluated.

    Results

    The prevalence rate of PAH was reported 36.6% in this study. There was no significant relationship between LVEF and RV parameters. LVEF was found to be significantly higher in women whereas RV strain turned out to be higher inmen. Besides, there was a significant relation between pulmonary arterial pressure (PAP) and Basal (P = 0.03),mid RV strain (P = 0.002), RV strain rate (P = 0.001) and RV diameter (P = 0.02). Also, an inverse relationwas observed between RV systolic (P = 0.01) and diastolic functions (P = 0.007) with PAP. In addition, no significant relationship was found between LVEF and bodymass index (BMI) and RV parameters (P > 0.05). Moreover, Apical RV strain and LVEF were found to be higher inmales and females respectively. Furthermore, a significant relationshipwas found between RV strain and age (P = 0.027). Finally, the results did not show any relationship between RV systolic and diastolic functions and gender.

    Conclusions

    This paper states the likely advantages of strain and strain rate echocardiography in identifying patients withmore diffused and severe SSc and the need for further longitudinal studies based on thementionedmethod for early diagnosis ofmyocar- dial impairment.

    Keywords: scleroderma, Systemic Sclerosis (SSc), Pulmonary Arterial Hypertension (PAH), Right Ventricle (RV ) function, Systolic Failure, Tissue Doppler Imaging (TDI), Strain, Strain Rate Echocardiography
  • Atefeh Nemati-Karimooy *, Majid Akbari, Fatemeh Zourmand Ghasemi Page 3
    Background

    Achieving the characteristics of effective teaching can play an undeniable role in assurance of education.

    Objectives

    The aimof this studywas to assess the relationship between some teachingmicro skills during classroomteaching and the level of students’ learning.

    Methods

    At the beginning of this cross sectional study, a list of professors’ behavioral-verbal characteristics during classroom teaching, whichmight lead to amore efficient learning, was prepared. These items were checked according to the check list by two students after attending the class. At the end of each session, an examwith appropriate validitywas held to evaluate the amount of learning. The correlation between the students’ scores and the teaching skills of the professor was analyzed through SPSS software ( = 0.05).

    Results

    A significant correlation was found between “Absence of mumble in the class” (P = 0.015), “fun atmosphere in the class” (P = 0.032), “notmerely reading the slides by the professor” (P = 0.003), “mentioning the objectives at the beginning of each session” (P = 0.011) and “lack of voice monotony” (P = 0.023), and the increase in the mean of students’ scores. However, there was not a significant relationship between designating a break time during teaching period (P = 0.120) and “the rate of teaching” (P = 0.774) with themean of student’s achieved scores.

    Conclusions

    According to the conditions of this study, the ability to control the class in terms of absence of mumble, establishing a fun atmosphere, not merely reading the slides by the professor, mentioning the objectives at the beginning of each session and lack of voicemonotony increase the learning level in classroomteaching.

    Keywords: Education, Professor, Student, Learning, Teaching skills
  • Hadi Abbassi *, Arezoo Zarebi, Ahmad Heydarnia Page 4
    Background

    The services that student counseling center present play an important role in students’ psychological health. There- ore,measurement of services quality can contribute to a higher quality of these services.

    Objectives

    This studywas conducted in order tomeasure service quality of student counseling center at the university of Bojnord.

    Methods

    In this cross-sectional descriptive research participated 253 students who referred to student counseling center at the university of Bojnord fromMarch to June 2015. A questionnaire adapted to SERVQUALmodel was used to collect the data. Wilcoxon signed-rank test was used to analyze the data.

    Results

    The result of this study showed that there were some differences between students’ perceptions and their expectations of counseling services quality (Z = -12.91; P < 0.0001). The result also indicated that therewere significant differences between students’ perceptions and expectations in all of the five dimensions of SERVQUALmodel. Themost significant gapwas related to the tangibles and the less significant one was related to sympathy dimension.

    Conclusions

    By studying the gap between perceptions and expectations of students fromcounseling services, we can provide the base for developing appropriate programs for the improvement of counseling services.

    Keywords: Student Counseling Center, Service Quality, SERVQUALModel
  • Mohammad Reza Hassibian *, Sepideh Hassibian Page 5
     Context

    Distributing health care services in remote and rural areas have become a major health problem for many developing countries. Telemedicine presents solutions to developing countries for better disease prevention, diseasemanagement, emergency services and practicingmedicine in areaswith limited access to healthcare services and facilities. Although thewillingness of devel- oping countries to accept telemedicine and incorporate it into their health care systems is rising, due tomultidisciplinary and com- plicated characteristics of telemedicine, they will face challenges and barriers which will slow down their progress. This literature review attempts to explain the benefits, categories and barriers for acceptance and implementation of telemedicine in developing countries.

