مجله دانشکده پزشکی زابل
سال پنجم شماره 4 (پیاپی 17، زمستان 1401)

Quality of life refers to people's understanding of their position in terms of culture, value system in which they live, goals, expectations, standards and priorities. The use of online health services can affect the improvement of people's understanding of health. The purpose of this study was to determine quality-of-life and its correlation with receiving online health services among middle-aged people in Kashan in 2019.

This is a cross-sectional study that was conducted on middle-aged people in health centers. The samples were 293 people who were randomly selected. Data collection was done with questionnaires on the ability to use health services and quality-of-life. Data analysis was done with Chi-square, Fisher's Exact tests, Independent samples t-test, ANOVA, Pearson's correlation coefficient and linear regression tests.

The average age of 293 participantswas 47.5 ± 6.99 with a range of 40-60 years. The average work experience was 23.11 ± 8.01 and the average use of the Internet per week was 26.2 ± 20.29 hours. The quality-of-life of 70.3 percent of the participants was average. Linear regression analysis showed that the ability to use services on the health line was predictive (β = 0.363 and p value < 0.001) and explained 14% of the variance of quality of life (p value < 0.001).

The ability to use online health services is related to the quality of life of middle-aged people. Therefore, in order to improve the quality of life of middle-aged people in the society, necessary interventions are recommended to increase the use of online health services.

Single umbilical artery is the most common developmental malformation of the umbilical cord. Its prevalence increases by multiple pregnancy, velamentous cord insertion, older maternal age, cigarrete smoking, maternal diabetes, hypertension or epilepsy. Since ethnic and genetic factors have been contributed to single umbilical artery occurrence and there is no similar study in Iran, we decided to evaluate fetuses with single umbilical artery diagnosis and describe maternal and fetal characteristics.

This was a retrospective cross sectional study conducted on pregnant women having fetuses diagnosed with single umbilical artery at gestational age of 18 to 24 weeks referring to the perinatologist during 2019-2022. Data was analyzed by appropriate analytic tests were applied.

During study period, 67 fetuses had been diagnosed with single umbilical artery. Mean values of maternal age, gestational age, body mass index were 32.29 ± 5.83 years, 18.89 ± 1.57weeks, and 26.46 ± 4.54 kg/m2, respectively. 59.7% of fetuses were male and 40.3% were female. 33 cases (49.2%) had no other associated malformations and choroidal cysts and intra-cardiac echogenic focies were the most prevalent abnormalities. As well, in 16 cases more than one malformation were detected. In cases with isolated single umbilical artery, no intrauterine growth retardation was evident.

Inline with previous studies, cardiac, gastrointestinal and renal malformation are the most common associated abnormalities seen in single umbilical artery malformation and in the presence of multiple anomalies intrauterine growth retardation is expected

Professional ethics is an important component in providing good quality nursing care and for performance. Only those who are in the position to receive these services can measure professional ethics and quality of care indicators.

This descriptive-correlational study was performed with the participation of 287 nurses and 287 hospitalized patients in 5 teaching hospitals of Hamedan in 2021. Data were collected using demographic information questionnaires, nursing professional ethics and quality of care questionnaire. Data were analyzed by using descriptive and inferential statistics.

The results showed that the majority of nurses (78.8%) rated their performance with good professional ethics and the mean of the quality of care of the patients was 143.2±13.51. Also, the highest quality of nursing care from patients' point of view was in the psychosocial field and the lowest quality of nursing care was in the communicative domain, and there was no significant relationship between adherence to professional ethics and quality of nursing care delivery (p value = 0.988).

According to the findings of the study on the lack of relationship between professional ethics and quality of nursing care from the point of view of nurses and patients, therefore it seems necessary to take measures to develop educational programs regarding the importance of ethical compliance by nurses and awareness of thecomponents of quality care for patients.

The aim of this study was to compare the abnormal uterine bleeding with a history of cesarean section and normal delivery in women referred to the gynecology and obstetrics clinic of Ali Ibn Abitaleb Hospital in Zahedan, Iran in 2020-21.

Patients were divided into two groups of 100 patients. For each patient, information including demographic characteristics and evaluation of the causes of abnormal uterine bleeding in patients based on paraclinical procedures, BMI calculation, vaginitis and Pelvic inflammatory disorder (PID) were obtained.

The mean age of patients in the normal delivery group was 30.14 ± 6.26 years and in the cesarean section patients was 29.13 ± 6.70 years. There was no statistically significant difference between the two groups in terms of age. There was a statistically significant difference between the two groups in terms of type between menorrhagia (p value = 0.047) and in comparison between the two groups in terms of bleeding causes, anatomical cause (p value = 0.02) and neoplasia (p value = 0.04).

The present findings showed that the incidence of menorrhagia was higher in cesarean delivery and the incidence of abnormal uterine bleeding (AUB) in cesarean delivery may occur after delivery with a shorter time interval than the delivery time. The most important cause of abnormal bleeding in both groups was infection, but with regards to anatomical causes, the most important cause was fibroids in both groups.

Nitrate is an essential nutrient for the growth of plants. The presence of it in vegetables, water and other foods, is a serious threat for human health. Human body receives about 80% of nitrate from fruits and vegetables. The purpose was to determine the amount of nitrates in some vegetables and cucurbits (basil, mint, radish and tomato) that are sold in fruit and vegetable market of Zahedan city in 2020 year.

Hundred and twenty samples were selected and their nitrate content were measured by HPLCmethod. The significance level was less than 5%.

Mean of nitrate in, tomato, mint, radish and basil were 20.55, 515.76, 585.73 and 591.7mg/kg respectively. The mean of nitrate in basil was slightly higher than the radish but difference wasn’t statistically significant. There was statistically significantdifference among mean of nitrate in investigated vegetables (p value < 0.05). Mean of nitrate in basil was higher than others (p value < 0.05). A statistically significant difference was observed among mean of nitrate in vegetables namely tomato, mint, radish and basil in the investigated stalls (p value < 0.05).

Amount of nitrate in samples were lower than the national standard limit that is not harmful for human health. It can be concluded that the vegetables sold in Zahedan city are good interms of nitrate content and they don’t cause health problems. As high consumption rate of different type of vegetables by human and variation of their nitrate concentration, additional investigation and permanent control of their nitrate concentration isnecessary.

Occasionally the disease severity of CML, nay progressat an accelerated rate and the blast phase could be associated with a worse prognosis and a higher mortality rate. Exosomes are nanosized lipid vesicles with the ability to regulate various intra and extracellular mechanisms through transferring their content including proteins, RNAs, miRNAs and DNAs to the tumor microenvironment.

In this study, we aimed to review exosomes structure and biogenesis as well as different exosome sources like CML cells, mesenchymal stromal cells (MSCs), and immune cells. Moreover, the effects of secreted exosomes on CML disease such as their impact on bone marrow niche, drug resistance, leukemic cells growth and CML disease progression is briefly described here.

Since exosomes play extensive roles in the regulation of niche altered by cancer, they can be very valuable in the clinic and in investigating the causes of resistance to treatment. Therefore, one of the therapeutic strategies that can be useful in the recovery process of this group of relapsed patients are exosomes.

In order to prevent disease advancement to accelerated and blast phases, further investigations and clinical trials are required to identify the exact function of exosomes. Therefore, exploring the content of these exosomes and optimizing their application for disease treatment, is needed to prevent disease progression and drug resistance.