مجله علمی پزشکی جندی شاپور
سال بیستم شماره 5 (پیاپی 134، آذر و دی 1400)

Infection of the blood and cerebrospinal fluid can have irreparable consequences and even death. In the present study, the prevalence of bacteria causing blood and cerebrospinal fluid infection and their antibiotic resistance in hospitalized patients was investigated.

In this present descriptive-cross-sectional study, the results of all blood and cerebrospinal fluid samples were sent for culture from the hospitalized patients of Golestan Hospital in Ahvaz in the first six months of 2019 were examined. Relevant information was extracted from patients’ medical records.

In this study, 12.17% of blood culture were positive and 7.6% of cerebrospinal fluid culture were positive. The most common bacteria causing blood infections were Staphylococcus Coagulase Negative (32.5%), Klebsiella (24.1%) and Pseudomonas (21.7%), and the most common bacteria causing cerebrospinal fluid infection were Klebsiella (30.9%), Streptococcus. group D (Enterococcus) (20.6%) and pseudomonas (15.5%). The highest bacterial resistance was observed for Ampicillin, Ceftriaxone, Cefazolin, Cefixime and Cefotaxime antibiotics, and the highest sensitivity was observed for Meropenem, Colistin, and Levofloxacin antibiotics.

Since the bacterial resistance pattern is always changing, it is suggested that before starting any empirical treatment in infectious diseases, sensitive antibiotics for common bacterial agents are recommended for a more efficient treatment.

The fetal period is an important stage in a person’s life. Exercise during pregnancyhas been considered as a positive factor in preventing chronic diseases in adulthood. The aim ofthis study was to investigate the role of maternal high intensity exercise before and during pregnancy onserum levels of lipid profile of adult offspring.

Twenty-four rats (170-200g) were divided into three maternal groups: Control (C),exercise Before Pregnancy (BP) and exercise before and during pregnancy (BDP). Exercise performed beforepregnancy for six weeks and during pregnancy for three weeks; one minute with 80% -95% vo2maxswitching with two minutes of active recovery (65% vo2max) for five days/week. After end of the trainingbirth process and breastfeeding, the offspring were divided according to theirs’s mother group and theywere kept until adult age. The serum levels of LDL, HDL, TG and Cho were measured by enzymic method.

The one-way ANOVA result showed that maternal exercise before and during pregnancy significantlyreduced LDL, Cho and LDL/HDL cholesterol ratio in male (P=0.03, P=0.2, P=0.04) and female(P=0.00, P=0.02, P=0.04) offspring.

This finding suggests that maternal high-intensity-interval training as an appropriate environmentalintervention can help to improve the health of the next generation.

Leukemia usually begins in the bone marrow and leads to the production ofa large number of abnormal white blood cells.The goal of this study was to investigate changes on UCA1lncRNA and AKT target, gene expression alternations, regulating PI3K / AKT signaling pathway in JurkatE6.1 Acute Lympholastic Leukemia cell line under treatment with thiosemicarbazone complexes (nickel).

First, thiosemicarbazones complex Ni and 6MP was provided in different concentrations(0.5,1,2,5 μM) and (1,5,10,25 μM) and the jurkat E.6.1 Cancer cells were treated with mentioneddoses at (24-48-72 hours) after cell passage. Next RNA extraction and cDNA synthesis were performedand the expression of UCA1 and AKT gene were appraised by Real Time PCR. Finally, the resultswere analyzed by Rest Software.

UCA1 showed a significant decrease during 24 hours of treatment with 6mp at concentrations(1,5,10 and 25 μM) (P<0.001). In nickel,a significant decrease at 72 hours was observed at concentrations(2 and 5 μM). In the AKT in treatment with 6mp at 24 hours At concentrations (5,10 and 25 μM)And all concentrations (1,5,10 and 25 μM) at 72 hours showed a significant decrease (P<0.001). In nickelat concentrations (0.5,1,2 and 5 μM) at 24 hours Decreased expression was observed, This decrease isnot statistically significant at a concentration of 0.5μM.at concentrations (2 and 5 μM) Significant reductionsat 48 and 72 hours were observed (P<0.001).

UCA1 and AKT expression changes after treatment with 6mp and nickel depend on drugtiming and concentration.UCA1 in 6MP treatment at 25μM and 24 hours,in treatment with nickel at5μM and 72 hours , AKT in 6mp treatment at 25μM and 72 hours , In treatment with nickel at 5μM and24hours,It had the highest effect on the cell due to gene expression.

