Journal of Alternative Veterinary Medicine
Volume:1 Issue: 2, 2017

Disorders in Lipid production are one of the most common problems associated with diabetes seen in approximately 40% of patients. In this study, the effects of alcoholic extract of Alhagi maurorum on the serum levels of lipids in Streptozotocin-induced diabetic rats are investigated. For the purpose of this experimental research, 42 male Wistar rats were divided in 6 Groups of seven: the control, diabetic sham and 4 experimental groups. Diabetic sham received 70 mg/kg Streptozotocin once at the beginning of the experiment; the experimental groups 1 and 2 daily received 250 and 500 mg/kg Alhagi maurorum alcoholic extract respectively; the experimental groups 3 and 4 first received Streptozotocin once, and then a daily dose of 250 and 500 mg/kg extract. Oral administration of alcoholic extract continued over a period of two months. 48 hours after the last administration, blood samples were prepared and used for measurement of serum levels of triglycerides (TG), total cholesterol (TC), LDL cholesterol and HDL cholesterol. Serum levels of triglyceride and LDL Cholesterol in the diabetic sham compared to the control group showed a significant increase (p<0.05). On the other hand, serum levels of triglyceride and LDL cholesterol in the experimental group 2 (500 mg/kg extract) compared to the control group demonstrated a significant decrease (p<0.05). Also, serum total cholesterol concentration in the experimental group 1 (250 mg/kg extract) compared to the control group indicated a significant reduction, while HDL cholesterol increased significantly in this group (p<0.05). A significant decrease was observed in the serum levels of triglyceride and LDL cholesterol in the experimental group 4 in comparison with diabetic sham, whereas concentration of HDL cholesterol in experimental Group 3 increased significantly (p<0.05).Due to itsantioxidant properties, alcoholic extract of Alhagi maurorum can reduce Streptozotocin toxicity leading to an improvement in Serum lipid profiles of diabetic patients.

Probiotics are regarded as live microorganisms that provide health benefits when consumed. In the present study, the potentiality of producing foods containing probiotic bacteria with milk, yoghurt and ginger bases was evaluated. The goal was to determine the effects of different doses of ginger on the growth of two probiotic bacteria, Lactobacillus acidophilus and Bifidobacterium bifidum (together) in milk and yoghurt. The products were then examined in terms of pH, acidity, microbe counting and persistence. In day 14, the production quantities of the products were evaluated by sensory method. The results of the questionnaires (administrated to 30 people) in statistical–descriptive test were analyzed using SPSS software. It was observed that the control sample had the best taste. The bioability of probiotic bacteria was measured by direct counting method. Product permanence was determined within 21 days. It was revealed that the increased concentration of ginger had a positive effect on the growth of the probiotic bacteria in probiotic milk and yoghurt. To evaluate the effect of ginger on the amount of the probiotic yoghurt protein, the control sample and the yoghurt sample containing 3% ginger were tested. As the results revealead, the amount of protein in the sample with 3% ginger was more than the control sample.

For the purpose of this study, the antimicrobial effects of Zosima absinthifolia extract were tested on Staphylococcus aureus (S. aureus) and Escherichia coli (E. coli). Dried seeds of Zosima absinthifolia plant (100 g) were powdered and soaked in a sufficient amount of water and the extraction process was done using a soxhlet apparatus. The obtained extract was then condensed in a rotary evaporator, transesterification process was applied and the resultant product was dehydrated completely.Using GC-GC/MS instruments, it was then analyzed. The extract contains essential ingredients including n-octanol, germacrene D, β-caryophyllene, α-pinene, limonene, octyl acetate, caryophyllene oxide and n-octanal. The extract was used to determine its antimicrobial effect. Culture medium was prepared and the test was performed by disk diffusion method. The preliminary results showed that the extract has antimicrobial effects on both bacteria. This suggests that the plant can be used in future as an effective substance in the treatment of infections caused by these bacteria.

