فهرست مطالب

Eurasian Chemical Communications
Volume:5 Issue: 6, Jun 2023

  • تاریخ انتشار: 1402/03/11
  • تعداد عناوین: 7
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  • Hala Shkyair Lihumis *, Abbas Sami Abd, Dalia Sadiq Mahdi Al-Khateeb, Hayfaa A. Mubarak, Mustafa M. Karhib, Mohanad Mousa Kareem, Saadon Abdullah Aowda Pages 466-482
    Research involved preparing new compounds from hydroxyquioline with formaldehyde to form P1 and then reacted with benzylalcohol to form P2 reacted chloroaceticacid  and SOCl2 to form P3 and P4   with thiosemicarbazide to form P5 and P2 reacted with benzydehyde to form chalcone reacted with H2O2 to form P8. The compounds were identified via TLC, FTIR 1HNMR and 13CNMR. The measured the antibacterial and antioxidant activity of the prepared compounds, to give high resulte.
    Keywords: hydroxyquioline, benzylalcohol, Formaldehyde, Thiosemicarbazide, benzydehyde antioxidant, Biological activity
  • Rabab L. Zughir *, Samah H. Kadhim, Dawod S. Abid Pages 483-491
    Selected cationic Gemini surfactants were effective in separating water-oil emulsions, whereas cationic Gemini surfactants are (R1 and R2) with alkyl chain lengths of 5 and 6. Their characterization was done by FTIR, 1H-NMR, and 13C-NMR characters of these "new Gemini surfactants". These Gemini surfactants' basic surface properties were investigated by measuring the relationship between electrical conductivity and surfactant concentration to determine critical micelles concentration CMC. Demulsification (emulsion breaking) is necessary in many practical applications as the petroleum industry and wastewater treatment in environmental technology. Demulsifiers with amine were used for breaking of water in crude oil emulsion in this study. The relative rate of water separation was determined via breaker tests. The demulsifier which has longer alkyl chain length had a better performance on breaking emulsion than demulsifier which has shorter alkyl chain length.
    Keywords: Cationic Gemini surfactants, Electrical conductivity, critical micelle concentration, Demulsifier, interfacial film, water in oil emulsion
  • Akram Muhamed Musa *, Wathiq Abdul-Hassan Pages 492-521
    Preparation of AAN and ACl is performed by reaction 1 equivalent of en and 2 equivalents of acetyl acetone and 3-chloro acetyl acetone, respectively. Fe2+, Co2+, and Ni2+complexes with both bis(acetylacetone) ethylenediimine AAN and bis(3-chloroacetylacetone) ethylenediimine ACl ware synthesized. The adduct complex [Fe(AAN)(bpy)2] was also synthesized from reaction of [Fe(AAN)(H2O)2] with 4,4’-bipyridine. These N2O2 metal complexes have been characterized by FT-IR, UV-Vis, and TG analysis as well as XRD spectrometries. Interaction of 4,4’-bipyridine (bpy) with metal (II) complexes in solution affords adduct complexes, i.e. through coordination of bpy with metal ion (II). Interaction of  with metal (II) complexes in solution affords adduct complexes, i.e. through coordination of  with metal ion (II). The solutions of adduct complexes happened among bis-viologen  and metal complexes have been reduced by activated zinc powder to afford viologen-based molecular switches.
    Keywords: Bis(acetylacetone) ethylenediimine, Bis(3-chloroacetylacetone) ethylenediimine, Adduct, 4, 4’– bipyridine, Viologen switches, metal (II) complexes
  • Seema Kasim, Fadia Al-Bazzaz, Sawsan Hammoodi, Yasser Mustafa * Pages 522-535

    Schiff base-inorganic complexes have significantly contributed to the development of modern drug design due to their significance in a number of multi-discipline study fields. This nearly exhaustive review examines every aspect and characteristic of these complexes, with a focus on a few key biomedical traits. Schiff base, the organic component of these complexes, is formed by the condensation of two important molecules: a carbonyl and a primary amine framework. Organic compounds based on the Schiff base moiety have been demonstrated to have biomedical attributes such as antibacterial, antioxidant, antifungal, antineoplastic, and antiviral properties. In the light of these attributes and the recent advances in the domain of coordinating chemistry, many research outcomes suggest the Schiff base-inorganic complexes as a potential core for medicinally active coordinated compounds and for reaction catalysis. This suggestion is supported by numerous new research findings that document the properties of these complexes as antimicrobial, antioxidant candidates, and efficient promoters in various chemical reactions.

