فصلنامه نوید نو
پیاپی 82 (تابستان 1401)

Fatigue is one of the most common side effects which is known as one of the most important stressors and is expressed as a debilitating complaint. Despite advances in pharmaceutical and non-pharmaceutical fields, this problem still exists, so the present study was conducted to determine the effect of lowering the temperature of dialysis solutions on fatigue in these patients. This two-group randomized clinical trial was performed on 60 patients undergoing hemodialysis in Mashhad hospitals in 2017. The temperature of the dialysis solution was set at 35°C in the intervention group and 37°C in the control group. fatigue of patients in both groups was measured by the Piper scale before and after the intervention. Data were analyzed using SPSS 18 statistical software and t-test, Mann-Whitney and paired t-test. The results showed that fatigue in patients undergoing cold hemodialysis was significantly reduced in the postoperative phase (P <0.05). Cold hemodialysis solution (35°C) can help reduce fatigue in hemodialysis patients. Therefore, it is recommended that care providers use this method to reduce the complications of hemodialysis in these patients.

  This study aimed to model the causal psychological adaptation to illness in cancer patients based on emotion regulation and self-compassion with the mediating role of spiritual health.

 The present study was applied for purpose and correlational research. The statistical population of the study was patients aged 18 to 65 years with breast, blood, stomach, and intestinal cancer referred to the oncology ward of Omid and Imam Khomeini hospitals in Urmia in the first half of 1400. 250 people were selected. Data collection tools included a short form of a Cancer Adaptation Questionnaire, an Emotion Regulation Process Strategies Questionnaire, a Self-Compassion Scale, and a Spiritual Health Questionnaire. In order to analyze data, the Pearson correlation coefficient test and structural equation modeling, SPSS software version 23, and Amos and bootstrap were used.

 According to the results, strategies focused on the precedent of emotion regulation (B = 0.372) had a significant direct and positive effect, strategies focused on the emotion regulation response (B = -0.555) had a significant direct and adverse effect, and compassion. They (B = 0.383) have a direct positive and significant effect on psychological adjustment to the disease. The results of the model fit indices also showed that spiritual health has a mediating role in the relationship between emotion regulation and psychological adjustment to illness but does not mediate in the relationship between self-compassion and psychological adjustment to illness.

  Emotion regulation and self-compassion directly affect mental adjustment to disease and the mediating role of spiritual health is significant.

To understand the social and individual effects of the disease and to decide on the allocation of health resources, it is necessary to recognize the economic burden of coronary heart disease (COVID-19). However, there is limited data in this area. The aim of this study was to estimate the diagnostic and treatment costs of patients with or suspected of having Covid-19 disease admitted to hospitals in Eastern Iran.

This descriptive and analytical retrospective study was performed using data collected from 2980 patients admitted to 30 hospitals from February 2020 to April 2021 in Iran. To collect the data, a suitable data collection tool was designed to record the details of resource usage. A multivariate regression analysis was performed to examine the relationship between treatment costs and socio-demographic, disease severity, and underlying diseases. Data were analyzed using Excel 2017 software and SPSS version 21 .

The cost of hospitalization per patient was 5433500 Rials, of which 74% was paid by social health insurance systems, 19% by the government and 7% by patients. The largest components were the cost of hoteling (37%) and medicine (36%). The 4 subscales predicted age, sex, underlying disease, and severity of 48.6% of the cost variance.

Understanding the economic consequences of diseases can help policymakers in planning to reduce out-of-pocket payments and planning for financing. Since Covid-19 is an emerging disease and there is no definitive cure for it,discovering an effective drug may change medical costs and reduce the length of hospital stay, thus significantly reducing treatment costs.