Acute gastroenteritis is a highly prevalent disease in children. Various factorsmay causes seizure in children with gastroenteritis. This study was designed to determine the frequency,clinical characteristics and causes of seizure in children younger than 5 years with acute gastroenteritisadmitted to Ahvaz Golestan hospital.

In a retrospective descriptive study based on hospital records , 339 children under5 years old who were admitted to Ahvaz Golestan hospital during 2016 - 2017 were assessed. Patientswith underlying neurological disorders were excluded and the recorded information of patients withseizure was reviewed.

Out of 339 reviewed cases, 59 patients (17.4%) had seizures, most prevalent in13 to 24 monthsage group (28.8%). In 74.6% of cases, type of diarrhea were dysentery. 64.4% had mild dehydration.Encephalopathy was detected in 1.7%, shigellosis in 6.8%, hyponatremia in 32.2% and hypernatremiain 3.4%. Seizures in 52.5% of cases were considered as febrile Seizure. Diagnostic criteria of benign convulsionsassociated with mild gastroenteritis (CwG) were present in 5% of patients. 79.7% of cases hadgeneralized seizures. In comparison, a significant relationship was observed between the febrile andnon-febrile groups only in the variable of diarrhea type.

The results show that fever and electrolyte imbalances and among infectious agents, Shigellaare important causes of seizures in patients with gastroenteritis. In patients with dysentery, seizures aremore likely.

Military personnel are exposed to some work stress due to their working conditions,which causes negative effects on their quality of life. The aim of this study was to investigate theeffect of sixteen weeks of functional training on quality of life and mental health of military personnel.

In the present Quasi-experimental research, 150 military personnel from Andimeshkand Dezfoul cities were selected by random sampling method and divided in two training andcontrol groups. Exercise was performed for sixteen weeks of functional training, three sessions per week,and each training session lasted about 60-90 minutes. T-test was used for statistical analysis.

After the training period, there was a significant improvement in the quality of life sub-comparisonsof physical function, physical role, emotional role, energy and vitality, social function, physical pain,and general health in the functional training group compared to the control group, but the differenceNo significance was observed in cognitive health between the two groups. In the subscales of mentalhealth, a significant improvement in physical symptoms, anxiety symptoms and sleep and social dysfunctionwas observed in the functional exercise group compared to the control group, but a significantdifference in changes in depressive symptoms was observed in the functional exercise group comparedto the control group. Failed.

According to the findings of the present study, it can be said that functional exercises haveimproved the quality of life of military personnel by improving their mental health.

Acute myocardial infarction refers to a reduction or amputation of coronaryartery circulation leading to myocardial necrosis. BDNF is expressed in atherosclerotic arteries, vascularsmooth muscle, and endothelial cells and is involved in angiogenesis, the inflammatory response, andapoptosis of myocardial regeneration after infarction. The aim of this study was to evaluate the effect ofa cardiac rehabilitation period on changes in BDNF levels and functional capacity in patients with acutemyocardial infarction.

The present study was performed on 30 men with acute coronary syndrome witha pretest-posttest design and the samples were randomly divided into experimental and control groups.The experimental group performed a cardiac rehabilitation program for 6 weeks. The control group didnot perform any training during this period. Before and after the rehabilitation program, BDNF levelswere measured by the American Diaplus Kit in terms of picograms per milliliter and participants’ functionalcapacity by a modified Bruce test. Analysis of covariance was used to compare BDNF levels andfunctional capacity of cardiac rehabilitation and control groups.

Data were analyzed by covariance. the results showed that cardiac rehabilitation training had asignificant effect on increasing BDNF levels and functional capacity (P≤0.05).

Based on this study, it can be said that cardiac rehabilitation exercise program can play animportant role in improving the physical and physiological condition of patients with acute myocardialinfarction. Data were analyzed by covariance and the results showed that cardiac rehabilitation traininghad a significant effect on increasing BDNF levels and functional capacity (P≤0.05). In general, it can besaid that cardiac rehabilitation exercise program can play an important role in improving the physical andphysiological condition of patients with acute myocardial infarction.

The prevalence of hearing loss in infants with a risk factor is higher than ininfants without a risk factor. The aim of this work is determine the prevalence of hearing loss and identifythe most significant risk factors for hearing impairment in neonates hospitalized at neonates unit.