    Keywords: Schiff base, Inorganic complexes, Reaction catalysis, Antimicrobial, Antioxidant
  • Qais Lahhob *, Ali Al-Sanaf, Nidhal Mohammed, Hamed Abbas, Zahraa Ibrahim, Murtadha Najim, Zahraa Malik, Zainab Budaiwi, Zainab Abdul-Jabbar, Mustafa Kadham Pages 536-555

    Minerals are inorganic substances present in the tissues and fluids of our bodies. They are divided into macro minerals (Ca, Mg, K, Na, Cl, P, and S) and microminerals (I, Zn, Si, Fe, Mn, Cu, Co, Mo, F, Cr, and B), which are important for health and should be consumed according to the needs of the organism. Essential minerals have well-characterized physiological functions within the body. The ability of the body to maintain the minerals content within a certain range despite varying intakes, involves the processes of absorption, storage, and excretion. Inappropriate intakes and/or elevated requirements result from a range of conditions, including disease, malabsorption, pregnancy, and excessive losses, lead to deficiency. A severe deficiency of an essential mineral can only be corrected by supplementation. This review provides some detailed information about dietary sources, biological effects, deficiency, and toxicity of minerals and trace elements.

    Keywords: Substances, trace elements, Absorption, Excretion, Toxicity
  • Nahid Asghari, Sepideh Houshmand, Amir Rigi, Vahid Mohammadzadeh, Mehrdad Piri Dizaj, Zahra Sadat Mousavian Hiagh * Pages 556-568
    This study aimed to PEGylated cationic nano-niosomes formulation containing curcumin (CUR) for drug delivery to MCF-7 breast cancer cell lines and slow release of encapsulated CUR to reduce drug side effects on other healthy cells and increase drug effect on cancer cells. In this applied/in vitro study, PEGylated cationic nano-niosomes containing curcumin as herbal anticancer drug  in MCF-7 cell line were prepared in laboratory through lipid phase mixing, phosphate buffer addition to a lipid thin film, and the production of nano-niosomes by sonication and dialysis process. Curcumin-containing niosomes were produced using the lipid phase by thin film fabrication method and reduced to a nanometer size by sonication. The average diameter (85.4 nm) of drug-carrying nano-niosomes was determined using a nano-sizer. Our results includes acquisition of technical knowledge of fabricating nano-niosomes containing a herbal bioactive ingredient as a nanosystem with the herbal medicine curcumin, proper loading of curcumin (with anticancer effect) at > 95% inside nano-niosomes with a size of < 100 nm to intensify the effectiveness of this medicine in cancer treatment, and preparation of PEGylated cationic nano-niosomes containing a body-compatible herbal bioactive substance with a slow release curve and good stability in terms of size and surface loading after 2 months of production. The produced curcumin-carrying liposomal nano-carrier has a slow-release curve and body biocompatibility that can be used in preparation of drug delivery systems containing similar hydrophobic drugs as an effective approach in treatment of various cancers, and agriculture, as well as in various pharmaceutical, medical, health, and environmental industries.
    Keywords: curcumin, Breast cancer cell, Bioactive, Nano-niosomes, PEGylated, MCF-7 Cancer Cell, Drug Delivery
  • Farid Hamedi, Amanollah Zarei Ahmady *, Abdolghani Ameri, Heibatolah Kalantari, Zahra Nazari Khorasgani Pages 569-575
    In the present work, Se and Mn analysis was carried out among some popular Iranian herbal drops to monitor a possible accumulation of adverse elements. In this study, five different herbal drops present in Iranian market were selected, and 45 samples of each (totally 225 samples) were collected, and analyzed for the presence and determination of selenium and manganese using graphite furnace atomic absorption spectrometry. Samples were prepared by the dry ashing method at 450 °C, and the residue was dissolved in nitric acid. Se and Mn contents were determined using calibration curves at wavelength 196.0 and 279.5 nm respectively. LOD of the methods were determined as 9.1 µgL-1 for Se and 0.9 µgL-1 for Mn. LOQs were calculated to be 30.0 and 3.0 µgL-1 for Se and Mn, respectively. The Se concentrations in the determined samples were between ND-21.0 µgL-1 and for Mn were in the range of 7.2-1840.7 µgL-1. Mean Se and Mn concentrations (µgL-1) were 4.7 and 43.7 for Vitagnus, 9.6 and 185.1 for Hypiran, 13.3 and 338.5 for Carminat, 21.0 and 1840.7 for Persica, and ND and 7.2 for Menthol, respectively. The results showed that Mn was present in all of the samples analyzed, but no selenium was detected in some herbal drop samples.
    Keywords: Herbal drops, selenium, manganese, Graphite furnace atomic absorption, Spectroscopy