Journal of Applied Chemical Research
Volume:16 Issue: 4, Autumn 2022

New derivatives of furo[2,3-f]quinoline derivatives in high yields using multicomponent reaction of the  2-amino-4-hydroxyacetophenone,  isopropenylacetylene,  aldehydes  and  malononitrile  or  ethyl cyanoacetate in the presence of catalytic amounts of Fe3O4/KF/Clinoptilolite@MWCNTs magnetic nanocomposites  using  ionic  liquid  as  green  solvent  at  room  temperature  were  synthesized.  This catalyst could be employed several times in these reactions and have the main role in the yield of the product. The synthesized compounds have NH group in their structure and for this reason, have good  antioxidant  activity. Our  procedure  for  preparation  of furo[2,3-f]quinoline  derivatives has some advantages such as low reaction time, the product with high yields, and simple separation of catalyst and products.

The environmental pollution caused by drug antibiotic waste presents a foremost concern in the ecosystem, as  high  levels  of  these  antibiotic  drugs  after  consumption  when  released  into  the  ecosystem,  biological samples  are  accumulated  and  are  producing  overall  contamination.  Consequently,  the  need  for  selective, sensitive, fast, easy-to-handle, and low-cost early monitoring detection systems is growing. In this study, we used a prepared Albizia Lebbeck Leaves-capped AgNPs sensor to illustrate examples of friendly biosensors with  their  real  application  fields for  the  sensitive  detection  of the  metronidazole  drug  in  various  matrices such as human fluids by kinetic spectrophotometric method. The calibration curve was linear in the range of (0.02 to 10.0 µg L−1). The standard deviation of less than (3%), and detection limits (3S/m) of the method (0.02 µg L−1in time 8 min, 367 nm) were obtained for sensor level response Albizia Lebbeck Leaves-capped AgNPs with (95%) confidence evaluated. The artificial neural network model was used as a tool very low for determining  mean  square  error  (MSE  0.061)  for  metronidazole  drug  by Albizia  Lebbeck  Leaves-capped AgNPs sensor. The observed outcomes confirmed the suitability of recovery and a very low detection limit for  measuring  the  metronidazole  drug.  The  method  introduced  to  measure  metronidazole  drugs  in  real samples  such  as  urine  and  blood  was  used  and  can  be  used  for  other  drugs  environmental  pollution  and hospital samples.

Albizia  Lebbeck  Leaves-Capped  Silver  Nanoparticles  (ALLC AgNPs)  were  constructed using a green and sustainable method and used as an effective adsorbent for the removal of butylparaben  (BP)  dye  from  an  aqueous  solution.  The  possible  mechanisms  for  the fabrication of ALLC AgNPs were also investigated and discussed. The proposed adsorbent was characterized and identified using FT-IR, XRD, and SEM techniques. For investigating the  influence  of  affective  factors  like BP dye  concentration,  pH, adsorbent  dosage,  and sonication time on the removal process and achieving optimum conditions, central composite design  (CCD)  based  response  surface  methodology  (RSM)  was  applied.  To  investigate  the adsorption  mechanism  and  kinetic  of the removal  reaction,  different  isotherm  and  kinetic models were used. The obtained results proved the applicability of fabricated adsorbent as an ideal material for the treatment of pollutants and especially dye molecules.

In  this  paper,  a  highly  selective  sample  cleanup  procedure  combining  molecular  imprinting  and solid phase extraction (MI-SPE) was developed for the isolation of toxic bentazon in surface water. The molecularly imprinted polymer (MIP) was prepared using bentazon as the template molecule, methacrylic acid as the functional monomer, and ethylene glycol dimethacrylate as the cross-linking monomer. The  bentazon  imprinted  polymer  was  used  as  a  selective  sorbent  for  the solid-phase extraction  of  bentazon  from  surface  water.  An  offline  MI-SPE  method  followed  by  highperformance liquid chromatography was also established. To evaluate the applicability of the MIP for separation and determination of bentazon by HPLC, general parameters for SPE including the number of  loading  solvents,  washing  solution  and  eluent, and  pH  of  the  sample  were  optimized following a step-by-step approach. The calibration curve was linear in the range of (0.05 to 0.6 µg L−1).  The  standard  deviation  of  (2.2  %)  and  detection  limit  of  the  method  (0.05  µg  L−1)  were obtained for sensor level response. It was shown that recoveries up to approximately 97.0 % from spiked surface water samples could be obtained.  It was demonstrated that the proposed MI-SPEHPLC method could be applied to the direct determination of bentazon in surface water.

In this work, the synthesis, spectral characterization, DFT calculations, and catalytic activity of the new Pt(II) complexes with the ligand derived from benzimidazole derivatives have been described. The new heterocyclic ligands were obtained from the reaction of o-amino-ketones with hydrazine hydrate  in  high  yieldandPt(II)  complexes prepared  from  the  coordination  of  the  new ligands  to Pt(II)  cation. The  new  compounds  have  been  characterized  by  spectral  and  microanalytical  data.The DFT  calculations  at the  B3LYP/6-311+G(d,p) level were also  applied to  gain  further insight into the geometry of Pt(II) complexes. The catalytic activity of Pt(II) complexes in Biginellireaction was also examined as heterogeneous catalysts. The results showed that the 3,4-dihydropyrimidin-2(1H)-ones have been synthesized, in excellent yields, under solvent-free conditions, by reaction of tert-butyl acetoacetate, alcohol, arylaldehydes, and urea in the presence of Pt(II) complexes as an efficient and heterogeneous and catalyst.

Nowadays, the production of bio-oil and chemical intermediates from renewable energy sources is very  important  because  of  growing  concerns  about  climate  and  environmental  changes.  In  this work, the thermal liquefaction of Sambucus ebulus (Danewort plant) is studied with a focus on the yield  and composition  of the produced bio-oil.  The produced bio-oil was characterized by  FTIR, GC, and GC-MS analyses, and more than 35 different chemical components were identified in it. About  60  w%  of  the  produced  bio-oil  is  composed  of  five  chemical  components  of acetic  acid (21.29%), pentanoic acid (19%), acetone (10.64%), neophytadiene (5%), and α-pinene (4.4%). The effects of various process parameters of reaction temperature, time, and concentration of solution media on the yield and composition of products were studied. The maximum yield of the produced bio-oil is about 42% in a temperature of 160°C, a reaction time of 2 h, and 0.75 V% of ethyl acetate in the solution media.