Secondary metabolites of plants such as phenols and flavonoids can neutralize free radicals and antioxidant and cytotoxic activities of plants are related to their polyphenolic compounds. Antibiotic resistance has become a major problem in the treatment of infectious diseases and led to the usage of medicinal plants. The purpose of the current study was to investigate the total phenolic and flavonoid compounds of Lavandula angustifolia and Melissa officialis, and evaluate their antibacterial effects on Staphylococcus aureus and Escherichia coli. Two extraction method of lyophilization and the water bath method were used in the extraction of Lavandula angustifolia and Melissa officialis.  Folin-ciocalteu and aluminum chloride methods were used for the determination of total phenolic and flavonoid compounds and microdilution broth and disc diffusion methods were used for the evaluation of the antibacterial effect. The results showed that the total phenolic compounds of Lavandula angustifolia with the amount of 24 ± 0.04 mg /g DW using the lyophilization method and methanol solvent and the total flavonoid compounds of Lavandula angustifolia with the amount of 17.85 ± 0.011 mg /g DW using leophilization and ethanol solvent were the highest amounts among others. Methanol extract of Lavandula angustifolia was the most effective extract with a 9.5 and 7.5 mm zone of inhibition and on Escherichia coli and Staphylococcus aureus respectively. It can be concluded that Lavandula angustifolia and Melissa officialis contain phenolic and flavonoid compounds that can be used as medicinal plants in the treatment of infectious diseases caused by Staphylococcus aureus and Escherichia.

Mutations in the Adenomatous Polyposis Coli gene can cause colon cancer. Colorectal cancer is the growth of cancer cells in the colon or rectum. The aim of this study was to analyze mutations in the rs1255190244 gene point in the APC gene in patients with colorectal cancer in Tehran province.

From 2019 to 2020, 100 samples of 6-10 ml per patient were collected from patients with colorectal cancer who were definitively diagnosed. Then DNA of each sample was extracted and after checking the quality of the DNA by electrophoresis, the required primers were designed. In the next step, the amount of rs1255190244 polymorphism in the APC gene was investigated by Tetra ARMS PCR method. Finally, the results of the analysis and significance level (P <0.003) were considered with SPSS software.

The results of this study show that the incidence of colorectal cancer at the rs1255190244 gene point in the patient group compared with the control group with P0.003> is significantly associated with the incidence of colon cancer.

From the results of this study, it can be concluded that rs1255190244 polymorphism can be used as a marker to prevent colon cancer, but further research is needed to investigate several other formations.

Influenza is an acute respiratory disease that has a high prevalence in the cold seasons of the year. Prevention is the first line to deal with the increase in its prevalence. Therefore, the aim of this study was to investigate the knowledge, attitude, and practice of medical students of the Islamic Azad University of Mashhad about the influenza vaccine.

This study was performed on 148 medical students. . In this study, students were randomly selected and after recording demographic information, knowledge, attitude, and performance were also recorded. For sampling, a questionnaire consisting of 4 parts was used in which students had to answer 8 demographic questions, 8 awareness questions, 7 performance questions, and 17 attitude questions. Mann-Whitney and Kruskal-Wallis statistical tests were used to compare data.

The results of the present study showed that medical students' knowledge and positive attitude towards influenza are high, but on the other hand, their performance is very low. It was also found that awareness with higher cross-section and performance was directly related to vaccination history.

Due to the poor performance of students regarding influenza, holding classes by the medical staff periodically on influenza, especially in the seasons when there is an epidemic, is necessary and reduces the incidence of influenza epidemics in physicians and as a result, the effects of the flu are reduced.

population of older people is increasing in the world. Elderly care needs increase therefore, hospitalization increases too. Attitudes of nurses and nursing students toward older people affect the quality of medical care. The aim of this study was to assess the attitudes of nurses and nursing students toward the elderly. this study is a descriptive study of 160 nurses and nursing students of Neyshabur who were selected using purposive sampling. Data were gathered by a questionnaire consisting of two parts: demographic information and Kaplan questionnaire of attitude toward elderly and were analyzed by SPSS software ver. 17 using a Pearson correlation, t-test, and one-way ANOVA. In this study, the mean score of attitude was 110/88 of 240. It was showing 93% of nurses and nursing students had a neutral and (9/1%) had a negative and only 5% had a positive attitude. The majority of nurses and nursing students had a neutral attitude toward the elderly, which shows more attention to nurses and nursing students' education to improve their positive attitude.

