فصلنامه طب مکمل
سال یازدهم شماره 1 (پیاپی 38، بهار 1400)

Aging is associated with some changes in the structure and function of the liver. Increased collagen deposition as well as decreased mitochondrial function are among these changes. Therefore, the aim of this study was to evaluate the effect of exercise and vitamin C intake on PGC-1α, MFn1 and collagen deposition in elderly rats.

The present study was an experimental study with a control group. Twenty-five male rats (Wistar) aged 24 weeks (280-320 g) were randomly divided into 5; 1 young control group, elderly group + resistance training, elderly group + liposomal vitamin C, elderly group + resistance training + liposomal vitamin C and old age control group. In the groups receiving liposomal vitamin C, each group was given daily liposomal vitamin C (100 mg/kg/day) by gavage based on body weight. One-way analysis of variance was used to examine the difference between the groups and Tukey post hoc test was used to determine the difference between the groups. All studies were performed at the level of α≤ 0.05.

The findings of this study showed that aging significantly reduced the expression of PGC-1α and MFn1 and increased collagen deposition in the liver tissue of elderly rats (P = 0.001). However, in the resistance training group with vitamin C consumption, a significant increase in PGC-1α expression was observed in comparison with the elderly control group (P = 0.001). However, there was no significant change in MFn1 expression. Also, in the resistance training group in comparison with the elderly control group, vitamin C group in comparison with the elderly control group and resistance training group along with vitamin C consumption in comparison with the elderly control group a decrease in collagen deposition was reported (P = 0.001).

Resistance training with vitamin C consumption in elderly rats reduces collagen deposition in liver tissue and also increases PGC-1α expression.

The goal of any health system is to improve health and reduce disease, mortality and disability in society. Razi is one of the most prominent practitioners. His works, including "Al-Hawi", are considered one of the most expensive scientific heritage of Iran and the world. He was successful in producing science, innovation and expanding knowledge. He had a tremendous and wide impact on the completion of various sciences including medical science in theory and practice.Pregnancy and childbirth Pregnancy is one of the valuable topics dealt with in the Book of Alawi. Techniques and special cares have been used for labor in various studies. One of these techniques is the  " Valsalva maneuver " - Straining with closed glottis and holding breath - which is commonly used in the second stage of labor in many countries. The Valsalva maneuver was first described and recorded by an Italian physician named Antonio Maria Valsalova in 1704.However,Razi  referred to this technique and recommended that it be used for difficult childbirths in Al-Hawi book.

 Women health has a vast meaning and it is constituted of physical, mental, social, cultural, and moral health. It is also affected by social, political, economic, and biological factors. This study investigates the influence of honey on womenchr('39')s reproductive health because these days the traditional medicine, nutrition therapy, and the use of functional foods are important in taking care of our health and in disease prevention and cure, and because that women health is so important.

 This paper is a narrative review article researching the effects of honey on womenchr('39')s reproductive health in related English and Persian articles published between the years of 2005 to 2020.  For gain these articles I searched the Cochran , Embase, Pubmed , Medline , Sid , Medlib ، Scopus, ISI, Google Scholar. Through a comprehensive search and according to the inclusion criteria, a total of 76 articles were found, which by removing duplicate and overlapping articles in databases, in the first stage, 25 articles remained, and finally, after applying the inclusion and exclusion criteria, 13 articles were studied.

 The articles show that honey is effective in improvement of Cesarean section wound and Episiotomy, reduction the intensity of early Dysmenorrhea, decrease the amount of bleeding, the duration of menstruation, and the distance between two successive menstruation; also, in nausea, vomiting, headache, and other menstruation pains. It is also effective in parturition progress and vaginal candidiasis cure.

 Honey can be a complimentary medicine for prevention and cure of a lot of disease related to women whether alone or along with other related medicines.

Anxiety is mostly considered as one of the biggest issues in humans’ lives and its complications are obvious in their lives. On the other hand, the medical methods that are used to control anxiety can cause physical complications or drug dependence. Therefore, anxiety control is one of the important actions of nursing that can be handled by non-pharmaceutical methods such as aromatherapy. This study is done in order to compare the effects of aromatherapy using the essence of Rosa damascene and Citrus Aurantium on elderly peoples’ anxiety.

In this semi-experimental study 60 elder people were chosen by stochastic numbers and using the Excel RandBetween application after Obtain informed written consent. The elders inhaled the %10 Rosa damascene essence for three nights. Then, after a month of clearing period, they were under aromatherapy with the %10 Citrus Aurantium again. In each period, the variable of anxiety was measured by the Geriatric Anxiety Scale (GAS). The data were analyzed using the Paired sample T-Test, Independent T-Test, and the Wilcoxon Signed-Rank test in the SPSS version 25 with the statistical significance of lower than 0.05.

Although the anxiety grade was improved during both aromatherapy courses (p<0.001), the variations of anxiety grades in the two mentioned courses of Rosa damascene and Citrus Aurantium didn’t have a statistical significance difference (p=0.729).

Aromatherapy using Rosa damascene and Citrus Aurantium essence can take part in elderly anxiety treatment.

Oxidative stress causes DNA damage and apoptosis and leads to cardiovascular disease. The aim of this study was to evaluate the effect of a course of aerobic exercise with hypoallergenic supplement of Tribulus terrestris on mitochondrial oxidative stress markers of cardiac tissue in rats toxicated with hydrogen peroxide.