A total of 450 infants admitted to the neonatal unit of Abuzar hospital in Ahvazwere evaluated for hearing in October 2020 to April 2020. The hearing screening tests performedwere Transient Evoked Otoacoustic Emissions (TEOAES) and the automated auditory brain stem response(AABR). Risk factors include birth weight less than 1500g, prematurity, family history of hearingloss, consanguineous marriage, hyperbilirubinemia, mechanical ventilation for more than 5 days,asphyxia, autotoxic drugs, sepsis, hypoglycemia and Apgar less than 5 were in one minute after birth.

twenty neonates (4.4%) had different type of hearing loss. MechanicalVentilation more than 5 days, sepsis, asphyxia, hyperbilirubinemia and Apgar<5 were considered riskfactors of hearing loss.

The prevalence of hearing loss in neonate with risk factor is significant that raises the needfor hearing screening using TEOAE and AABR simultaneously. It is recommended that children withhearing loss risk factors be evaluated for hearing periodically.

The use of antioxidant supplements improves and reduces oxidative stressfactors following intense intense exercise. Exhaustion was performed in female athletes.

14 female athletes with an age range of 20 to 28 years and a maximum oxygenconsumption of 42-52 m/kg/min in a quasi-experimental design randomly divided into two groups receivingcoenzyme Q10 supplementation and placebo (5 mg/kg body weight). Were. After 14 days ofcoenzyme Q10 supplementation, the subjects performed an intense, debilitating activity. Urine sampleswere collected in three stages (baseline, before and 24 hours after exhaustive activity) to determine theconcentration of 8-OHdG and MDA.

There was a significant difference of 62% in the increasing response of urinaryOHdG-8 to an exhaustingaerobic exercise session (P = 0.003). However, the 2% difference in the increasing urinary MDAresponse of the supplement and placebo groups was not significant after the last quasi-competitiveaerobic training session (P = 0.7).

According to the results of the study, two weeks of high-pressure aerobic training causesDNA damage and lipid peroxidation in female athletes, and supplementation with Q10 helps preventthe 8-OHdG response of female athletes after a strenuous high-pressure aerobic training session andreduces DNA damage. Become athlete

Hydatid cyst is a worldwide zoonotic disease caused by the larval stages ofEchinococcus granulosus. The aim of this study was to investigate the demographic, clinical and radiologicalcharacteristics of hydatidosis patients undergoing surgery in hospitals in Ahvaz during.

This study is a retrospective descriptive cross-sectional study based on the informationrecorded in the patients' files. Data were analyzed using SPSS software, descriptive statistics andChi-square test.

Of the 107 patients with a mean age of 36.78 years, 42.1% were male and 57.9% were female.The highest frequency was related to the age group of 31-40 and the lowest was related to the patientsunder 10 years old. 52.3% lived in the rural areas and 47.7% lived in the urban areas. In 70.1% of thepatients, liver was involved and recurrence was reported in 14%. In 59.8% of the patients, only one cystwas reported and in 40.2% more than one cyst was reported. The cysts size was 10 to 180 mm and about50% of the patients had CE2 cysts. The diagnostic method of all patients was imaging techniques anddrainage method was the most common method used.

This study showed that hydatid cyst in Khuzestan Province is still one of the important healthproblems that raise the need for educational programs based on the prevention and control of parasiticinfections, especially parasites transmitted by dogs. Observation of 14% recurrence also raises the importanceof choosing the appropriate surgical method by surgeons.

Background and Objectives Most renal patients have various oral manifestations such as halitosis, xerostomiaand pale mucosa. The purpose of this study was to evaluate the relationship between periodontalstatus and chronic renal disease.Subjects and Methods In this case-control study, the case group was divided into three subgroups, whichincluded renal patients before dialysis, patients undergoing hemodialysis, and patients after renal transplantation,each of which included 23 patients. The control group also included 38 healthy individuals interms of renal function. After obtaining the consent form and completing the questionnaire, the amountof plaque index, gingival index, papillary bleeding index, probing depth, loss of clinical attachment, gingivalrecession and gingival enlargement were measured T-student,chi-square. and Anova was used toanalyze the data.Results The plaque index, gingival index, papillary bleeding index, probing depth, loss of clinical attachmentin groups with chronic renal disease were higher than the control groups (P< 0.001) but there wasno significant difference in gingival recession and gingival enlargement between control group and casegroups (P> 0.05 ) . These parameters were not significantly different between the groups with chronicrenal disease (P> 0.05).Conclusion Periodontal disease is more common in patients with chronic renal disease, therefore, specialperiodontal treatment considerations and regular dental examinations should be added to the treatmentplan of these patients.