In spite of advances in the management and prevention techniques as well as strategies for diarrhea treatment, it is still a very common and costly disease affecting the small ruminants. The present study aimed at determining the prevalence of Escherichia coli (E.coli) in under 1 month old goat kidsand lambs with diarrhea in some livestock husbandries in Kazeroun city using culture method and utilizing herbal medicines instead of antibiotics. It has been done according to increasing use of antibiotics and consequently, an increase in antibiotic resistance and different susceptibility to E.coli in different areas in the world. In order to investigate the effect of hydroalcoholic extract of mint plant on goat kids and lambs diarrhea, 100 lambs and 100 goat kids with diarrhea were collected from sheep husbandries in Kazeroun. The enrichment media,selenite F Broth and MacConkeyAgar(Mac)were used for isolation.In this study, all isolated strains showed resistant against antibiotics as ampicillin and tetracycline, and were susceptible to antibiotics such as streptomycin, gentamicin, nalidixic acid, cefixime, ciprofloxacin, nitrofurantoin and chloramphenicol. The halo diameter formed by hydroalcoholic extract of mint was 10 mm, demonstrating a low susceptibility of this bacterium to the mint extract. Generally, the findings revealed that the hydroalcoholic extract of the mint hadantimicrobial properties and would be a good alternative to chemical drugs.

Doxorubicin (DOX) has a wide spread use in cancer chemotherapy and Zingiber officinale (ginger) has androgenic property and effects on fertility. The aim of the present study was to investigate the protective effects of Alcoholic extract of ginger on reproductive toxicity induced by DOX in male rats. In this experimental study, 56adult Wistar male rats were randomly divided into 7 groups of 8. The extract was orally administered an hour after intraperitoneal injection of DOX. DOX injection was carried out once a week for four weeks. On the day 29, testes were removed, fixed, sectioned, stained and examined histologically by light microscope. According to the findings, DOX caused an increase in interstitial space and deformation of cells in DOX group. Conversely, the number of spermatids, and leydig cells were significantly (p<0.05) decreased compared to the control group. Moreover, concomitant consumption of ginger alcoholic extract and DOX significantly (p<0.05) improved the induced toxicity. It was concluded that ginger alcoholic extract could prevent DOX toxic effect on testicular structure and therefore improve male reproductive activities

Of the nine chemical compounds identified in the Carum Copticum extract, thymol, γ-terpinen, and parasaymn are considered as the main compounds utilized as antiemetic, anti-asthma, anti-nausea, and spasmodic, locally used in the treatment of rheumatic pains with therapeutic effects on skin diseases, mental disorders, and genitourinary diseases. The recent scientific studies have confirmed the antiseptic impact and decreasing effects of blood cholesterol in this plant. For the purpose of this study, 72 male Wistar rats were divided into 6 groups as control, sham, and experimental groups (1 to 4). While the control group received no treatment, sham group received 2/0 ml of distilled water and experimental groups (1 to 4) took daily 200, 400, 600 and 800 mg/kg aqueous extract of C. copticum as intraperitoneal injection, respectively. After a lapse of 16 and 32 days, rats blood samples were taken. The kidneys, belonging to rats died during blood sampling after day 16 and the rats remained alive after the day 32, were removed and their uric acid and renal histology were examined. The collected data then were analyzed using SPSS statistical software package. In this study, statistical tests such as one way ANOVA, and post hoc Duncan were carried out. P-value of less than 0.05 was regarded as statistically significant (p<0.05). The findings revealed that the use of aqueous extract of C. copticum in a low dose and short and long terms results in a body weight loss and with a moderate and high dose only in long term leads to a body weight loss. Regardless of the dose, the use of such extract in short and long terms increases the kidney function. In all groups, the kidney tissue in short and long terms was completely normal with no damage. As a conclusion, this study demonstrates that the use of C. copticum extract, with no adverse effect on renal tissue, causes an increase in kidney function, though the effects of these extracts will be somehow different in details in short and long terms.