. Assessing nurses' learning and functional skills on a regular basis and at regular intervals is important and requires the use of an appropriate method. The purpose of this article is to investigate the application of Kirk Patrick evaluation method in the effectiveness of nursing programs.

Search for articles in Persian in Sid, Magiran and Iranmedex databases with keywords of nursing and Kirk Patrick evaluation model and search in external sources using PubMed, ProQuest, Science Direct databases with kerk Patrick evaluation model keywords and Nursing was done in combination and separately and 44 articles were obtained which were selected and reviewed after reviewing the articles that were more relevant. 21 articles were selected and reviewed, of which 15 articles were in Persian and 6 articles in English.

Kirk Patrick model has been used as a method of evaluating the effectiveness of nursing studies in a simple way and at the first or maximum second level especially in our country. But the educational effects diminish as we get closer to the third and fourth levels, However, level 3, especially 4, which examines changes in behavior or consequences, has been used sparingly due to the difficulty of assessment.

Kirk Patrick evaluation method, along with other traditional methods, provides a new method for managers and educators that can be effective in evaluating the impact of training and it is better to use this model in four levels of evaluation.Keywords: Nursing, Evaluation and Kirk Patrick Model

Evaluation is essential to ensure the success of the organization. Approach Orinted-Management is one of the most important approaches to serving managers who are responsible for planning, implementing, and evaluating programs. The CIPP model has been distinguished from other models due to its comprehensiveness, continuity and, also the purpose of this model, which is a decision guide in program management (but, there is not enough knowledge about it). Therefore, in this article, the CIPP model and its components are studied.

This is a narrative review article. First, the keywords of evaluation models, approach oriented-management, and CIPP model were searched in available databases including Google Scholar, Science Direct, PubMed and SID, also, textbooks of management and educational evaluation were assessed in 1980-2021. Finally, 23sources including English and Persian books and articles were used to collect

CIPP stands for four different dimensions of the model, which respectively are: Context, contextual evaluation and indicates the extent to which the context is conducive to program formation. Input, this indicates the evaluation of the input. It is a tool for identifying and evaluating competitive applications and can best meet identified needs. The process represents the process evaluation that evaluates and guides the implementation of projects. Product refers to output evaluation. This step, measures, interprets, and judges project results and interpret their merit, value, importance, and correctness.

CIPP model is one of the oriented-management models and helps managers and decision makers to successfully implement plans and how to achieve their aims. This model is recommended as a framework to guide the concept, design, implementation, and evaluation of training programs, systematically

In recent years, great strides have been made in the field of autoimmune diseases. In this article, we review the autoimmune diseases in pregnancy.

The findings of the current narrative review article were obtained through searching on valid medical sites including PubMed, Scopus, Web of Science and using the Google Scholar search engine without time limit until the end of 2021, with the "autoimmune disease and pregnancy" keywords.The inclusion criteria were English-language articles in the field of autoimmune diseases with more prevalence or complications in pregnancy included rheumatoid arthritis, multiple sclerosis, systemic lupus erythematosus, antiphospholipid syndrome, Sjogren's syndrome, systemic sclerosis, and systemic vasculitis. Exclusion criteria were lack of access to the full article, documentation including commentary and letter to the editor. The results obtained from the title and abstract of the articles were checked by two evaluators.

These diseases show different reactions to pregnancy, so that some are cured, others remain unchanged, and several different types of it may worsen during this period. The reaction of autoimmune diseases to the hormonal and immunological changes of pregnancy shows the different pathophysiology of each disease. Proper consultation with relevant experts is the right solution for these people.

Women should be informed about the possible risks of this type of pregnancy and the use of some medications during this period. Because the activity of this disease during pregnancy can be problematic, it is necessary to have a rheumatologist during pregnancy and even after, along with obstetricians