    Evidence Acquisition

    This studywas conducted in 2016. Themain questionwas howis the general attitude to the acceptance and use of telemedicine in developing countries and what problems they are facing for the use of telemedicine. To find the solutions, we searched articles in two main databases, PubMed and Scopus, with the keywords and expressions related to the subject of the study (developing countries, telemedicine, tele-health, barriers, challenges, adoption, and acceptance). Totally, 103 articles were extracted. Duplicate articles andarticlespublishedbefore 1998were eliminatedandthe remaining oneswere screenedfor eligibility in accordance with subject of the study. The result was 47 articles from PubMed and 5 articles from Scopus. This review is based mainly on preliminary results, opinions and predictions. As limitations of our study, we limited ourselves to PubMed and Scopus databases and also reviewed articles only in English language.

    Results

    The study did not find any article that totally disagrees with the implementation of telemedicine in developing countries. Most of the articles contain positive points associated with the use of telemedicine with respect to the barriers and challenges.

    Conclusions

    Despite hopeful progresses in telemedicine, developing countries are facingmany problems in theirway toward suc- cessful application of telemedicine. High cost and cultural resistance are considered as themain barriers for developing countries in their approach to apply telemedicine. Developing countries must be fully aware that investment in telemedicine will not in- evitably yield clinical or economic benefits in short time. Theymust consider barriers and various outcomes of telemedicine before accepting and applying it.

    Keywords: Telemedicine, Developing countries, acceptance, advantages, Barriers, Challenges
  • Leila Zare, Fakhri Tajikzadeh, Yadolla Zargar, Seyede Fateme Sajadi * Page 6
    Background

    Self-esteemis a stable sense of personalworthiness. There is insufficient evidence fromthe available research to fully determine the relationship between self-esteemand early trauma.

    Objectives

    This is a correlational study aims to investigate the relationship between early traumas as a predictor of negative self- esteemby controlling the effect of maladaptive schemas in 11-13 year-old-student sample.

    Methods

    292 people (201 females, 91 males) with mean age of 12.33 were selected via multistage random sampling. Participants completed questionnaire on children’s depression inventory (CDI), childhood trauma questionnaire (CTQ), schema inventory for children (SIC) and provided demographic information. Analyzing data was done using correlation and stepwise regressionmeth- ods.

    Results

    The results showed that emotional neglect and physical abuse are the best predictors of negative self-esteem. Additionally, the results revealedno evidence ofmaladaptive schemasmediating the relationshipbetweenearly trauma andnegative self-esteem.

    Conclusions

    In general, the findings showed that emotional neglect and physical abuse are the best predictors of negative self- esteemin children and explain a considerable variance of survival index. Our findings also demonstrate thatmaladaptive schemas do not have any significant effect on the relationship between trauma and negative self-esteem.

    Keywords: Negative Self, Esteem, Early Trauma, Maladaptive Schema
  • Farah Ashrafzadeh, Ghasem Sadeghi Bajestani *, Mohammad Reza Hashemi Golpayegani, Ali Sheikhani, Paria Hebrani Page 7
    Background

    Autismspectrumdisorder (ASD) is a severe behavioral disorder characterized by pervasive impairments in social in- teractions, deficits in verbal and nonverbal communication, and stereotyped, repetitive patterns of behaviors and interests. Despite recent advances in identifying some genes that may cause autism, its underlying neurological mechanisms are uncertain. ASD is best conceptualized by considering the neural systems thatmay be defective in autistic individuals.

    Objectives

    Here,we aimto describe a potentialHierarchicalmodel for ASD. This interesting presentedmodel is based on excitatory and inhibitory characteristics of cortico-cortical networks.

    Methods

    Jasonmodel is one of themodels applied to produce EEG in cortical areas. In thismodel, a cortical area ismodeled with three subpopulations including: excitatory pyramidal cells (output), excitatory interneurons groups, input inhibitory interneuron groups bymeans of output connections (output connections are limited to cortical planes). The presented hierarchicalmodel for autism spectrum disorder (HMASD) is based on Jason model. HMASD is a hierarchical model of cortico-cortical networks as well as an excitation/inhibition model in sensory, mnemonic, social and emotional systems. In HMASD there are three kinds of outer connections including forward, backward and lateral connections, that their power is controlled by coupling parameters.

    Results

    HMASD raises the possibility that ASD is related to excitation/inhibition imbalance in cortico-cortical networks. HMASD parameters are possible way for quantization imbalance quality.

    Conclusions

    Themost effected parts in ASD are lateral connections of HMASD. Two-sided connections which are completely sym- metric become more active, and cause extra synchronization. On the other hand, due to special characteristic of two-sided con- nections and their ability to simulate the same phased dynamics, they cause unnatural asymmetry in children’s EEG signal. These results are consistent with previous findings suggesting the association of EEG abnormalities in ASD with functional impairment of information interacted in cortical connections.

    Keywords: AutismSpectrumDisorder, HierarchicalModel, Brain Behavior, Asymmetry
  • Glenn Borchardt, Mehdi Dadkhah * Page 8