To implementation of this experimental research, 42 male wistar rats randomly were divided into 7 groups include 1) Control (toxicated with hydrogen peroxide without extract), 2) Aerobic exercise, 3) Aerobic exercise - Tribulus terrestris extract 5mg/kg, 4) Aerobic exercise - Tribulus terrestris extract 10mg/kg, 5) Tribulus terrestris extract 5mg/kg, 6) Tribulus terrestris extract 10mg/kg, 7) Healthy control. All groups received 100 mg/kg body weight of hydrogen peroxide for 14 days intraperitoneal. Rats in supplemented groups received Tribulus terrestris hydroalcoholic extract with doses of 5 and 10 mg per day by gavage method. Aerobic training was performed on a treadmill at a speed of 23 m/min, 30 min/day, 5 days/week for eight weeks. 24 hours after the last training session, rat heart tissue was collected. Data were analyzed by Independent t-test, two-way ANOVA and Bonferroni post hoc test at the P<0.05. 

Tribulus terrestris extract and mixed intervention of tribulus terrestris extract with aerobic training led to significant increase in levels of O-6-methyl guanine-DNA-methyl transferase, Prooxidants-antioxidant balance (PAB) and Cytochrome C Oxidase, as well as significant decrease in adenosine triphosphate (ATP) and Malondialdehyde (MDA) the heart tissue of rats compared to the control group poisoned with hydrogen peroxide (P<0.05).

It seems that iintervention of regular aerobic training and the various doses of tribulus terrestris extract is a moderating factor in mitochondrial biogenesis and is effective in reducing the DNA damage in heart tissue and the lower dose has more benefits.

One way to educate patients is to use instructional videos. The use of educational videos has been introduced as a valuable tool in patient education and counseling, especially preoperative education to reduce anxiety and control vital signs.

The aim of this study was to determine the effect of educational video on preoperative anxiety in patientchr('39')s candidates for eye surgery by Fico method.

The present study was a clinical trial study in which 160 patients who was candidates for cataract surgery by Fico method by simple random sampling participated in the intervention and control groups with written consent. Data collection tools were demographic characteristics questionnaire and Spiel Berger standard questionnaire. SPSS software version 23 and descriptive and inferential statistical tests were used to analyze the data. Significant level was considered 0.05.                                  

The mean age of patients in the intervention and control groups was 58.63± 7.68 and 62.32 ±9.15 respectively. The mean of overt and covert anxiety before the intervention in the experimental group were 48.92 ± 4.86, 50.97 ±6.27 and in the control group 48.88± 8.35, 46.31 ±7.80 and After the intervention in the experimental group were 37.95 ±7.04, 44.20± 6.79 and in the control group were 48.72 ±7.46 and 44.10 ±8.23, respectively. There was a statistically significant difference in the score of overt and covert anxiety before and after the intervention in the intervention group  (P =0.05). Comparison of the mean score of overt and covert anxiety showed that there was a statistically significant difference in the score of overt and covert anxiety after the intervention in the intervention and control groups (P = 0.000).

The short educational video leads to the reduction of hidden and overt anxiety in patients who are candidates for cataract surgery by Fico method. It is necessary to train nursing staff in order to educate patients through educational videos and to provide facilities in order for nurses to interact with patients and educate them.

Hospitals and medical centers are places that provide health services that with their special facilities in increasing patient satisfaction, reducing stress and promoting health and improving patients and training of medical staff and also plays a key role. The aim of this study was to identify some examples of traditional medicine treatment centers.

This research is a review article in terms of purpose, Also, by using the descriptive survey method, while presenting how to use design variables in these centers, it tries to improve the physical and mental states of patients. In order to collect data, studies of traditional medicine sources as well as Internet data were used in a library manner.

By examining factors such as sufficient light, colors, decorations and motifs, natural materials and diversity in creating green space and nature, the impact of architecture on the better performance of these centers by introducing case studies and using the items recommended in traditional medicine to design Letchr('39')s pay for these centers.

it seems that the sources of traditional medicine have a lot of emphasis on the impact of the environment on human health. And creating a suitable bed for being in space, controlled the balance of mood and found a specific architectural pattern, which due to the importance of these parameters and the psychological impact it has on people can be placed by patients to improve and even non-patients to Strengthening mental states improved the health of people in the community.

Malaria is one of the most important parasitic diseases and one of the important health issues especially in tropical and subtropical areas of the world. .The importance of this disease is due to its high prevalence, significant mortality, as well as drug resistance and, side effects of current drugs in treatment. Venom is a complex mixture of active pharmaceutical ingredients. The purpose of this study was to investigate the anti-Plasmodium falciparum activity of the purified fraction of Iranian cobra snake venom by Real -time PCR.

After Lyophilized venom was purified for determining  inhibitory concentration 50% against Plasmodium falciparum 3D7 in vitro, in different dilution plates, different fractions obtained from Iranian cobra snake venom were adjacent to Plasmodium falciparum in the ring stage. The degree of parasitemia was determined. Finally, the effective fraction with antiplasmodial properties was identified.

The results showed that the most effective fraction had IC50 0.026 μg/mL on P. falciparum in vitro (p<0.001) .

The results were promising considering the anti-Plasmodium effect of the active fraction of Iranian cobra venom in the mentioned concentration and motivated the continuation of advanced research in this field.